Linjun Shi
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Efficacy and safety of periodontal initial therapy combined with intralesional betamethasone sodium phosphate injection under local anesthesia in managing erosive oral lichen planus: study protocol for a multi-center, split-mouth, randomized self-controlled trial Open
1.0 Version date: 01 September 2025.
Ten-year trend of dental emergency visits in China: a cross-sectional study Open
This study provides a comprehensive overview of dental emergency visits to China's largest center and highlights a substantial increase in cases during holidays, particularly the National Day Holiday. These findings support the need for op…
A Study on the Serum Levels of POSTN and VEGF in Rheumatoid Arthritis Patients and Their Correlations Open
Aims/Background Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, pannus formation, and neovascularization. Reliable biomarkers for monitoring RA activity are needed to optimize treatment str…
Ten-year trend of dental emergency visits in China: A cross-sectional study Open
Background: The demand for dental emergency services has increased in recent years, creating an imbalance between the supply and demand of dental emergency services. To investigate the current status of dental emergency resources and to pr…
Effect of a multidisciplinary team intervention program for older adults with osteoporosis in the community: A randomized controlled trial Open
Background: Limited evidence exists regarding the benefits of interventions for community-dwelling older adults with osteoporosis in China. Aims：This study aims to evaluate the effects of a multidisciplinary team intervention program on th…
A scientometric study on research trends and characteristics of Behçet's disease Open
This scientometric study elucidated the current scenario and research trends of BD, and would help in improving in reciprocal collaboration and communication for investigations on this disease.
Corrigendum: Evaluation of the correlation between depression and physical activity among older persons with osteoporosis: a cross-sectional study Open
[This corrects the article DOI: 10.3389/fpsyt.2023.1193072.].
Evaluation of neck control strategies for oral squamous cell carcinoma of stage I: Neck dissection or potential immunotherapy Open
The neck control strategies of early-stage oral squamous cell carcinoma (OSCC) patients with clinical node-negative neck remain uncertain. These patients could be benefit from elective neck dissection (END) alongside primary tumor excision…
Whether early-stage (N0 neck) oral cancer patients received primary tumor resection without neck dissection benefit from immune checkpoint therapy Open
Highlights For early-stage oral cancer patients with N0 neck, the therapeutic benefit of neck dissection remains uncertain. Increasing evidence indicates that tumor-draining lymph nodes (LNs) are essential sites for responses to immune che…
Evaluation of the correlation between depression and physical activity among older persons with osteoporosis: a cross-sectional study Open
Background Osteoporosis is a common chronic disease in older persons. Physical activity can prevent chronic diseases as well as many diseases associated with aging. Older persons often suffer from depression and other psychological problem…
The implications of nanodiagnostics and artificial intelligence for detecting oral potentially malignant disorders and oral squamous cell carcinoma Open
Liu, Wei MD; Wang, Yizhou DDS; Yang, Xi MD; Shen, Xuemin DMD; Shi, Linjun DMD Author Information
Whether cryosurgery for oral premalignant lesions influences the outcome of malignant transformation Open
aDepartment of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Center of Head and Neck Oncology Clinical and Translational Science, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China…
Surgery management of oral cavity premalignancy needs risk stratification and randomized controlled trials Open
aDepartment of Oral Mucosal Diseases, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China bCollege of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Cli…
A scientometric study of betel quid chewing and oral cancer and precancerous lesions with distinct regional characteristic Open
Scientometric analysis is a useful tool that utilizes bibliometric data to measure scientific output of a disease or region in a particular field. In this report, we comprehensively provide bibliometric characteristics of all the papers on…
Dysregulation and implications of lncRNAs and miRNAs in oral tongue squamous cell carcinoma: In reply with emphasis on the role of ceRNAs Open
Increasing evidence indicates that long noncoding RNAs (lncRNAs) as competing endogenous RNAs (ceRNAs) competitively sequestering microRNAs (miRNAs) participate in biological processes of oral tongue squamous cell carcinoma (TSCC). In this…
LncRNA IFITM4P promotes immune escape by up-regulating PD-L1 via dual mechanism in oral carcinogenesis Open
Oral squamous cell carcinoma (OSCC), which is typically preceded by oral leukoplakia (OL), is a common malignancy with poor prognosis. However, the signaling molecules governing this progression remain to be defined. Based on microarray an…
Evaluation of the Correlation Between Depression and Physical Activity Among Elderly Patients with Osteoporosis: A Cross-Sectional Study Open
Background: Depression and osteoporosis are two chronic diseases that affect many people and have a significant impact on incidence, mortality, and quality of life. An association between osteoporosis and depression has been described in t…
Periodontal initial therapy combined with laterally positioned flap in gingival plasma cell granuloma treatment: a case report Open
Background: Gingival plasma cell granuloma (GPCG) is a rare benign, reactive, non-neoplastic lesion characterized by the predominance of polyclonal plasma cells. Clinical diagnosis is often confused with peripheral giant cell lesion, plasm…
Transcriptome array screening and verification of oral leukoplakia carcinogenesis-related hypoxia-responsive gene and microRNA. Open
The hypoxia response gene and related miRNA play roles in the development and progression of OLK.
Development and validation of a risk model for noninvasive detection of cancer in oral potentially malignant disorders using DNA image cytometry Open
This large-scale diagnostic study established a risk model based on DNA aneuploidy that consisted of a noninvasive strategy with lateral/ventral tongue and non-homogenous features. The results showed favorable diagnostic efficacy for detec…
Comparative Analyses of the Subgingival Microbiome in Chronic Periodontitis Patients with and without Gingival Erosive Oral Lichen Planus Based on 16S rRNA Gene Sequencing Open
The aim of the study was to compare the microbiota composition and bacterial diversity of subgingival plaque in chronic periodontitis patients with and without gingival erosive oral lichen planus. The subgingival plaque samples of 20 chron…
DNA aneuploidy with image cytometry for detecting dysplasia and carcinoma in oral potentially malignant disorders: A prospective diagnostic study Open
Background Current evidence on diagnostic value of aneuploidy with DNA image cytometry (ICM) using brushings for oral potentially malignant disorders (OPMD) is limited by sample size and inconsistent classification criteria of aneuploidy. …
MicroRNA-134 inhibits tumor stem cell migration and invasion in oral squamous cell carcinomas via downregulation of PI3K-Akt signaling pathway by inhibiting LAMC2 expression Open
BACKGROUND: Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the mouth. Some studies have found that multiple microRNAs (miRs) participate in OSCC physiological and pathological processes. METHODS: We explored t…