Lingling Wang
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View article: Stage-specific gut microbial restructuring drives estrous transition in rabbits
Stage-specific gut microbial restructuring drives estrous transition in rabbits Open
These findings demonstrate that gut microbiota restructuring regulates the estrous transition of rabbits, providing a basis for developing microbiota-targeted strategies to enhance reproductive efficiency in rabbit production and optimize …
View article: Baicalin inhibits infectious bronchitis virus replication via MAVS-dependent interferon-β upregulation and mitochondrial function preservation
Baicalin inhibits infectious bronchitis virus replication via MAVS-dependent interferon-β upregulation and mitochondrial function preservation Open
The inhibitory effect of baicalin on infectious bronchitis virus (IBV) replication is closely related to expression of the mitochondrial antiviral signaling protein (MAVS) in chicken embryonic kidney (CEK) cells. Baicalin significantly upr…
View article: Effect of Boundary-layer Suction on the Performance of an Intake under Off-design Condition
Effect of Boundary-layer Suction on the Performance of an Intake under Off-design Condition Open
Under off-design conditions, shock wave-boundary layer interaction (SWBLI) and large-scale separation within the intake become prominent, leading to significant decrease in aerodynamic performance. By introducing a boundary layer suction s…
View article: Research on the conversion pattern of 6-gingerol in stir-fried ginger and the protective activity mechanism of its conversion products on HUVECs
Research on the conversion pattern of 6-gingerol in stir-fried ginger and the protective activity mechanism of its conversion products on HUVECs Open
Gingerol compounds are the main active and spicy components in ginger, among which 6-gingerol has the highest content. Gingerol compounds have an unstable structure due to multiple phenolic hydroxyl groups. During drying, heating, and proc…
View article: Preoperative systemic inflammation response index may predict postoperative delayed extubation for elderly patients with aSAH: a retrospective cohort study
Preoperative systemic inflammation response index may predict postoperative delayed extubation for elderly patients with aSAH: a retrospective cohort study Open
Background Aneurysmal subarachnoid hemorrhage (aSAH) is one common neurosurgical emergency and severe disease, with high morbidity and mortality. Delayed extubation (DE) is a confirmed risk factor for prolonged intensive care unit (ICU) st…
View article: Pilot Design for Block Compressed Sensing-Based MIMO-OFDM Channel Estimation with Joint Criterion
Pilot Design for Block Compressed Sensing-Based MIMO-OFDM Channel Estimation with Joint Criterion Open
This paper studies the pilot design for compressed sensing (CS)-based sparse channel estimation in multi-input–multi-output orthogonal frequency division multiplexing (MIMO-OFDM) systems. To improve the performance of estimating multiple j…
View article: Dual-Mode Aptamer AP1-F Achieves Molecular–Morphological Precision in Cancer Diagnostics via Membrane NCL Targeting
Dual-Mode Aptamer AP1-F Achieves Molecular–Morphological Precision in Cancer Diagnostics via Membrane NCL Targeting Open
Nucleic acid aptamers leverage defined tertiary structures for precise molecular recognition, positioning them as transformative biomedical tools. We engineered AP1-F, a G-quadruplex (G4)-structured aptamer that selectively binds membrane-…
View article: Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials
Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials Open
Immune checkpoint inhibitors (ICIs) are widely used to treat advanced non‐small cell lung cancer (NSCLC). However, it remains crucial to identify patients who are unlikely to benefit from immunotherapy and to explore potential combination …
View article: Bridging the gap: Computer-aided detection and Yamada classification system matches expert performance
Bridging the gap: Computer-aided detection and Yamada classification system matches expert performance Open
BACKGROUND Computer-aided diagnosis (CAD) may assist endoscopists in identifying and classifying polyps during colonoscopy for detecting colorectal cancer. AIM To build a system using CAD to detect and classify polyps based on the Yamada c…
View article: Upper-limb symptom clusters and their associations with surgical complications among breast cancer survivors: A cross-sectional study
Upper-limb symptom clusters and their associations with surgical complications among breast cancer survivors: A cross-sectional study Open
View article: Integrating Peridynamic Theory with Ground Fissure Mechanics: Application to Songzhuang Ground Fissure Study
Integrating Peridynamic Theory with Ground Fissure Mechanics: Application to Songzhuang Ground Fissure Study Open
This study explores the application of Peridynamic (PD) theory in ground fissure modeling and simulation, focusing on the Songzhuang region in Beijing. Traditional methods often encounter difficulties in accurately capturing fissure format…
View article: Toward Precision Nutrition Standards: Molecular Profiling of GSE OPCs and Gaps in Current Regulations
Toward Precision Nutrition Standards: Molecular Profiling of GSE OPCs and Gaps in Current Regulations Open
Grape seed extract (GSE) is widely utilized in functional foods and dietary supplements due to its antioxidant and anti-aging potential, with much of its bioactivity attributed to oligomeric proanthocyanidins (OPCs). However, current quali…
View article: AI‐Assisted Detection of Early Gastric Cancer via Visualization of Mucosal Acidity Compromise During Endoscopy
AI‐Assisted Detection of Early Gastric Cancer via Visualization of Mucosal Acidity Compromise During Endoscopy Open
Accurate localization of early gastric cancer (EGC) remains challenging due to its morphological resemblance to gastritis. This study presents an artificial intelligence (AI)‐assisted bedside diagnostic system to enhance EGC detection by v…
View article: Toward Precision Nutrition Standards: Molecular Profiling of GSE OPCs and Gaps in Current Regulations
Toward Precision Nutrition Standards: Molecular Profiling of GSE OPCs and Gaps in Current Regulations Open
Grape seed extract (GSE) is widely utilized in functional foods and dietary supplements due to its antioxidant and anti-aging potential, with much of its bioactivity attributed to oligomeric proanthocyanidins (OPCs). However, current quali…
View article: The integrated analysis of SIRT family expression, prognostic value, and potential implications in childhood acute lymphoblastic leukemia
The integrated analysis of SIRT family expression, prognostic value, and potential implications in childhood acute lymphoblastic leukemia Open
Background Acute lymphoblastic leukemia (ALL) is a rapidly progressive hematological malignancy caused by the dysregulated proliferation and abnormal differentiation or differentiation block of lymphoid precursors. The sirtuin family, as a…
View article: The Impact of Artificial Intelligence on Corporate Revenue Growth: Evidence from China
The Impact of Artificial Intelligence on Corporate Revenue Growth: Evidence from China Open
Technological innovation in the AI sector is rapidly advancing, with achievements like AI patents emerging as key assets in corporate competition. While the direct revenue from individual patents may be limited in the short term, leveragin…
View article: Optimizing nursing care for neutropenic patients: a holistic perspective on education, support, and clinical management
Optimizing nursing care for neutropenic patients: a holistic perspective on education, support, and clinical management Open
Neutropenia, characterized by neutrophil counts below 1,500 cells/μL, increases infection risk and worsens treatment outcomes in oncology and immunocompromised patients. This paper outlines evidence-based nursing strategies in four domains…
View article: Volatile distribution inversion and rotation analysis of comet 103P/Hartley 2 using nongravitational effects
Volatile distribution inversion and rotation analysis of comet 103P/Hartley 2 using nongravitational effects Open
Aims . The rotational states of comet 103P/Hartley 2 (103P) during its perihelion passage are strongly modulated by nongravitational forces. By fitting its attitude-variation measurements, this study aims to infer the spatial distributions…
View article: Self-Assemblied Fe-Zol Nanoparticles In Neutrophils Promote Osteonecrosis Progression
Self-Assemblied Fe-Zol Nanoparticles In Neutrophils Promote Osteonecrosis Progression Open
Aim or purpose: To explore the mechanisms of bisphosphonate-related osteonecrosis of jaw (BRONJ) based on plasticity and iron metabolism in jawbone neutrophils. Materials and methods: Jawbone and femur injury model with/without Zoldronate …
View article: Editorial: Progress in clinical and mechanistic studies of severe respiratory viral infections in children
Editorial: Progress in clinical and mechanistic studies of severe respiratory viral infections in children Open
View article: Embryonic and Larval Development of an Interspecific Grouper Backcross Between the Kelp Grouper (Epinephelus moara) ♀ and KGGG (E. moara ♀ × E. lanceolatus ♂) ♂
Embryonic and Larval Development of an Interspecific Grouper Backcross Between the Kelp Grouper (Epinephelus moara) ♀ and KGGG (E. moara ♀ × E. lanceolatus ♂) ♂ Open
Backcrossing serves as an effective tool for interspecific gene introgression, facilitating germplasm improvement. To develop superior grouper aquaculture varieties, in this study, a backcrossed breed was constructed by crossing a male hyb…
View article: Association between history of pregnancy loss and preterm birth: the mediating role of maternal anxiety
Association between history of pregnancy loss and preterm birth: the mediating role of maternal anxiety Open
View article: Chemosensation of the pheromone spermine by the olfactory TAAR-like receptor TAAR348
Chemosensation of the pheromone spermine by the olfactory TAAR-like receptor TAAR348 Open
View article: Sustainable Conservation of Embroidery Cultural Heritage: An Approach to Embroidery Fabric Restoration Based on Improved U-Net and Multiscale Discriminators
Sustainable Conservation of Embroidery Cultural Heritage: An Approach to Embroidery Fabric Restoration Based on Improved U-Net and Multiscale Discriminators Open
As a vital carrier of China’s intangible cultural heritage, restoring damaged embroidery fabrics is essential for the sustainable preservation of cultural relics. However, existing methods face persistent challenges, such as mask pattern m…
View article: Probing the mass composition of TeV cosmic rays with HAWC
Probing the mass composition of TeV cosmic rays with HAWC Open
View article: AEAS: Actionable Exploit Assessment System
AEAS: Actionable Exploit Assessment System Open
Security practitioners face growing challenges in exploit assessment, as public vulnerability repositories are increasingly populated with inconsistent and low-quality exploit artifacts. Existing scoring systems, such as CVSS and EPSS, off…
View article: Reply on RC2
Reply on RC2 Open
View article: Reply on RC3
Reply on RC3 Open
View article: The Prevalence and Risk Factors of Hyperuricemia in Chinese Children and Adolescents: A Meta-Analysis
The Prevalence and Risk Factors of Hyperuricemia in Chinese Children and Adolescents: A Meta-Analysis Open
Objective: To explore the prevalence and risk factors of hyperuricemia in Chinese children and adolescents by meta-analysis.Material and Methods: The China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service platform, …
View article: Probing laser-driven surface and subsurface dynamics via grazing-incidence XFEL scattering and diffraction
Probing laser-driven surface and subsurface dynamics via grazing-incidence XFEL scattering and diffraction Open
We demonstrate a grazing-incidence x-ray platform that simultaneously records time-resolved grazing-incidence small-angle x-ray scattering (GISAXS) and grazing-incidence x-ray diffraction (GID) from a femtosecond laser-irradiated gold film…