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View article: Overweight prevalence increases from 2 to 8 years of age among children with immigrant background in a Norwegian multiethnic population
Overweight prevalence increases from 2 to 8 years of age among children with immigrant background in a Norwegian multiethnic population Open
Aims: Little is known about ethnic disparities in childhood obesity in Europe. We explored the development of ethnic differences in overweight (including obesity) from age 2 to 8 years. Methods: We collected routine weight and height measu…
View article: Diabetes and prediabetes among women universally screened for gestational diabetes: a multi-ethnic, population-based, prospective study with eleven years follow-up
Diabetes and prediabetes among women universally screened for gestational diabetes: a multi-ethnic, population-based, prospective study with eleven years follow-up Open
View article: Development and validation of a prognostic model to predict birth weight: individual participant data meta-analysis
Development and validation of a prognostic model to predict birth weight: individual participant data meta-analysis Open
Objective To predict birth weight at various potential gestational ages of delivery based on data routinely available at the first antenatal visit. Design Individual participant data meta-analysis. Data sources Individual participant data …
View article: Development and validation of prediction models for fetal growth restriction and birthweight: an individual participant data meta-analysis
Development and validation of prediction models for fetal growth restriction and birthweight: an individual participant data meta-analysis Open
Background Fetal growth restriction is associated with perinatal morbidity and mortality. Early identification of women having at-risk fetuses can reduce perinatal adverse outcomes. Objectives To assess the predictive performance of existi…
View article: Exploring Structural Uncertainty in Cost-Effectiveness Modeling of Gestational Diabetes Screening: An Application Example from Norway
Exploring Structural Uncertainty in Cost-Effectiveness Modeling of Gestational Diabetes Screening: An Application Example from Norway Open
Background Screening pregnant women for gestational diabetes mellitus (GDM) has recently been expanded in Norway, although screening eligibility criteria continue to be debated. We aimed to compare the cost-effectiveness of alternative GDM…
View article: Placental weight, surface area, shape and thickness - Relations with maternal ethnicity and cardio-metabolic factors during pregnancy
Placental weight, surface area, shape and thickness - Relations with maternal ethnicity and cardio-metabolic factors during pregnancy Open
View article: DNA methylation risk score for type 2 diabetes is associated with gestational diabetes
DNA methylation risk score for type 2 diabetes is associated with gestational diabetes Open
View article: Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain
Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain Open
Objectives We aimed to discover CpG sites with differential DNA methylation in peripheral blood leukocytes associated with body mass index (BMI) in pregnancy and gestational weight gain (GWG) in women of European and South Asian ancestry. …
View article: DNA methylation risk score for type 2 diabetes is associated with gestational diabetes
DNA methylation risk score for type 2 diabetes is associated with gestational diabetes Open
Background Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) share many pathophysiological factors including genetics, but whether epigenetic marks are shared is unknown. We aimed to test whether a DNA methylation ris…
View article: Employing fasting plasma glucose to safely limit the use of oral glucose tolerance tests in pregnancy: a pooled analysis of four Norwegian studies
Employing fasting plasma glucose to safely limit the use of oral glucose tolerance tests in pregnancy: a pooled analysis of four Norwegian studies Open
Background/objective There is no international consensus about the optimal approach to screening and diagnosis of gestational diabetes mellitus (GDM). Fasting plasma glucose (FPG) has been proposed as an alternative universal screening tes…
View article: Cohort profile update: the Norwegian STORK Groruddalen (STORK G) pregnancy and birth cohort—the role of ethnicity and causal pathways for obesity, type 2 diabetes, cardiovascular disease and other health issues
Cohort profile update: the Norwegian STORK Groruddalen (STORK G) pregnancy and birth cohort—the role of ethnicity and causal pathways for obesity, type 2 diabetes, cardiovascular disease and other health issues Open
Purpose The STORK Groruddalen cohort was set up in 2008 to explore ethnic differences in: (1) maternal health , primarily gestational diabetes (GDM) and related health issues during pregnancy and post partum, and effects of exposures on ri…
View article: Adverse pregnancy outcomes among women in Norway with gestational diabetes using three diagnostic criteria
Adverse pregnancy outcomes among women in Norway with gestational diabetes using three diagnostic criteria Open
Introduction The aim of this study was to examine the risk of adverse perinatal outcomes in women diagnosed with GDM by the World Health Organization (WHO) 1999 criteria, and in those retrospectively identified by the Norwegian-2017 and WH…
View article: The impact of recommending iron supplements to women with depleted iron stores in early pregnancy on use of supplements, and factors associated with changes in iron status from early pregnancy to postpartum in a multi-ethnic population-based cohort
The impact of recommending iron supplements to women with depleted iron stores in early pregnancy on use of supplements, and factors associated with changes in iron status from early pregnancy to postpartum in a multi-ethnic population-based cohort Open
View article: Seasonal variation in gestational diabetes mellitus among women in Norway: a national population-based study
Seasonal variation in gestational diabetes mellitus among women in Norway: a national population-based study Open
Objectives Previous research on seasonal variation in the incidence of gestational diabetes mellitus (GDM) has shown inconclusive results. Furthermore, little is known about whether a seasonal variation in GDM might be associated with the …
View article: Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain
Epigenome-wide association study of DNA methylation in maternal blood leukocytes with BMI in pregnancy and gestational weight gain Open
Objectives We aimed to discover CpG sites with differential methylation in peripheral blood leukocytes associated with body mass index (BMI) in pregnancy and gestational weight gain (GWG) in women of European and South Asian ancestry. Furt…
View article: Autonomic cardiovascular control after heart transplantation
Autonomic cardiovascular control after heart transplantation Open
Heart transplantation is lifesaving and a rescue treatment for patients with end-stage heart failure. Normally, heart function is intimately controlled by the autonomic nervous system. However, due to the transplant procedure, the donor he…
View article: Epigenome-Wide Association Study of Serum Folate in Maternal Peripheral Blood Leukocytes
Epigenome-Wide Association Study of Serum Folate in Maternal Peripheral Blood Leukocytes Open
Aim: To perform an epigenome-wide association study (EWAS) of serum folate in maternal blood. Methods: Cross-ancestry (Europeans = 302, South Asians = 161) and ancestry-specific EWAS in the EPIPREG cohort were performed, foll…
View article: Cross-Ancestry DNA Methylation Marks of Insulin Resistance in Pregnancy: An Integrative Epigenome-Wide Association Study
Cross-Ancestry DNA Methylation Marks of Insulin Resistance in Pregnancy: An Integrative Epigenome-Wide Association Study Open
Although there are some epigenome-wide association studies (EWAS) of insulin resistance, for most of them authors did not replicate their findings, and most are focused on populations of European ancestry, limiting the generalizability. In…
View article: Insulin and Body Mass Index Decrease Serum Soluble Leptin Receptor Levels in Humans
Insulin and Body Mass Index Decrease Serum Soluble Leptin Receptor Levels in Humans Open
Context Serum soluble leptin receptor (sOb-R) may protect against future type 2 diabetes or serve as a marker for protective features, but how sOb-R is regulated is largely unknown. Objective This work aimed to test how serum sOb-R is infl…
View article: Effects of race and ethnicity on perinatal outcomes in high-income and upper-middle-income countries: an individual participant data meta-analysis of 2 198 655 pregnancies
Effects of race and ethnicity on perinatal outcomes in high-income and upper-middle-income countries: an individual participant data meta-analysis of 2 198 655 pregnancies Open
View article: Epigenome-wide association study of serum folate in maternal peripheral blood leukocytes
Epigenome-wide association study of serum folate in maternal peripheral blood leukocytes Open
Aim To perform an epigenome-wide association study (EWAS) of serum folate in maternal blood. Methods We performed cross-ancestry (Europeans=302, South Asians=161) and ancestry-specific EWAS in the EPIPREG cohort, followed by methyl quantit…
View article: Lipid and lipoprotein concentrations during pregnancy and associations with ethnicity
Lipid and lipoprotein concentrations during pregnancy and associations with ethnicity Open
View article: Prevalence of postpartum anaemia and iron deficiency by serum ferritin, soluble transferrin receptor and total body iron, and associations with ethnicity and clinical factors: a Norwegian population-based cohort study
Prevalence of postpartum anaemia and iron deficiency by serum ferritin, soluble transferrin receptor and total body iron, and associations with ethnicity and clinical factors: a Norwegian population-based cohort study Open
Worldwide, there are limited data on the prevalence of postpartum anaemia and iron status. The aims of the present study were to assess the prevalence of anaemia and iron deficiency (ID) by three iron indicators 14 weeks postpartum, their …
View article: Additional file 3 of Lipid and lipoprotein concentrations during pregnancy and associations with ethnicity
Additional file 3 of Lipid and lipoprotein concentrations during pregnancy and associations with ethnicity Open
Additional file 3: Table S1a. Concentrations of lipids and lipoproteins (mmol/L) at gestational age (GA) 15 by ethnic groups. Values in mean and 95% CI. Table S1b. Concentrations of lipids and lipoproteins (mmol/L) at gestational age (GA) …
View article: Maternal Glucose and LDL-Cholesterol Levels Are Related to Placental Leptin Gene Methylation, and, Together With Nutritional Factors, Largely Explain a Higher Methylation Level Among Ethnic South Asians
Maternal Glucose and LDL-Cholesterol Levels Are Related to Placental Leptin Gene Methylation, and, Together With Nutritional Factors, Largely Explain a Higher Methylation Level Among Ethnic South Asians Open
Background Leptin, mainly secreted by fat cells, plays a core role in the regulation of appetite and body weight, and has been proposed as a mediator of metabolic programming. During pregnancy leptin is also secreted by the placenta, as we…
View article: Identifying women with gestational diabetes based on maternal characteristics: an analysis of four Norwegian prospective studies
Identifying women with gestational diabetes based on maternal characteristics: an analysis of four Norwegian prospective studies Open
View article: Cohort profile: Epigenetics in Pregnancy (EPIPREG) – population-based sample of European and South Asian pregnant women with epigenome-wide DNA methylation (850k) in peripheral blood leukocytes
Cohort profile: Epigenetics in Pregnancy (EPIPREG) – population-based sample of European and South Asian pregnant women with epigenome-wide DNA methylation (850k) in peripheral blood leukocytes Open
Pregnancy is a valuable model to study the association between DNA methylation and several cardiometabolic traits, due to its direct potential to influence mother’s and child’s health. Epigenetics in Pregnancy (EPIPREG) is a population-bas…
View article: Thyroid Function During Pregnancy in A Multiethnic Population in Norway
Thyroid Function During Pregnancy in A Multiethnic Population in Norway Open
Context Ethnic differences in thyroid function during pregnancy have been reported. However, it is unclear if this is equally valid across ethnic groups within multiethnic populations. Objective We aimed to assess ethnic differences in thy…
View article: Childhood vascular phenotypes have differing associations with prenatal and postnatal growth
Childhood vascular phenotypes have differing associations with prenatal and postnatal growth Open
Objective: In children aged 8--9 years, we examined the associations of linear and abdominal circumference growth during critical stages of prenatal and postnatal development with six vascular measurements commonly used as early markers of…
View article: Identifying women with gestational diabetes based on maternal characteristics: An analysis of four Norwegian prospective studies
Identifying women with gestational diabetes based on maternal characteristics: An analysis of four Norwegian prospective studies Open
Background There is still no worldwide agreement on the best diagnostic thresholds to define gestational diabetes (GDM) or the optimal approach for identifying women with GDM. Should all pregnant women perform an oral glucose tolerance tes…