Linn Stenfelt
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View article: Glycoproteomic and Phenotypic Elucidation of B4GALNT2 Expression Variants in the SID Histo-Blood Group System
Glycoproteomic and Phenotypic Elucidation of B4GALNT2 Expression Variants in the SID Histo-Blood Group System Open
The Sda histo-blood group antigen (GalNAcβ1-4(NeuAcα2-3)Galβ-R) is implicated in various infections and constitutes a potential biomarker for colon cancer. Sd(a−) individuals (2–4% of Europeans) may produce anti-Sda, which can lead to inco…
View article: The P1PK blood group system: revisited and resolved
The P1PK blood group system: revisited and resolved Open
This update on the P1PK blood group system (Hellberg Å, Westman JS, Thuresson B, Olsson ML. P1PK: the blood group system that changed its name and expanded. Immunohematology 2013;29:25–33) provides recent findings concerning the P1PK blood…
View article: Elucidating Genetic and Biochemical Aspects of the P1 and Sda Carbohydrate Histo-Blood Group Antigens
Elucidating Genetic and Biochemical Aspects of the P1 and Sda Carbohydrate Histo-Blood Group Antigens Open
Human histo-blood groups are inherited polymorphic variants that occur in the molecular structures on the humanred blood cell (RBC) surface. Introducing foreign RBCs into a recipient lacking an antigen may activate the humoraldefence leadi…
View article: Missense mutations in the C-terminal portion of the B4GALNT2-encoded glycosyltransferase underlying the Sd(a−) phenotype
Missense mutations in the C-terminal portion of the B4GALNT2-encoded glycosyltransferase underlying the Sd(a−) phenotype Open
View article: Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT
Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT Open
Key Points The intronic A4GALT SNP rs5751348 defines a hematopoietic transcription factor–binding site present in P1 but not P2 blood group alleles. RUNX1 selectively binds to this regulatory site in P1 alleles; small interfering RNA knock…