Lingyin Hu
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View article: Mitochondrial DHODH regulates hypoxia-inducible factor 1 expression in OTSCC.
Mitochondrial DHODH regulates hypoxia-inducible factor 1 expression in OTSCC. Open
Oral tongue squamous cell carcinoma (OTSCC) was one of the most hypoxic tumors with unfavorable outcomes. Hypoxia-inducible factor-1 (HIF-1) signaling was associated with cancer proliferation, lymph node metastasis, angiogenesis and poor p…
View article: The functional role of NGFR in regulating chemosensitivity in nasopharyngeal carcinoma
The functional role of NGFR in regulating chemosensitivity in nasopharyngeal carcinoma Open
Background: Nasopharyngeal carcinoma (NPC) is the most common head and neck cancer in southern China. Induction chemotherapy and concurrent chemo-radiation are major treatment methods for advanced NPC patients. However, patients will devel…
View article: The tumorigenic functions of NADPH oxidase 5 (NOX5) in oral tongue squamous cell carcinoma
The tumorigenic functions of NADPH oxidase 5 (NOX5) in oral tongue squamous cell carcinoma Open
Background: Oral tongue squamous cell carcinoma (OTSCC) is a common form of head and neck cancer. According to the data retrieved from Hong Kong Cancer Registry, there is a 48% increase in oral tongue cancer in our locality during the 10-y…