Yi Zhu
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View article: Nylon Powder Composites with High Leveling Property and Toughness Prepared via Filler-Modified Method
Nylon Powder Composites with High Leveling Property and Toughness Prepared via Filler-Modified Method Open
Powder coating, as a promising coating material, has attracted widespread attention due to its convenient construction and being a green option, promoting environmental protection. However, the existence of defects such as insufficient lev…
View article: Enhancing Boundary Precision and Long-Range Dependency Modeling in Medical Imaging via Unified Attention Framework
Enhancing Boundary Precision and Long-Range Dependency Modeling in Medical Imaging via Unified Attention Framework Open
This study addresses the common challenges in medical image segmentation and recognition, including boundary ambiguity, scale variation, and the difficulty of modeling long-range dependencies, by proposing a unified framework based on a hi…
View article: Global burden of ischemic heart disease attributable to dietary factors: insights from the global burden of disease study 2021
Global burden of ischemic heart disease attributable to dietary factors: insights from the global burden of disease study 2021 Open
Background Dietary risk factors remain a leading modifiable contributor to ischemic heart disease (IHD), yet global trends and inequities in diet-attributable IHD burden remain incompletely quantified. This study examines the global, regio…
View article: The impact of perineural invasion on prognosis in esophageal cancer patients after surgery: a systematic review and meta-analysis
The impact of perineural invasion on prognosis in esophageal cancer patients after surgery: a systematic review and meta-analysis Open
Objective This study aims to update the prognostic value of perineural invasion(PNI) in various subgroups of esophageal cancer patients. Methods We searched databases including PubMed, Scopus, Wiley, Web of Science, and Embase for full-tex…
View article: Continuous Preparation of Carbon Nanotubes/Carbon Fiber Reinforcement Using Fe-Ni Bimetallic Catalyst
Continuous Preparation of Carbon Nanotubes/Carbon Fiber Reinforcement Using Fe-Ni Bimetallic Catalyst Open
Surface modification of carbon fibers (CFs) is a critical step in preparing carbon fiber-reinforced composites. This study developed a continuous experimental process that integrates electrochemical anodic oxidation and chemical vapor depo…
View article: Enabling Self-Improving Agents to Learn at Test Time With Human-In-The-Loop Guidance
Enabling Self-Improving Agents to Learn at Test Time With Human-In-The-Loop Guidance Open
Large language model (LLM) agents often struggle in environments where rules and required domain knowledge frequently change, such as regulatory compliance and user risk screening. Current approaches, like offline fine-tuning and standard …
View article: A Transformer-Based Pavement Crack Segmentation Model with Local Perception and Auxiliary Convolution Layers
A Transformer-Based Pavement Crack Segmentation Model with Local Perception and Auxiliary Convolution Layers Open
Crack detection in complex pavement scenarios remains challenging due to the sparse small-target features and computational inefficiency of existing methods. To address these limitations, this study proposes an enhanced architecture based …
View article: A bispecific antibody–drug conjugate targeting EGFR and HER3 in metastatic esophageal squamous cell carcinoma: a phase 1b trial
A bispecific antibody–drug conjugate targeting EGFR and HER3 in metastatic esophageal squamous cell carcinoma: a phase 1b trial Open
Research on patients with advanced esophageal squamous cell carcinoma (ESCC) who have progressed on immunotherapy remains limited. BL-B01D1 is a first-in-class antibody-drug conjugate consisting of an EGFR-HER3 bispecific antibody bound to…
View article: PI-RADSv2.1 combined with PSA density for optimizing prostate biopsy decisions: a retrospective analysis
PI-RADSv2.1 combined with PSA density for optimizing prostate biopsy decisions: a retrospective analysis Open
Objective This study aimed to explore the application value of the Prostate Imaging Reporting and Data System version 2.1 (PI-RADS v2.1) combined with prostate-specific antigen density (PSAD) for guiding prostate biopsy, with the goal of i…
View article: Changes in the ocular surface and meibomian glands following administration of 0.01 and 0.02% atropine
Changes in the ocular surface and meibomian glands following administration of 0.01 and 0.02% atropine Open
Purpose To investigate the changes in the ocular surface and meibomian glands following the administration of 0.01 and 0.02% atropine. Setting The Second Affiliated Hospital of Anhui Medical University, Anhui, China. Methods In this random…
View article: Sudden Death With Lyme Disease Myocarditis
Sudden Death With Lyme Disease Myocarditis Open
Death from myocarditis due to Lyme disease is uncommon but may be under-recognized. Myocarditis can lead to sudden and/or unexpected death due to fatal cardiac arrhythmias, which may be misattributed to more common causes, such as coronary…
View article: Nuclear NAD+ synthase nicotinamide mononucleotide adenylyltransferase 1 contributes to nuclear atypia and promotes glioma growth
Nuclear NAD+ synthase nicotinamide mononucleotide adenylyltransferase 1 contributes to nuclear atypia and promotes glioma growth Open
Background Glioma is a malignant primary brain tumor with a poor prognosis and short survival. NAD+ is critical for cancer growth; however, clinical trials targeting NAD+ biosynthesis had limited success, indicating the need for mechanisti…
View article: Genetic Susceptibility to Psoriasis Increases Risk of Depression: Evidence From a Mendelian Randomization Study
Genetic Susceptibility to Psoriasis Increases Risk of Depression: Evidence From a Mendelian Randomization Study Open
Objective Observational studies indicate that psoriasis (PSO) patients have an increased risk of depression; however, potential confounding factors and reverse causality limit these findings, leaving the exact causal relationship between t…
View article: A physics-guided symbolic regression framework for efficient and interpretable sand constitutive modeling
A physics-guided symbolic regression framework for efficient and interpretable sand constitutive modeling Open
Data-driven constitutive modeling for geomaterials encounters significant challenges in achieving a balance among interpretability, physical consistency, and computational efficiency. Traditional symbolic regression often struggles with ex…
View article: Discordant Information on Blinding in Trial Registries and Published Research
Discordant Information on Blinding in Trial Registries and Published Research Open
Importance Blinding of individuals involved in randomized clinical trials (RCTs) can be used to protect against performance and biases, but discrepancies in the reporting of methodological features between registered protocols and subseque…
View article: Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, <scp>IDH</scp>‐wildtype
Molecular profile of adult primary leptomeningeal gliomatosis aligns with glioblastoma, <span>IDH</span>‐wildtype Open
Adult primary leptomeningeal gliomatosis (PLG) is a rare, rapidly progressive and fatal disease characterized by prominent leptomeningeal infiltration by a glial tumor without an identifiable parenchymal mass. The molecular profile of adul…
View article: Age-related cerebral changes during different n-back tasks: a functional near-infrared spectroscopy study
Age-related cerebral changes during different n-back tasks: a functional near-infrared spectroscopy study Open
Background The n-back task is a widely used paradigm to assess working memory and is commonly applied in research on age-related cognitive decline. However, studies utilizing functional near-infrared spectroscopy (fNIRS) to explore this ar…
View article: Regulation of proteostasis by sleep through autophagy in <i>Drosophila</i> models of Alzheimer’s disease
Regulation of proteostasis by sleep through autophagy in <i>Drosophila</i> models of Alzheimer’s disease Open
Sleep and circadian rhythm dysfunctions are common clinical features of Alzheimer’s disease (AD). Increasing evidence suggests that in addition to being a symptom, sleep disturbances can also drive the progression of neurodegeneration. Pro…
View article: Prostaglandin I2 signaling prevents angiotensin II-induced atrial remodeling and vulnerability to atrial fibrillation in mice
Prostaglandin I2 signaling prevents angiotensin II-induced atrial remodeling and vulnerability to atrial fibrillation in mice Open
Atrial fibrillation (AF) is the most common arrhythmia, and atrial fibrosis is a pathological hallmark of structural remodeling in AF. Prostaglandin I2 (PGI2) can prevent the process of fibrosis in various tissues via cell surface Prostagl…
View article: NFHP-RN: A Method of Few-Shot Network Attack Detection Based on the Network Flow Holographic Picture-ResNet
NFHP-RN: A Method of Few-Shot Network Attack Detection Based on the Network Flow Holographic Picture-ResNet Open
Due to the rapid evolution of Advanced Persistent Threats (APTs) attacks, the emergence of new and rare attack samples, and even those never seen before, make it challenging for traditional rule-based detection methods to extract universal…
View article: LensAge index as a deep learning-based biological age for self-monitoring the risks of age-related diseases and mortality
LensAge index as a deep learning-based biological age for self-monitoring the risks of age-related diseases and mortality Open
Age is closely related to human health and disease risks. However, chronologically defined age often disagrees with biological age, primarily due to genetic and environmental variables. Identifying effective indicators for biological age i…