Linxuan Zou
YOU?
Author Swipe
View article: Unveiling the interplay among skin microbiota, cytokines, and T2DM: an insightful Mendelian randomization study
Unveiling the interplay among skin microbiota, cytokines, and T2DM: an insightful Mendelian randomization study Open
In this study, we found a connection between the skin microbiome and T2DM, with inflammatory cytokines playing a key role in this relationship. This research helps us better understand this complex link and shows that addressing inflammati…
View article: Investigating the causal links between obstructive sleep apnea and gastrointestinal diseases mediated by metabolic syndrome through mendelian randomization
Investigating the causal links between obstructive sleep apnea and gastrointestinal diseases mediated by metabolic syndrome through mendelian randomization Open
Previous studies have pointed to a potential link between Obstructive Sleep Apnea (OSA) and gastrointestinal diseases, suggesting that this relationship might be influenced by the presence of Metabolic Syndrome. However, the exact role of …
View article: The Impact of Toe Amputation on the Quality of Life of Diabetic Foot Patients: A Cardiff Wound Impact Schedule (CWIS) Evaluation
The Impact of Toe Amputation on the Quality of Life of Diabetic Foot Patients: A Cardiff Wound Impact Schedule (CWIS) Evaluation Open
Background: The treatment and management of diabetic foot significantly impact the quality of life (QoL) of patients, yet studies concerning the effects of toe amputation on QoL are relatively limited. Methods: This study included 12 diabe…
View article: Establishment of skin cutaneous melanoma prognosis model based on vascular mimicry risk score
Establishment of skin cutaneous melanoma prognosis model based on vascular mimicry risk score Open
Studies have indicated that Vascular mimicry (VM) could contribute to the unfavorable prognosis of skin cutaneous melanoma (SKCM). Thus, the objective of this study was to identify therapeutic targets associated with VM in SKCM and develop…
View article: Peripheral artery disease mediating the effect of metabolic syndrome related diseases on lower limb ulcers: Mendelian randomization analysis
Peripheral artery disease mediating the effect of metabolic syndrome related diseases on lower limb ulcers: Mendelian randomization analysis Open
Background Previous observational studies have demonstrated a correlation between metabolic syndrome related diseases and an elevated susceptibility to ulcers of lower limb. It has been suggested that this causal relationship may be influe…
View article: Dynamics of Microbial Communities in Chronic Wounds and Their Role in Wound Healing
Dynamics of Microbial Communities in Chronic Wounds and Their Role in Wound Healing Open
Chronic wounds, such as diabetic foot ulcers, pressure sores, and venous stasis ulcers, have long posed a challenge in the medical field.The healing process of these wounds is influenced by various factors, among which the role of the micr…
View article: Identification of ferroptosis-related molecular clusters and genes for diabetic osteoporosis based on the machine learning
Identification of ferroptosis-related molecular clusters and genes for diabetic osteoporosis based on the machine learning Open
Background Diabetic osteoporosis exhibits heterogeneity at the molecular level. Ferroptosis, a controlled form of cell death brought on by a buildup of lipid peroxidation, contributes to the onset and development of several illnesses. The …
View article: Machine learning revealed novel ferroptosis-related genes and construction ceRNA network in dermal lymphatic endothelial cells of diabetic foot ulcer
Machine learning revealed novel ferroptosis-related genes and construction ceRNA network in dermal lymphatic endothelial cells of diabetic foot ulcer Open
Background Diabetic foot ulcer (DFU) is a common chronic and serious complication that impairs patients' quality of life. The relationship between ferroptosis and complications of diabetes has attracted much attention in recent years. Here…
View article: A Cox Nomogram for Assessing Recurrence Free Survival in Hepatocellular Carcinoma Following Surgical Resection Using Dynamic Contrast‐Enhanced MRI Radiomics
A Cox Nomogram for Assessing Recurrence Free Survival in Hepatocellular Carcinoma Following Surgical Resection Using Dynamic Contrast‐Enhanced MRI Radiomics Open
Background The prognosis of hepatocellular carcinoma (HCC) is difficult to predict and carries high mortality. This study utilized radiomic techniques with clinical examinations to assess recurrence in HCC. Purpose To develop a Cox nomogra…
View article: <scp>GluCEST</scp> Imaging and Structural Alterations of the Bilateral Hippocampus in First‐Episode and <scp>Early‐Onset</scp> Major Depression Disorder
<span>GluCEST</span> Imaging and Structural Alterations of the Bilateral Hippocampus in First‐Episode and <span>Early‐Onset</span> Major Depression Disorder Open
Background Glutamate dysregulation is one of the key pathogenic mechanisms of major depressive disorder (MDD), and glutamate chemical exchange saturation transfer (GluCEST) has been used for glutamate measurement in some brain diseases but…
View article: Transcriptome Analysis Reveals Auto-Inflammatory Genes of Chronic Nonbacterial Osteomyelitis (CNO) Based on The Machine Learning
Transcriptome Analysis Reveals Auto-Inflammatory Genes of Chronic Nonbacterial Osteomyelitis (CNO) Based on The Machine Learning Open
Objectives: Chronic nonbacterial osteomyelitis (CNO) is an auto-inflammatory bone disorder. Since the origin and development of CNO involve many complex immune processes, resulting in delayed diagnosis and lack of effective treatment. Alth…
View article: Prediction of the potential Diagnostic Markers of Peripheral Arterial Disease by machine learning and the Correlation with the Ferroptosis and Network of Cancer Gene
Prediction of the potential Diagnostic Markers of Peripheral Arterial Disease by machine learning and the Correlation with the Ferroptosis and Network of Cancer Gene Open
Background: Peripheral arterial disease (PAD) is a widely and complex disease which also known as arteriosclerosis obliterans(ASO). This disorder causes an increasingly prevalence all around the world. Despite its high prevalence and huge …
View article: Screening CEACAM8 and LCN2 as immune-related diagnostic biomarkers after burn to prevent serious complications
Screening CEACAM8 and LCN2 as immune-related diagnostic biomarkers after burn to prevent serious complications Open
Background: Burns are an underrated injury that can affect anyone, anytime and anywhere. Therefore, screening immune-related diagnostic markers of burn can be used to prevent serious complications and death. Methods: GEO database obtains G…
View article: Protective Effect of Homogeneous Polysaccharide from Wuguchong(HPW) on Intestinal Mucositis Induced by 5- Fluorouracil in Mice
Protective Effect of Homogeneous Polysaccharide from Wuguchong(HPW) on Intestinal Mucositis Induced by 5- Fluorouracil in Mice Open
Background: In hospitalized patients, drug side effects usually trigger off intestinal mucositis(IM), which in turn abates intestinal absorption and reduces the efficacy of treatment. It has been discovered that natural polysaccharides can…
View article: The Research Review and Hot Topics Analysis of Work Disruption from an Organizational Perspective
The Research Review and Hot Topics Analysis of Work Disruption from an Organizational Perspective Open
With the advent of the epidemic era and the massive use of information technology in the work environment, task interruptions have become more frequent and unavoidable, which has a significant impact on the work of employees in organizatio…
View article: Brachial-Ankle Pulse Wave Velocity as a Novel Modality for Detecting Early Diabetic Nephropathy in Type 2 Diabetes Patients
Brachial-Ankle Pulse Wave Velocity as a Novel Modality for Detecting Early Diabetic Nephropathy in Type 2 Diabetes Patients Open
Brachial-ankle pulse wave velocity (baPWV) has been shown to correlate with a host of disorders associated with arterial stiffness. Type 2 diabetes is associated with the involvement of both small vessels and large vessels. Studies on the …