Linxia Wu
YOU?
Author Swipe
View article: Prognostic value of body composition on early recurrence and long-term survival of resectable pancreatic ductal adenocarcinoma
Prognostic value of body composition on early recurrence and long-term survival of resectable pancreatic ductal adenocarcinoma Open
Objective To explore the associations of CT-evaluated body composition with early recurrence (ER) and overall survival (OS) in patients with pancreatic ductal adenocarcinoma (PDAC) after resection. Materials and methods A retrospective ana…
View article: Constructing datasets and training deep networks for the direct apoptotic cell identification from H&E staining images
Constructing datasets and training deep networks for the direct apoptotic cell identification from H&E staining images Open
Background Hematoxylin and eosin (H&E) staining is a simple and cost-effective method that can also be used to detect apoptotic cells, but even experienced pathologists often struggle to accurately identifying apoptotic cells using H&E tis…
View article: Interpretable machine learning model for predicting early recurrence of pancreatic cancer: integrating intratumoral and peritumoral radiomics with body composition
Interpretable machine learning model for predicting early recurrence of pancreatic cancer: integrating intratumoral and peritumoral radiomics with body composition Open
Background: Pancreatic ductal adenocarcinoma (PDAC) is associated with a high rate of early recurrence (ER) after radical resection, which significantly affects long-term survival. Currently, no reliable system exists for predicting ER in …
View article: Quantitative Evaluation of Acute Pancreatitis Based on Dual-Energy Computed Tomography
Quantitative Evaluation of Acute Pancreatitis Based on Dual-Energy Computed Tomography Open
Objective: To evaluate the value of dual-energy computed tomography (DECT) parameters for the quantitative diagnosis of acute pancreatitis (AP) and classification of its severity. Methods: Patients with AP underwent a plain CT scan and thr…
View article: Effect of metformin on hepatocellular carcinoma patients with type II diabetes receiving transarterial chemoembolization: a multicenter retrospective cohort study
Effect of metformin on hepatocellular carcinoma patients with type II diabetes receiving transarterial chemoembolization: a multicenter retrospective cohort study Open
Background: Diabetes is prevalent among patients with hepatocellular carcinoma (HCC) and is associated with a poor prognosis. Although the hypoglycemic drug metformin has shown antitumor effects, its potential positive effect on patients w…
View article: A clinical-radiomics nomogram based on dual-layer spectral detector CT to predict cancer stage in pancreatic ductal adenocarcinoma
A clinical-radiomics nomogram based on dual-layer spectral detector CT to predict cancer stage in pancreatic ductal adenocarcinoma Open
Background This study aimed to evaluate the efficacy of radiomics signatures derived from polyenergetic images (PEIs) and virtual monoenergetic images (VMIs) obtained through dual-layer spectral detector CT (DLCT). Moreover, it sought to d…
View article: Autophagy‐related 5 in acute ischemic stroke: Variation and linkage with neurofunction, and survival
Autophagy‐related 5 in acute ischemic stroke: Variation and linkage with neurofunction, and survival Open
Objective Autophagy‐related 5 (ATG5) facilitates the pathologic process of acute ischemic stroke (AIS) via multiple ways. This study aimed to identify the association of serum ATG5 with clinical outcomes in AIS patients. Methods Serum ATG5…
View article: Long-term radiological and pulmonary function abnormalities at 3 years after COVID-19 hospitalisation: a longitudinal cohort study
Long-term radiological and pulmonary function abnormalities at 3 years after COVID-19 hospitalisation: a longitudinal cohort study Open
Background This study aimed to evaluate the longitudinal progression of residual lung abnormalities (ground-glass opacities, reticulation and fibrotic-like changes) and pulmonary function at 3 years following coronavirus disease 2019 (COVI…
View article: Serum autophagy-related gene 5 level in stroke patients: correlation with CD4+ T cells and cognition impairment during a 3-year follow-up
Serum autophagy-related gene 5 level in stroke patients: correlation with CD4+ T cells and cognition impairment during a 3-year follow-up Open
Autophagy-related gene (ATG) 5 regulates blood lipids, chronic inflammation, CD4+ T-cell differentiation, and neuronal death and is involved in post-stroke cognitive impairment. This study aimed to explore the correlation of serum ATG5 wit…
View article: Geographical Indication Characteristics of Aroma and Phenolic Acids of the Changping Strawberry
Geographical Indication Characteristics of Aroma and Phenolic Acids of the Changping Strawberry Open
Strawberry is the most consumed berry fruit worldwide due to its unique aroma and high nutritive value. This fruit is also an important source of phenolic compounds. Changping strawberries are recognized as a national agricultural product …
View article: Is disease activity associated with social support and psychological distress in Crohn’s disease patients? Results of a cross-sectional study in a Chinese hospital population
Is disease activity associated with social support and psychological distress in Crohn’s disease patients? Results of a cross-sectional study in a Chinese hospital population Open
Objectives This study aims to assess the relative of social support and psychological distress in disease activity among patients with Crohn’s disease (CD) in China, and explore whether sex moderates the relationship between disease activi…
View article: Clinical-radiomics nomogram using contrast-enhanced CT to predict histological grade and survival in pancreatic ductal adenocarcinoma
Clinical-radiomics nomogram using contrast-enhanced CT to predict histological grade and survival in pancreatic ductal adenocarcinoma Open
Objectives Tumor grading is important for prognosis of pancreatic ductal adenocarcinoma (PDAC). In this study, we developed preoperative clinical-radiomics nomograms using features from contrast-enhanced CT (CECT), to discriminate high-gra…
View article: Clinical-radiomics-based treatment decision support for KIT Exon 11 deletion in gastrointestinal stromal tumors: a multi-institutional retrospective study
Clinical-radiomics-based treatment decision support for KIT Exon 11 deletion in gastrointestinal stromal tumors: a multi-institutional retrospective study Open
Objective gastrointestinal stromal tumors (GISTs) with KIT exon 11 deletions have more malignant clinical outcomes. A radiomics model was constructed for the preoperative prediction of KIT exon 11 deletion in GISTs. Methods Overall, 126 pa…
View article: Differential Diagnosis of Adrenal Adenomas and Metastases Using Spectral Parameters in Dual-layer Detector Spectral CT
Differential Diagnosis of Adrenal Adenomas and Metastases Using Spectral Parameters in Dual-layer Detector Spectral CT Open
Objective To assess the diagnostic value of spectral parameters in differentiating adrenal adenomas from metastases based on dual-layer detector spectral CT (DLSCT). Materials and methods Patients with adenomas or metastases who underwent …
View article: Comparative Metabolomic Analysis of the Nutritional Aspects from Ten Cultivars of the Strawberry Fruit
Comparative Metabolomic Analysis of the Nutritional Aspects from Ten Cultivars of the Strawberry Fruit Open
Strawberry (Fragaria × ananassa) is among the most widely cultivated fruits with good taste and rich nutrients. Many strawberry species, including white strawberries, are planted all over the world. The metabolic profiles of strawberry and…
View article: The Effect of Alcohol Consumption in Unresectable Hepatocellular Carcinoma with Transarterial Chemoembolization
The Effect of Alcohol Consumption in Unresectable Hepatocellular Carcinoma with Transarterial Chemoembolization Open
Background. Alcohol consumption can increase the risk of developing hepatocellular carcinoma (HCC). However, whether continuous alcohol consumption can influence outcomes in patients with HCC who undergo transarterial chemoembolization (TA…
View article: The Effects of Radiotherapy on Pancreatic Ductal Adenocarcinoma in Patients with Liver Metastases
The Effects of Radiotherapy on Pancreatic Ductal Adenocarcinoma in Patients with Liver Metastases Open
Background: While radiotherapy has been studied in the treatment of locally advanced pancreatic ductal adenocarcinoma (PDAC), few studies have analyzed the effects of radiotherapy on PDAC in patients with liver metastases. This study aimed…
View article: The Efficacy and Safety of Transarterial Chemoembolization Plus Iodine 125 Seed Implantation in the Treatment of Hepatocellular Carcinoma With Oligometastases: A Case Series Reports
The Efficacy and Safety of Transarterial Chemoembolization Plus Iodine 125 Seed Implantation in the Treatment of Hepatocellular Carcinoma With Oligometastases: A Case Series Reports Open
Background Patients with different primary tumor oligometastases can obtain survival benefits from external radiotherapy. The study was conducted to explore the efficacy and safety of transarterial chemoembolization (TACE) plus iodine 125 …
View article: Alterations of Regional Homogeneity in Crohn's Disease With Psychological Disorders: A Resting-State fMRI Study
Alterations of Regional Homogeneity in Crohn's Disease With Psychological Disorders: A Resting-State fMRI Study Open
Abnormal psychological processing in the central nervous system has been found in Crohn's disease (CD) patients. Resting-state functional magnetic resonance images of 57 inactive and 58 active CD patients, and 92 healthy controls (HC) were…
View article: The trends and efficacy of operation in the treatment of hepatocellular carcinoma
The trends and efficacy of operation in the treatment of hepatocellular carcinoma Open
Although surgery rate declined from 2004 to 2015 in all HCC patients, it might be used more widely in patients with localized and regional tumors. And the treatment of surgery in patients with single tumor larger than 5 cm or patients with…
View article: Comparison of the efficacy of radiofrequency ablation vs. liver resection in the treatment of hepatocellular carcinoma within Milan criteria with severe fibrosis
Comparison of the efficacy of radiofrequency ablation vs. liver resection in the treatment of hepatocellular carcinoma within Milan criteria with severe fibrosis Open
Background The efficacy of RFA in the treatment of HCC with severe fibrosis is still unclear. The objective of this study is to compare the efficacy of RFA with liver resection in the treatment of HCC within Milan criteria. Methods The dat…
View article: The Efficacy of Transarterial Chemoembolization plus Apatinib or Sorafenib in the Treatment of Advanced Hepatocellular Carcinoma
The Efficacy of Transarterial Chemoembolization plus Apatinib or Sorafenib in the Treatment of Advanced Hepatocellular Carcinoma Open
Background. Transarterial chemoembolization (TACE) combined with sorafenib (TACE-S) or apatinib (TACE-A) is used in the treatment of hepatocellular carcinoma (HCC). However, to date, no study has compared the efficacy and safety of both tr…
View article: Geographical and Varietal Traceability of Chinese Jujubes Based on Physical and Nutritional Characteristics
Geographical and Varietal Traceability of Chinese Jujubes Based on Physical and Nutritional Characteristics Open
Chinese jujube fruits are known for their high nutritional and functional values. To protect advantageous regional jujube fruits, it is important to monitor quality indicators and trace the origin and variety. In this study, 31 quality ind…
View article: Risk Assessment and Prediction of Aflatoxin in Agro-Products
Risk Assessment and Prediction of Aflatoxin in Agro-Products Open
Aflatoxin (AFT), highly toxic and carcinogenic to humans, seriously threatens consumption safety of agro-products. It is necessary to conduct risk assessment of aflatoxin contamination in agro-food products to find out critical control poi…
View article: Tumor suppressive role of miR-569 in lung cancer
Tumor suppressive role of miR-569 in lung cancer Open
microRNAs (miRs) are targets for genomic aberrations and emerging treatments against cancer. It has been demonstrated that targeting miR-569 may potentially benefit patients with ovarian or breast cancer. However, the exact roles of miR-56…
View article: Risk Assessment on Dietary Exposure to Aflatoxin B1 in Post-Harvest Peanuts in the Yangtze River Ecological Region
Risk Assessment on Dietary Exposure to Aflatoxin B1 in Post-Harvest Peanuts in the Yangtze River Ecological Region Open
Based on the 2983 peanut samples from 122 counties in six provinces of China’s Yangtze River ecological region collected between 2009–2014, along with the dietary consumption data in Chinese resident nutrition and health survey reports fro…
View article: Significant association between the MTHFR A1298C polymorphism and hepatocellular carcinoma risk: a meta-analysis
Significant association between the MTHFR A1298C polymorphism and hepatocellular carcinoma risk: a meta-analysis Open
The A1298C polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene has been reported to be associated with hepatocellular carcinoma (HCC), but there are conflicting results from previous studies. The present study aimed to inv…