Li Huang
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View article: A commentary on “DeepSeek-R1 and GPT-4 are comparable in a complex diagnostic challenge: a historical control study”
A commentary on “DeepSeek-R1 and GPT-4 are comparable in a complex diagnostic challenge: a historical control study” Open
View article: Comparative analysis of transcriptomes and hormonal levels in fruit setting induced by GA4+7 and pollination in Cucumis melo L․
Comparative analysis of transcriptomes and hormonal levels in fruit setting induced by GA4+7 and pollination in Cucumis melo L․ Open
View article: The chaperone DnaK promotes the emergence and accumulation of antibiotic-resistant clones through its ATPase activity in Riemerella anatipestifer
The chaperone DnaK promotes the emergence and accumulation of antibiotic-resistant clones through its ATPase activity in Riemerella anatipestifer Open
The rapid emergence of antibiotic-resistant bacteria has become a global concern. In particular, the overuse of antibiotics in the breeding industry has accelerated the emergence of antibiotic-resistant bacteria, but the mechanisms driving…
View article: <i>CHROMOMETHYLASE3</i> governs male fertility to affect seed production in tomato
<i>CHROMOMETHYLASE3</i> governs male fertility to affect seed production in tomato Open
To produce mature seed, flowering plants must undergo successful male and female gametogenesis and pollination followed by fruit set, growth, and ripening. This sequential process involves complex genetic programming and less understood ep…
View article: Functional characterization of the chaperone DnaK of Riemerella anatipestifer in antibiotic resistance and pathogenicity
Functional characterization of the chaperone DnaK of Riemerella anatipestifer in antibiotic resistance and pathogenicity Open
Antibiotic resistance has become a global public health problem, which is closely related to humans, animals and the environment. Riemerella anatipestifer (R. anatipestifer, RA) is a Gram-negative, multi-resistant bacterium that infects du…
View article: Auxin-induced WRKY23 activates PECTIN LYASE-LIKE1 and PECTIN LYASE-LIKE3 for apoplastic iron reutilization in Arabidopsis roots
Auxin-induced WRKY23 activates PECTIN LYASE-LIKE1 and PECTIN LYASE-LIKE3 for apoplastic iron reutilization in Arabidopsis roots Open
The retention and reutilization of apoplastic iron (Fe) are essential for Fe homeostasis in plants, yet the underlying molecular mechanisms remain largely unexplored. Here, we characterized the role of WRKY23, a nucleus-localized transcrip…
View article: Identification and utilization of a novel major QTL and linked markers for enhancing protein content in peanut
Identification and utilization of a novel major QTL and linked markers for enhancing protein content in peanut Open
Peanut is a vital source of protein for humans, playing a key role in maintaining a steady protein supply. In this study, the high protein cultivar Zhonghua6 (29.14±1.69%) was crossed with Xuhua13 (24.55±1.84%) to construct a recombinant i…
View article: Identification and Characterization of Histone Modification Gene Families and Their Expression Patterns During Pod and Seed Development in Peanut
Identification and Characterization of Histone Modification Gene Families and Their Expression Patterns During Pod and Seed Development in Peanut Open
Histone methylation and acetylation play potential roles in plant growth and development through various histone modification (HM) genes. However, studies of HM genes are still limited in peanut (Arachis hypogaea L.), a globally important …
View article: Optimizing Pollen Germination and Egcg-Mediated Subcellular Dynamics in the Pollen Tubes of Camellia Oleifera
Optimizing Pollen Germination and Egcg-Mediated Subcellular Dynamics in the Pollen Tubes of Camellia Oleifera Open
View article: Domestication history and genetic changes for the newly evolved flower color in the ornamental plant <i>Lobularia maritima</i> (Brassicaceae)
Domestication history and genetic changes for the newly evolved flower color in the ornamental plant <i>Lobularia maritima</i> (Brassicaceae) Open
Lobularia maritima (sweet alyssum) is a popular ornamental plant that displays a range of flower colors, particularly white and purple. However, the genetic underpinning and evolutionary history of flower colors have remained unknown. To a…
View article: BcAHL24-MF1 promotes photomorphogenesis in Brassica campestris via inhibiting over-elongation of hypocotyl under light conditions
BcAHL24-MF1 promotes photomorphogenesis in Brassica campestris via inhibiting over-elongation of hypocotyl under light conditions Open
View article: Identification and Functional Exploration of BraGASA Genes Reveal Their Potential Roles in Drought Stress Tolerance and Sexual Reproduction in Brassica rapa L. ssp. pekinensis
Identification and Functional Exploration of BraGASA Genes Reveal Their Potential Roles in Drought Stress Tolerance and Sexual Reproduction in Brassica rapa L. ssp. pekinensis Open
Gibberellic acid-stimulated Arabidopsis sequences (GASAs) are a subset of the gibberellin (GA)-regulated gene family and play crucial roles in various physiological processes. However, the GASA genes in Brassica rapa have not yet been docu…
View article: Applications of image-guided locoregional transarterial chemotherapy in patients with inoperable colorectal cancer: a review
Applications of image-guided locoregional transarterial chemotherapy in patients with inoperable colorectal cancer: a review Open
With the development of comprehensive treatment, locoregional transarterial chemotherapy has become an alternative conversion therapy, palliative therapy, and neoadjuvant therapy for many solid malignant tumors. Locoregional transarterial …
View article: The synchronous upregulation of a specific protein cluster in the blood predicts both colorectal cancer risk and patient immune status
The synchronous upregulation of a specific protein cluster in the blood predicts both colorectal cancer risk and patient immune status Open
The combined detection of the seven signature molecules in CRC can significantly enhance diagnostic efficiency and serve as a novel index for hematological screening of CRC.
View article: Assessing the efficacy of natural soil biotin on soil quality, microbial diversity, and Rhododendron simsii growth for sustainable landscape architecture
Assessing the efficacy of natural soil biotin on soil quality, microbial diversity, and Rhododendron simsii growth for sustainable landscape architecture Open
Fertilization significantly influences soil quality and its sustainable use in urban garden maintenance. The widespread application of inorganic fertilizers has raised ecological concerns due to their potential environmental impacts. Organ…
View article: Natural soil biotin application activates soil beneficial microorganisms to improve the thermotolerance of Chinese cabbage
Natural soil biotin application activates soil beneficial microorganisms to improve the thermotolerance of Chinese cabbage Open
Chinese cabbage ( Brassica campestris L. syn. B. rapa ), a widely cultivated leafy vegetable, faces significant challenges in annual production due to high-temperature stress, which adversely affects plant weight and quality. The need for …
View article: Identification of <i>YUC</i> genes associated with leaf wrinkling trait in Tacai variety of Chinese cabbage
Identification of <i>YUC</i> genes associated with leaf wrinkling trait in Tacai variety of Chinese cabbage Open
Chinese cabbage ( Brassica campestris L. ssp. chinensis (L.) Makino) stands as a widely cultivated leafy vegetable in China, with its leaf morphology significantly influencing both quality and yield. Despite its agricultural importance, th…
View article: Comparative transcriptome and metabolome analysis revealed diversity in the response of resistant and susceptible rose (Rosa hybrida) varieties to Marssonina rosae
Comparative transcriptome and metabolome analysis revealed diversity in the response of resistant and susceptible rose (Rosa hybrida) varieties to Marssonina rosae Open
Rose black spot disease caused by Marssonina rosae is among the most destructive diseases that affects the outdoor cultivation and production of roses; however, the molecular mechanisms underlying the defensive response of roses to M. rosa…
View article: Transcription Factors and Their Regulatory Roles in the Male Gametophyte Development of Flowering Plants
Transcription Factors and Their Regulatory Roles in the Male Gametophyte Development of Flowering Plants Open
Male gametophyte development in plants relies on the functions of numerous genes, whose expression is regulated by transcription factors (TFs), non-coding RNAs, hormones, and diverse environmental stresses. Several excellent reviews are av…
View article: Functional characterization of a TerC family protein of <i>Riemerella anatipestifer</i> in manganese detoxification and virulence
Functional characterization of a TerC family protein of <i>Riemerella anatipestifer</i> in manganese detoxification and virulence Open
Manganese (Mn) is an essential element for bacteria, but the overload of manganese is toxic. In a previous study, we showed that the cation diffusion facilitator protein MetA and the resistance-nodulation-division efflux pump MetB are resp…
View article: Functional characterization of two TolC in the resistance to drugs and metals and in the virulence of <i>Riemerella anatipestifer</i>
Functional characterization of two TolC in the resistance to drugs and metals and in the virulence of <i>Riemerella anatipestifer</i> Open
TolC is an outer membrane protein that is responsible for the efflux of multi-substrates in Gram-negative bacteria. Riemerella anatipestifer CH-1 encodes two TolC proteins, B739_0871 (TolCA) and B739_1784 (TolCB). TolCB was previously invo…
View article: Explorative Gradient Method-Based Research on the Optimization of Nozzle Flow-guiding Devices
Explorative Gradient Method-Based Research on the Optimization of Nozzle Flow-guiding Devices Open
Low-frequency buffeting is a common problem in automobile wind tunnels, it induces pulsations of pressure and velocity in the test section. A 1:15 3/4 open-jet return-type scaled wind tunnel was used for this research, and numerical simula…
View article: Identification and fine mapping of Brmmd1 gene controlling recessive genic male sterility in Brassica rapa L.
Identification and fine mapping of Brmmd1 gene controlling recessive genic male sterility in Brassica rapa L. Open
Recessive genic male sterility (RGMS) provides an effective approach for the commercial exploitation of heterosis, especially in Brassicacrops. Although some artificial RGMS mutants have been reported in B. rapa, no causal genes derived fr…
View article: CG hypermethylation of the <i>bHLH39</i> promoter regulates its expression and Fe deficiency responses in tomato roots
CG hypermethylation of the <i>bHLH39</i> promoter regulates its expression and Fe deficiency responses in tomato roots Open
Iron (Fe) is an essential micronutrient for all organisms, including plants, whose limited bioavailability restricts plant growth, yield, and nutritional quality. While the transcriptional regulation of plant responses to Fe deficiency hav…
View article: Genome-Wide Identification and Expression Analysis of the TIR-NBS-LRR Gene Family and Its Response to Fungal Disease in Rose (Rosa chinensis)
Genome-Wide Identification and Expression Analysis of the TIR-NBS-LRR Gene Family and Its Response to Fungal Disease in Rose (Rosa chinensis) Open
Roses, which are one of the world’s most important ornamental plants, are often damaged by pathogens, resulting in serious economic losses. As a subclass of the disease resistance gene family of plant nucleotide-binding oligomerization dom…
View article: Effects of Microplastic on Human Gut Microbiome: Detection of Plastic-Degrading Genes in Human Gut Exposed to Microplastics—Preliminary Study
Effects of Microplastic on Human Gut Microbiome: Detection of Plastic-Degrading Genes in Human Gut Exposed to Microplastics—Preliminary Study Open
Microplastics are major pollutants in the environment, and it is currently established that microplastics have already entered human food chains and been incorporated into the human body through ingestion and inhalation. Several works in a…
View article: Pre-exposure to Candida albicans induce trans-generational immune priming and gene expression of Musca domestica
Pre-exposure to Candida albicans induce trans-generational immune priming and gene expression of Musca domestica Open
Insects have the phenomenon of immune priming by which they can have enhanced protection against reinfection with the same pathogen, and this immune protection can be passed on to their offspring, which is defined as “trans-generational im…
View article: Highly Overexpressed AtC3H18 Impairs Microgametogenesis via Promoting the Continuous Assembly of mRNP Granules
Highly Overexpressed AtC3H18 Impairs Microgametogenesis via Promoting the Continuous Assembly of mRNP Granules Open
Plant CCCH zinc-finger proteins form a large family of regulatory proteins function in many aspects of plant growth, development and environmental responses. Despite increasing reports indicate that many CCCH zinc-finger proteins exhibit s…
View article: Arabinogalactan Proteins: Focus on the Role in Cellulose Synthesis and Deposition during Plant Cell Wall Biogenesis
Arabinogalactan Proteins: Focus on the Role in Cellulose Synthesis and Deposition during Plant Cell Wall Biogenesis Open
Arabinogalactan proteins (AGPs) belong to a family of glycoproteins that are widely present in plants. AGPs are mostly composed of a protein backbone decorated with complex carbohydrate side chains and are usually anchored to the plasma me…
View article: Biomimetic and Materials-Potentiated Cell Engineering for Cancer Immunotherapy
Biomimetic and Materials-Potentiated Cell Engineering for Cancer Immunotherapy Open
In cancer immunotherapy, immune cells are the main force for tumor eradication. However, they appear to be dysfunctional due to the taming of the tumor immunosuppressive microenvironment. Recently, many materials-engineered strategies are …