Liping Liu
YOU?
Author Swipe
View article: Contact aspiration versus stent retriever thrombectomy for acute basilar artery occlusion (ANGEL-COAST): rationale and design of a multicentre, prospective, randomised, open-label, blinded-endpoint trial
Contact aspiration versus stent retriever thrombectomy for acute basilar artery occlusion (ANGEL-COAST): rationale and design of a multicentre, prospective, randomised, open-label, blinded-endpoint trial Open
Background Contact aspiration (CA) and stent retriever (SR) thrombectomy are two equally recommended first-line endovascular techniques for treating acute ischaemic stroke due to large vessel occlusion. Whether CA is more effective in achi…
View article: C-reactive protein-to-albumin ratio as a predictor of 28-day mortality in critically ill pediatric patients: a retrospective cohort study
C-reactive protein-to-albumin ratio as a predictor of 28-day mortality in critically ill pediatric patients: a retrospective cohort study Open
Objective This large-scale real-world study aimed to evaluate whether the C-reactive protein-to-albumin ratio (CAR), an indicator of systemic inflammation and nutritional status, predicts 28-day mortality in critically ill pediatric patien…
View article: The effect of social support on college students’ sports anomie behavior: the mediating role of self-efficacy and attitude’s regulating role in sports normative behavior
The effect of social support on college students’ sports anomie behavior: the mediating role of self-efficacy and attitude’s regulating role in sports normative behavior Open
Background College students’ sports anomie behavior negatively impacts their physical health, undermines the implementation of the educational philosophies of Fostering Virtue through Education and Health First. There is a lack of quantita…
View article: The impact of iatrogenic atrial septal defect on the prognosis of left atrial appenda ge closure in patients with nonvalvular atrial fibrillation
The impact of iatrogenic atrial septal defect on the prognosis of left atrial appenda ge closure in patients with nonvalvular atrial fibrillation Open
Atrial fibrillation (AF) is a common arrhythmia in clinical practice, and stroke is a serious complication. Left atrial appendage closure (LAAC) is an effective method for preventing thromboembolism in AF patients. During LAAC, transient o…
View article: Treatment beyond progression and rechallenge with pyrotinib in HER2-positive metastatic breast cancer and brain metastases: a multicenter real-world study
Treatment beyond progression and rechallenge with pyrotinib in HER2-positive metastatic breast cancer and brain metastases: a multicenter real-world study Open
Background: Despite significant advancements in treatment, patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) continue to face the challenge of drug resistance, highlighting the need to de…
View article: Cerebral Microbleeds and the Effect of Early Antihypertensive Treatment in Patients with Acute Ischemic Stroke: A Secondary Analysis of the CATIS-2 Trial
Cerebral Microbleeds and the Effect of Early Antihypertensive Treatment in Patients with Acute Ischemic Stroke: A Secondary Analysis of the CATIS-2 Trial Open
Background and Objectives To explore whether the presence, burden or distribution of cerebral microbleeds (CMBs) modifies the effect of early versus delayed antihypertensive treatment on clinical outcomes in acute ischemic stroke (AIS) pat…
View article: Synchronous hepatectomy and splenectomy for patients with BCLC stage 0/A hepatocellular carcinoma and clinically significant portal hypertension: A multicenter retrospective cohort study
Synchronous hepatectomy and splenectomy for patients with BCLC stage 0/A hepatocellular carcinoma and clinically significant portal hypertension: A multicenter retrospective cohort study Open
View article: Dominance of the GI-19 genotype and genomic characterization of the S1 gene in avian infectious bronchitis virus from 2020 to 2024
Dominance of the GI-19 genotype and genomic characterization of the S1 gene in avian infectious bronchitis virus from 2020 to 2024 Open
The continuous emergence of avian infectious bronchitis virus (IBV) variants poses a critical threat to poultry health and productivity in China. In this study, we conducted comprehensive genetic and antigenic analyses of IBV strains isola…
View article: Effect of modified indwelling needle insertion techniques in Chinese children: a systematic review and meta-analysis
Effect of modified indwelling needle insertion techniques in Chinese children: a systematic review and meta-analysis Open
Aim A comprehensive study evaluated the effect of modified indwelling needle technique on puncture success rate and indwelling time in Chinese children. Background Compared with ordinary steel needles, indwelling needles have many advantag…
View article: Interplatform Agreement Between Liver Steatosis Analysis and Ultrasound-Guided Attenuation Parameter in the Evaluation of Hepatic Steatosis
Interplatform Agreement Between Liver Steatosis Analysis and Ultrasound-Guided Attenuation Parameter in the Evaluation of Hepatic Steatosis Open
LiSA and UGAP exhibited excellent interplatform agreement and can be used interchangeably for longitudinal monitoring of patients with hepatic steatosis.
View article: Improvement in renal function after switching from entecavir to tenofovir alafenamide in chronic hepatitis B patients with low estimated glomerular filtration rates
Improvement in renal function after switching from entecavir to tenofovir alafenamide in chronic hepatitis B patients with low estimated glomerular filtration rates Open
There was a substantial difference in eGFR between ETV and TAF treatments at week 48. Gender, baseline eGFR, and medication (TAF/ETV) were all remarkably positive indicators of eGFR abnormalities. In patients receiving ETV, an early switch…
View article: Application and prospects of genetic engineering in CAR-NK cell therapy
Application and prospects of genetic engineering in CAR-NK cell therapy Open
With the rapid advancement of genetic engineering technologies, CAR-NK cell therapy, as an emerging immunotherapeutic approach, has demonstrated significant potential. CAR-NK cells recognize and eliminate tumor cells through chimeric antig…
View article: Colchicine for preventing stroke in patients with and without intracranial atherosclerotic stenosis: a prespecified analysis of a randomized clinical trial
Colchicine for preventing stroke in patients with and without intracranial atherosclerotic stenosis: a prespecified analysis of a randomized clinical trial Open
National Key R&D Program of China, National Natural Science Foundation of China, the Capital's Funds for Health Improvement and Research and Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences. China Kunming Pharmaceut…
View article: Rutin Protects Myocardial Ischemia–Reperfusion Injury via the NF-κB/NLRP3/Pyroptosis Pathway
Rutin Protects Myocardial Ischemia–Reperfusion Injury via the NF-κB/NLRP3/Pyroptosis Pathway Open
This study aimed to determine the protective role and mechanism of rutin on myocardial ischemia-reperfusion (I/R) injury. First, a myocardial I/R injury model was established and subjected to ischemia and hypoxia to simulate the model of I…
View article: Dualistic perspectives on illness coping experiences of individuals with depression and their spouses: a qualitative study
Dualistic perspectives on illness coping experiences of individuals with depression and their spouses: a qualitative study Open
Healthcare professionals should promote positive dyadic coping among individuals with depression and their spouses while caring for depressive illnesses. They should strengthen individuals' knowledge of the disease, attend to spouses' phys…
View article: Impact of <scp>NA</scp>‐1 on Pericyte‐Driven Vasoconstriction and Its Role in No‐Reflow During Cerebral Ischemia–Reperfusion
Impact of <span>NA</span>‐1 on Pericyte‐Driven Vasoconstriction and Its Role in No‐Reflow During Cerebral Ischemia–Reperfusion Open
Background The no‐reflow phenomenon in the ischemic brain following arterial recanalization leads to poor prognosis. Previous studies suggest that the clinically proven NA‐1 drug, with disruption of PSD95 in the neuronal terminals alongsid…
View article: Prognostic significance of contrast staining following mechanical thrombectomy in acute ischaemic stroke
Prognostic significance of contrast staining following mechanical thrombectomy in acute ischaemic stroke Open
Background Advances in endovascular thrombectomy (EVT) and extended treatment criteria have improved outcomes in acute ischaemic stroke (AIS). However, contrast staining (CS) on postoperative CT complicates clinical decision-making and out…
View article: Deciphering the Heterogeneity of Schizophrenia: A Multimodal and Multivariate Neuroimaging Framework for Unveiling Brain-Symptom Relationships and Underlying Subtypes
Deciphering the Heterogeneity of Schizophrenia: A Multimodal and Multivariate Neuroimaging Framework for Unveiling Brain-Symptom Relationships and Underlying Subtypes Open
Background and Hypothesis Schizophrenia manifests large heterogeneities in either symptoms or brain abnormalities. However, the neurobiological basis of symptomatic diversity remains poorly understood. We hypothesized that schizophrenia’s …
View article: E<b>F</b>fects of Y-6 S<b>U</b>blingual Tablets for Pa<b>T</b>ients with Ac<b>U</b>te Ischemic St<b>R</b>ok<b>E</b> (FUTURE): a phase II, randomised, double-blind, double-dummy, placebo-controlled, parallel trial
E<b>F</b>fects of Y-6 S<b>U</b>blingual Tablets for Pa<b>T</b>ients with Ac<b>U</b>te Ischemic St<b>R</b>ok<b>E</b> (FUTURE): a phase II, randomised, double-blind, double-dummy, placebo-controlled, parallel trial Open
Background Acute ischaemic stroke, due to its high mortality and disability rates, imposes a significant economic and social burden worldwide. Typically, endovascular treatment within the therapeutic window is provided to salvage the ischa…
View article: Genetic and neural mechanisms shared by schizophrenia and depression
Genetic and neural mechanisms shared by schizophrenia and depression Open
Schizophrenia (SCZ) and depression are two prevalent mental disorders characterized by comorbidity and overlapping symptoms, yet the underlying genetic and neural mechanisms remain largely elusive. Here, we investigated the genetic variant…
View article: Phylogenetic Analysis and Pathogenicity of Avian Reoviruses Isolated from Viral Arthritis Cases in China 2010–2024
Phylogenetic Analysis and Pathogenicity of Avian Reoviruses Isolated from Viral Arthritis Cases in China 2010–2024 Open
Avian reovirus (ARV) is one of the main causes of viral arthritis, tenosynovitis, malabsorption syndrome (MAS), runting-stunting syndrome, and immunodepression. In recent years, due to the emergence of new ARV strains, outbreaks of the dis…
View article: Rationale and Study Design to Assess the Efficacy and Safety of Minocycline in Patients with Moderate to Severe Acute Ischaemic Stroke (EMPHASIS)
Rationale and Study Design to Assess the Efficacy and Safety of Minocycline in Patients with Moderate to Severe Acute Ischaemic Stroke (EMPHASIS) Open
Background Inflammation and blood-brain barrier disruption may contribute to the pathogenesis of ischaemic stroke. Minocycline was shown to exert anti-inflammatory effects by attenuating microglial activation and protecting blood-brain bar…
View article: Association between hypothermia and hyperthermia and 28-day mortality in pediatric intensive care unit patients: a retrospective cohort study
Association between hypothermia and hyperthermia and 28-day mortality in pediatric intensive care unit patients: a retrospective cohort study Open
Body temperature (BT) monitoring is critical for the management of critically ill patients, and numerous studies have demonstrated that abnormal BT in ICU patients is linked to adverse outcomes. However, evidence regarding the association …
View article: Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes
Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes Open
Importance Few of the available therapies for type 2 diabetes (T2D) comprehensively address disease burden beyond glycemic control. Examining whether berberine ursodeoxycholate (HTD1801), a first-in-class gut-liver anti-inflammatory metabo…
View article: Non-Invasive Kupffer-CEUS Enhances the Accuracy of Focal Liver Lesions Diagnosis in Patients with Liver Cirrhosis or Fibrosis: A Prospective Multicenter Study from China
Non-Invasive Kupffer-CEUS Enhances the Accuracy of Focal Liver Lesions Diagnosis in Patients with Liver Cirrhosis or Fibrosis: A Prospective Multicenter Study from China Open
Introduction: It is challenging to diagnose liver masses in the context of a rough liver background using computed tomography and magnetic resonance imaging. Perfluorobutane CEUS microbubble, an ultrasound (US) contrast agent, has a unique…
View article: Contralateral Neurovascular Coupling in Patients with Ischemic Stroke After Endovascular Thrombectomy
Contralateral Neurovascular Coupling in Patients with Ischemic Stroke After Endovascular Thrombectomy Open
Background Neurovascular coupling (NVC) refers to the process of aligning cerebral blood flow with neuronal metabolic demand. This study explores the potential of contralateral NVC—linking neural electrical activity on the stroke side with…
View article: Analysis of early efficacy and immune reconstitution after autologous hematopoietic stem cell transplantation in multiple myeloma
Analysis of early efficacy and immune reconstitution after autologous hematopoietic stem cell transplantation in multiple myeloma Open
View article: Effect of Tranexamic Acid for Acute Spontaneous Intracerebral Haemorrhage: A Systematic Review and Individual Patient Data Meta-Analysis
Effect of Tranexamic Acid for Acute Spontaneous Intracerebral Haemorrhage: A Systematic Review and Individual Patient Data Meta-Analysis Open
View article: Predictive value of geriatric nutritional risk index in patients with pancreatic cancer: a meta-analysis.
Predictive value of geriatric nutritional risk index in patients with pancreatic cancer: a meta-analysis. Open
Identifier CRD42023409362.
View article: Three-Dimensional Mosaic Method of Dual-Polarization Parameters for a High-Density Radar Network
Three-Dimensional Mosaic Method of Dual-Polarization Parameters for a High-Density Radar Network Open