Explanipedia

A Research on Preparation and Performance of Volcanogenic Sand Concrete from the Philippines Open

Libo Bian, Jiapeng Bian, Linna Ding, Yangguang Zhao, Haichao Lin , et al. · 2023

The river sand in the Santo Tomas River area of the Philippines is a kind of volcanogenic sand. The sand is fine sand with a fineness modulus of 2.2, an apparent density of 2380 kg/m3, a bulk density of 1320 kg/m3, a mud content of 6.7%, a…

Giant Squamous Cell Carcinoma on The Scalp of A Young African American Male Open

Linna Ding, Bin Yang, Yousef Soofi, G Slawinski · 2021

Introduction/Objective Skin cancer comprises 1-2% of all cancers in African American (AA) patients. Among all skin cancers, squamous cell carcinoma (SCC) is the most common one in AA, with an incidence of approximately 3 per 100,000. It ma…

Phase II Randomized Trial of Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis Open

Yemil Atisha‐Fregoso, Susan Malkiel, Kristina M. Harris, M. Byron, Linna Ding , et al. · 2020

Objective To assess the safety, mechanism of action, and preliminary efficacy of rituximab followed by belimumab in the treatment of refractory lupus nephritis (LN). Methods In a multicenter, randomized, open‐label clinical trial, 43 patie…

178 Phase 2 trial of induction therapy with anti-CD20 (Rituximab) followed by maintenance therapy with anti-BAFF (Belimumab) in patients with active lupus nephritis Open

Cynthia Aranow, Maria Dall’Era, Margaret Byron, Linna Ding, Dawn E. Smilek , et al. · 2019

Background Despite case series suggesting efficacy, controlled trials of anti-CD20 in lupus and lupus nephritis (LN) have not meet their primary endpoints (Arthritis Rheum 2012;64:1215 and 2013;65:2368). A potential explanation is the obse…

Intelligent Design of Belt Edge Damage Online Detection and Positioning System for Conveyors Open

Guangbu Li, Zeng-hui DAI, Linna Ding, Shi Feng-ying · 2019

A scheme of combining single-chip computer with photoelectric sensor, speed sensor and radio frequency identification technology is put forward, aiming at the difficulty of detection and positioning of belt edge damage in long-distance bel…

Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance Open

Simon Glatigny, Barbara Höllbacher, Samantha Motley, Cathy Tan, Christian Hundhausen , et al. · 2019

Abatacept is a CTLA-4-Ig fusion protein that binds to the costimulatory ligands CD80 and CD86 and blocks their interaction with the CD28 and CTLA-4 receptors expressed by T cells, therefore inhibiting T cell activation and function. Abatac…

CT-03 Phase 2 trial of induction therapy with anti-CD20 (rituximab) followed by maintenance therapy with anti-BAFF (belimumab) in patients with active lupus nephritis Open

Cynthia Aranow, Maria Dall’Era, M. Byron, Linna Ding, Dawn E. Smilek , et al. · 2018

Background Despite case series suggesting efficacy, controlled trials of anti-CD20 in lupus nephritis (LN) did not confirm benefit (Arthritis Rheum 2012;64:1215 and 2013;65:2368). Objectives One possible explanation for this failure…

FRI0305 Phase 2 trial of induction therapy with anti-cd20 (RITUXIMAB) followed by maintenance therapy with anti-baff (BELIMUMAB) in patients with active lupus nephritis Open

Cynthia Aranow, Maria Dall’Era, M. Byron, Linna Ding, Dawn E. Smilek , et al. · 2018

The Utility of Urinalysis in Determining the Risk of Renal Relapse in ANCA-Associated Vasculitis Open

Rennie L. Rhee, John C. Davis, Linna Ding, Fernando C. Fervenza, Gary S. Hoffman , et al. · 2018

Background and objectives The significance of persistent hematuria or proteinuria in patients with ANCA-associated vasculitis who are otherwise in clinical remission is unclear. Design, setting, participants, & measurements A post hoc anal…

Correlation of hypogammaglobulinaemia with proteinuria, and the relationship between hypogammaglobulinaemia and infection in active lupus nephritis Open

Dawn E. Smilek, Noha Lim, Linna Ding, Sara G. Murray, Betty Diamond , et al. · 2017

Objective To evaluate hypogammaglobulinaemia and risk of serious infectious adverse events in active lupus nephritis. Methods The Abatacept and Cyclophosphamide Combination Efficacy and Safety Study (ACCESS) compared abatacept with placebo…

ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis Open

Samia J. Khoury, James Rochon, Linna Ding, M. Byron, Kristin Ryker , et al. · 2016

Background: Costimulatory blockade of T lymphocytes with the CTLA4-Ig fusion protein abatacept could be an effective treatment for the immune-mediated neuroinflammatory disease relapsing-remitting multiple sclerosis (RRMS). Objective: To e…

Antithymocyte globulin therapy for patients with recent-onset type 1 diabetes: 2 year results of a randomised trial Open

Stephen E. Gitelman, Peter A. Gottlieb, Eric I. Felner, Steven M. Willi, Lynda K. Fisher , et al. · 2016

Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type Open

Sebastian Unizony, Miguel Villarreal, Eli M. Miloslavsky, Na Lu, Peter A. Merkel , et al. · 2015

Outcomes of Nonsevere Relapses in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Treated With Glucocorticoids Open

Eli M. Miloslavsky, Ulrich Specks, Peter A. Merkel, Philip Seo, Robert Spiera , et al. · 2015

Objective Nonsevere relapses are more common than severe relapses in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV), but their clinical course and treatment outcomes remain largely unexamined. We undertook this stud…

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