Liang He
YOU?
Author Swipe
View article: Regulation of autonomic nervous system by acupuncture: a heart rate variability study on physical stress
Regulation of autonomic nervous system by acupuncture: a heart rate variability study on physical stress Open
Introduction This study aimed to investigate the effects of acupuncture and moxibustion, as well as various acupoints, on human autonomic nervous system (ANS) function and physical stress. The research further to identify effective interve…
View article: Exercise increases bone mass by lactate/Gpr81 signaling pathway
Exercise increases bone mass by lactate/Gpr81 signaling pathway Open
Exercise is an effective intervention to promote bone mass by regulating bone homeostasis, but the specific mechanism is ambiguous. Here this study shows that high-intensity interval training (HIIT) was more effective than low-intensity co…
View article: 240 WAY-102: an <i>in vivo</i> lentiviral dual-armored CLDN18.2 CAR T engineered for long-term durability & cytotoxicity in the tumor microenvironment
240 WAY-102: an <i>in vivo</i> lentiviral dual-armored CLDN18.2 CAR T engineered for long-term durability & cytotoxicity in the tumor microenvironment Open
View article: Exogenous activation of the adhesion GPCR ADGRD1/GPR133 protects against bone loss by negatively regulating osteoclastogenesis
Exogenous activation of the adhesion GPCR ADGRD1/GPR133 protects against bone loss by negatively regulating osteoclastogenesis Open
Adhesion G protein–coupled receptors (GPCRs) play crucial roles in numerous physiological and pathological conditions. However, the functions of adhesion GPCRs remain poorly understood because of the lack of effective modulators. Here, we …
View article: Associations between long-term particulate matter exposure and various metabolic syndrome components: Evidence from a prospective cohort study in Eastern China
Associations between long-term particulate matter exposure and various metabolic syndrome components: Evidence from a prospective cohort study in Eastern China Open
View article: Development of an evaluation index system for inappropriate hospital admissions after colorectal cancer surgery in the context of enhanced recovery after surgery
Development of an evaluation index system for inappropriate hospital admissions after colorectal cancer surgery in the context of enhanced recovery after surgery Open
The evaluation index system for ineffective hospital days in postoperative colorectal cancer patients, constructed based on AEP standards within the context of ERAS, demonstrates both scientific rigor and practical applicability. It holds …
View article: GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147
GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147 Open
View article: Superficial temporal artery-to-middle cerebral artery side-to-side microvascular anastomosis using the in-situ intraluminal suturing technique
Superficial temporal artery-to-middle cerebral artery side-to-side microvascular anastomosis using the in-situ intraluminal suturing technique Open
STA-MCA side-to-side microvascular anastomosis with a 4-5 mm long arteriotomy using the in situ intraluminal suturing technique is a safe and effective revascularization surgery, and the anastomosis can serve as a shunt for blood flow self…
View article: Selenium in cancer management: exploring the therapeutic potential
Selenium in cancer management: exploring the therapeutic potential Open
Selenium (Se) is important and plays significant roles in many biological processes or physiological activities. Prolonged selenium deficiency has been conclusively linked to an elevated risk of various diseases, including but not limited …
View article: Physiological and Multi-Omics Integrative Analysis Provides New Insights into Tolerance to Waterlogging Stress in Sesame (Sesamum indicum L.)
Physiological and Multi-Omics Integrative Analysis Provides New Insights into Tolerance to Waterlogging Stress in Sesame (Sesamum indicum L.) Open
Plant growth and development require water, but excessive water hinders growth. Sesame (Sesamum indicum L.) is an important oil crop; it is drought-tolerant but sensitive to waterlogging, and its drought tolerance has been extensively stud…
View article: Impact of menopausal status on cognitive function in female papillary thyroid carcinoma patients: a longitudinal propensity score matched study
Impact of menopausal status on cognitive function in female papillary thyroid carcinoma patients: a longitudinal propensity score matched study Open
View article: Corrigendum to ‘JD-312 – A novel small molecule that facilitates cartilage repair and alleviates osteoarthritis progression’[Journal of Orthopaedic Translation 44 (2024) 60–71]
Corrigendum to ‘JD-312 – A novel small molecule that facilitates cartilage repair and alleviates osteoarthritis progression’[Journal of Orthopaedic Translation 44 (2024) 60–71] Open
View article: The Risk of Cervical Cancer in Women Among Han, Bai, Dai and Hani Ethnic Minorities in Yunnan Province of China
The Risk of Cervical Cancer in Women Among Han, Bai, Dai and Hani Ethnic Minorities in Yunnan Province of China Open
Risk of high parity with cervical cancer could be due to a complex interplay of factors, it is very important to formulate prevention strategies and measures in line with the cervical cancer of Han, Bai, Dai and Hani ethnic groups women in…
View article: Persistent Coma from Contrast-Induced Encephalopathy Following Stent-Assisted Coiling Intracranial Aneurysm: A Case Report
Persistent Coma from Contrast-Induced Encephalopathy Following Stent-Assisted Coiling Intracranial Aneurysm: A Case Report Open
Department of Neurosurgery, Dushu Lake Hospital Affiliated to Soochow University, Suzhou, Jiangsu, China Address for correspondence: Dr. Yulun Huang, Department of Neurosurgery, Dushu Lake Hospital Affiliated to Soochow University, Suzhou …
View article: Survival analysis of palliative radiotherapy in patients with HER-2+ metastatic breast cancer
Survival analysis of palliative radiotherapy in patients with HER-2+ metastatic breast cancer Open
Background Whether radiotherapy can improve the long-term survival of HER-2+ metastatic breast cancer remains unclear. We launched this study to explore the effect of HER-2+ metastatic breast cancer patients through anti-HER-2 targeted the…
View article: JD-312 – A novel small molecule that facilitates cartilage repair and alleviates osteoarthritis progression
JD-312 – A novel small molecule that facilitates cartilage repair and alleviates osteoarthritis progression Open
Together, our findings demonstrate that JD-312 is a promising new therapeutic molecule for cartilage regeneration with clinical potential.
View article: Renal pelvis sarcomatoid carcinoma with renal vein tumor thrombus: A case report and literature review
Renal pelvis sarcomatoid carcinoma with renal vein tumor thrombus: A case report and literature review Open
Type 2 diabetes mellitus (T2DM), which is distinguished by increased glucose levels in the bloodstream, is a metabolic disease with a rapidly increasing incidence worldwide. Nevertheless, the etiology and characteristics of the mechanism o…
View article: P2.05-10 The Power for PD-L1 Expression to Predict Immune Checkpoint Blockade Outcomes is Determined by Tumor Transcriptome
P2.05-10 The Power for PD-L1 Expression to Predict Immune Checkpoint Blockade Outcomes is Determined by Tumor Transcriptome Open
View article: Serum Protein-Based Profiles for the Diagnostic Model of Alzheimer’s Disease
Serum Protein-Based Profiles for the Diagnostic Model of Alzheimer’s Disease Open
Background Determining a non-invasive, serum-based diagnostic panel for early diagnosis of AD will play a significant role in the prevention and treatment of the disease. Methods We performed standardized clinical assessments and neuroimag…
View article: <i>Mycobacterium tuberculosis</i> Rv2653 Protein Promotes Inflammation Response by Enhancing Glycolysis
<i>Mycobacterium tuberculosis</i> Rv2653 Protein Promotes Inflammation Response by Enhancing Glycolysis Open
Mycobacterium tuberculosis (M.tb) infection causes the communicable disease tuberculosis (TB), a major disease and one of the leading causes of death worldwide. The protein encoded by the region of deletion (RD) in M.tb mediates the pathog…
View article: Evaluating the Performance of Large Language Models on GAOKAO Benchmark
Evaluating the Performance of Large Language Models on GAOKAO Benchmark Open
Large Language Models(LLMs) have demonstrated remarkable performance across various natural language processing tasks; however, how to comprehensively and accurately assess their performance becomes an urgent issue to be addressed. This pa…
View article: Identification of DNA repair gene signature and potential molecular subtypes in hepatocellular carcinoma
Identification of DNA repair gene signature and potential molecular subtypes in hepatocellular carcinoma Open
DNA repair is a critical factor in tumor progression as it impacts tumor mutational burden, genome stability, PD-L1 expression, immunotherapy response, and tumor-infiltrating lymphocytes (TILs). In this study, we present a prognostic model…
View article: GPRC5B protects osteoarthritis by regulation of autophagy signaling
GPRC5B protects osteoarthritis by regulation of autophagy signaling Open
Osteoarthritis (OA) is one of the most common chronic diseases in the world. However, current treatment modalities mainly relieve pain and inhibit cartilage degradation, but do not promote cartilage regeneration. In this study, we show tha…
View article: The serum creatinine to cystatin C ratio predicts the risk of acute exacerbation of chronic obstructive pulmonary disease
The serum creatinine to cystatin C ratio predicts the risk of acute exacerbation of chronic obstructive pulmonary disease Open
The purpose of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) treatment is to minimize the negative impact of the current exacerbation and to prevent the development of subsequent events. Therefore, it is important to…
View article: High expression of ABCF1 is an independent predictor of poor prognosis in bladder cancer
High expression of ABCF1 is an independent predictor of poor prognosis in bladder cancer Open
View article: Establishing an RNA fusions panel in soft tissue sarcoma with clinical validation
Establishing an RNA fusions panel in soft tissue sarcoma with clinical validation Open
The diagnosis and classification of soft tissue sarcomas (STS) remain challenging because of the rarity and overlapping morphologic manifestations of diverse STS subtypes. Characteristic gene fusions are commonly detected in STS and repres…
View article: Ecological Restoration Declined the Rainstorm—Flood Relationship for past 40 years on Chinese Loess Plateau
Ecological Restoration Declined the Rainstorm—Flood Relationship for past 40 years on Chinese Loess Plateau Open
The Loess Plateau has been experiencing large-scale ecological construction over the past 40 years. The watershed of Zhou River (1334 km2 ) in the core land of the Loess Plateau was chosen as a case study to …
View article: Knowledge about Plant Coexistence during Vegetation Succession for Forest Management on the Loess Plateau, China
Knowledge about Plant Coexistence during Vegetation Succession for Forest Management on the Loess Plateau, China Open
Coexistence between species within plant communities is a key issue in the practice of revegetation, forest management, and biodiversity conservation. Vegetation restoration is critical to control soil erosion and improve the ecological en…
View article: Detecting the future impact of the "Grain for Green" program on land use/ land cover and hydrological regimes in a watershed of the Chinese Loess Plateau
Detecting the future impact of the "Grain for Green" program on land use/ land cover and hydrological regimes in a watershed of the Chinese Loess Plateau Open
To increase vegetation coverage and improve ecosystem services, the government has promulgated and implemented the program of "Grain for Green" from 1999 to the present. How and where vegetation cover increases and how land u…
View article: Machine learning-based model for predicting the outcome of abdominal paracentesis drainage
Machine learning-based model for predicting the outcome of abdominal paracentesis drainage Open
Background Abdominal Paracentesis drainage (APD) is a useful treatment for acute pancreatitis (AP) patient with pancreatitis associated ascitic fluid, however, researches seldom mentioned whether every patient benefit from this treatment. …