Liping Meng
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View article: Role of gut microbiota and its metabolites in diabetic cardiomyopathy: from pathogenesis to interventions
Role of gut microbiota and its metabolites in diabetic cardiomyopathy: from pathogenesis to interventions Open
Diabetic cardiomyopathy (DCM), a prevalent cardiovascular complication and the principal driver of mortality among patients with diabetes, represents a significant clinical challenge. The gut microbiota, which reside a complex ecosystem wi…
View article: Impact of social-psychological factors on anxiety before gastrointestinal endoscopy and quality of life
Impact of social-psychological factors on anxiety before gastrointestinal endoscopy and quality of life Open
Introduction This study aimed to examine the impact of social-psychological factors on anxiety before gastrointestinal endoscopy and its effect on patients’ quality of life (QoL). Methods Patients scheduled for gastrointestinal endoscopy w…
View article: Audio-visual crossmodal connectivity in perceiving distorted speech: A comparison between patients with cleft palate and typical listeners
Audio-visual crossmodal connectivity in perceiving distorted speech: A comparison between patients with cleft palate and typical listeners Open
This study investigates audio-visual crossmodal connectivity during the perception of distorted speech using task-based functional magnetic resonance imaging (fMRI). A randomized block design was employed, involving 20 patients with cleft …
View article: Akkermansia muciniphila ameliorates doxorubicin-induced cardiotoxicity by regulating PPARα-dependent mitochondrial biogenesis
Akkermansia muciniphila ameliorates doxorubicin-induced cardiotoxicity by regulating PPARα-dependent mitochondrial biogenesis Open
Doxorubicin (DOX) is a key chemotherapeutic agent but is also a leading cause of DOX-induced cardiotoxicity (DIC), limiting its clinical use. Akkermansia muciniphila (A. muciniphila), known for its benefits as a probiotic in treating metab…
View article: Protective Role of H2S in High Glucose-Induced Cardiomyocyte and Endothelial Cell Dysfunction: A Mechanistic Review
Protective Role of H2S in High Glucose-Induced Cardiomyocyte and Endothelial Cell Dysfunction: A Mechanistic Review Open
Hydrogen sulfide (H2S), recognized as a significant gasotransmitter, has been shown to effectively reduce damage to cardiomyocytes and endothelial cells caused by diabetes. Its protective effects primarily stem from several mechanisms, inc…
View article: Construction and evaluation of a 180-day readmission prediction model for chronic heart failure patients based on sCD40L
Construction and evaluation of a 180-day readmission prediction model for chronic heart failure patients based on sCD40L Open
The high readmission rate of patients with chronic heart failure (HF) can cause waste of medical resources and economic losses. Establishing an effective HF readmission model can effectively alleviate medical pressure and improve the quali…
View article: Development of Vibrio parahaemolyticus sensitive and specific loop-mediated isothermal amplification combined with lateral flow device
Development of Vibrio parahaemolyticus sensitive and specific loop-mediated isothermal amplification combined with lateral flow device Open
The LAMP-LFD method for Vibrio parahaemolyticus established in this study has the advantages of convenient operation, low dependence on equipment, high sensitivity and rapid detection, all of make it ideally suited to the detection of Vibr…
View article: Indole‐3‐Lactic Acid Inhibits Doxorubicin‐Induced Ferroptosis Through Activating Aryl Hydrocarbon Receptor/Nrf2 Signalling Pathway
Indole‐3‐Lactic Acid Inhibits Doxorubicin‐Induced Ferroptosis Through Activating Aryl Hydrocarbon Receptor/Nrf2 Signalling Pathway Open
The clinical application of doxorubicin (DOX) is limited due to its cardiotoxicity, which is primarily attributed to its interaction with iron in mitochondria, leading to lipid peroxidation and myocardial ferroptosis. This study aimed to i…
View article: Immunomodulatory Effects of a Prebiotic Formula with 2′-Fucosyllactose and Galacto- and Fructo-Oligosaccharides on Cyclophosphamide (CTX)-Induced Immunosuppressed BALB/c Mice via the Gut–Immune Axis
Immunomodulatory Effects of a Prebiotic Formula with 2′-Fucosyllactose and Galacto- and Fructo-Oligosaccharides on Cyclophosphamide (CTX)-Induced Immunosuppressed BALB/c Mice via the Gut–Immune Axis Open
Obejectives: This study explored the immunomodulatory effects of a prebiotic formula consisting of 2′-fucosyllactose (2′-FL), galacto-oligosaccharides (GOSs), and fructo-oligosaccharides (FOSs) (hereinafter referred to as 2FGF) in cyclopho…
View article: LncRNA GHET1 from bone mesenchymal stem cell–derived exosomes improves doxorubicin-induced pyroptosis of cardiomyocytes by mediating NLRP3
LncRNA GHET1 from bone mesenchymal stem cell–derived exosomes improves doxorubicin-induced pyroptosis of cardiomyocytes by mediating NLRP3 Open
Doxorubicin (DOX) is an important chemotherapeutic agent for the treatment of hematologic tumors and breast carcinoma. However, its clinical application is limited owing to severe cardiotoxicity. Pyroptosis is a form of programmed cell dea…
View article: The association between smoking exposure and endothelial function evaluated using flow-mediated dilation values: a meta-analysis
The association between smoking exposure and endothelial function evaluated using flow-mediated dilation values: a meta-analysis Open
Background Tobacco use is recognized as a major cause of cardiovascular disease, which is associated with endothelial dysfunction. Endothelial function is evaluated using flow-mediated dilation (FMD), which is a noninvasive method. This me…
View article: Corrigendum: Influence of body composition assessment with bioelectrical impedance vector analysis in cancer patients undergoing surgery
Corrigendum: Influence of body composition assessment with bioelectrical impedance vector analysis in cancer patients undergoing surgery Open
[This corrects the article DOI: 10.3389/fonc.2023.1132972.].
View article: Impact of the gene polymorphisms in the renin-angiotensin system on cardiomyopathy risk: A meta-analysis
Impact of the gene polymorphisms in the renin-angiotensin system on cardiomyopathy risk: A meta-analysis Open
Due to the inconsistent findings from various studies, the role of gene polymorphisms in the renin-angiotensin system in influencing the development of cardiomyopathy remains unclear. In this study, we conducted a systematic review and met…
View article: The Role of Pyroptosis in Coronary Heart Disease
The Role of Pyroptosis in Coronary Heart Disease Open
The incidence and mortality of cardiovascular diseases, of which coronary heart disease (CHD) is a significant cardiovascular burden, are on the rise. Pyroptosis as an incipient programmed cell death mediated by inflammasomes can sense cyt…
View article: Perceptual Pattern of Cleft-Related Speech: A Task-fMRI Study on Typical Mandarin-Speaking Adults
Perceptual Pattern of Cleft-Related Speech: A Task-fMRI Study on Typical Mandarin-Speaking Adults Open
Congenital cleft lip and palate is one of the common deformities in the craniomaxillofacial region. The current study aimed to explore the perceptual pattern of cleft-related speech produced by Mandarin-speaking patients with repaired clef…
View article: Immune-Related Genes in the Pathogenesis of Atherosclerosis: Based on Sex Differences
Immune-Related Genes in the Pathogenesis of Atherosclerosis: Based on Sex Differences Open
This study demonstrates the effectiveness of seven IRGs and reveal sex differences in atherosclerosis. Notably, there is a significant presence of immune cells within the atherosclerotic plaque of men compared to women. These findings have…
View article: Influence of body composition assessment with bioelectrical impedance vector analysis in cancer patients undergoing surgery
Influence of body composition assessment with bioelectrical impedance vector analysis in cancer patients undergoing surgery Open
Background Malnutrition is common in patients undergoing surgery for cancers and is a risk factor for postoperative outcomes. Body composition provides information for precise nutrition intervention in perioperative period for improving pa…
View article: Construction and evaluation of a 180-day readmission prediction model for chronic heart failure patients based on sCD40L
Construction and evaluation of a 180-day readmission prediction model for chronic heart failure patients based on sCD40L Open
Background The high readmission rate of patients with chronic heart failure can cause waste of medical resources and economic losses. Establishing an effective heart failure readmission model can effectively alleviate medical pressure and …
View article: LncRNA GHET1 from bone mesenchymal stem cell–derived exosomes improves doxorubicin-induced pyroptosis of cardiomyocytes by mediating NLRP3
LncRNA GHET1 from bone mesenchymal stem cell–derived exosomes improves doxorubicin-induced pyroptosis of cardiomyocytes by mediating NLRP3 Open
Doxorubicin (DOX) is an important chemotherapeutic agent for the treatment of hematologic tumors and breast carcinoma. However, its clinical application is limited owing to severe cardiotoxicity. Pyroptosis is a form of programmed cell dea…
View article: [Hearing care network for early identification of delayed hearing loss in preschool children].
[Hearing care network for early identification of delayed hearing loss in preschool children]. Open
Objective:To establish a hearing care network for preschool children in Nanjing, to perform early identification and intervention for delayed hearing loss, and to evaluate the application effect of the hearing care network. Methods:Through…
View article: Role of Yellow Wine in Homocysteine-induced Endothelial Progenitor Cell Function
Role of Yellow Wine in Homocysteine-induced Endothelial Progenitor Cell Function Open
Background Increased Hcy level is an independent risk factor for coronary heart disease (CHD). It was proposed that yellow rice wine improves Hcy-induced EPCs dysfunction and inhibits the development of atherosclerotic plaques. In this stu…
View article: Acute Myocardial Infarction After Surgical Closure of Coronary Artery Fistula
Acute Myocardial Infarction After Surgical Closure of Coronary Artery Fistula Open
We present a case of a coronary arteriovenous fistula between the left circumflex (LCX) and the atrium with LCX ectasia. Four months after surgical closure of the fistula, the patient experienced acute myocardial infarction caused by throm…
View article: Low-Field NMR Experimental Study on the Effect of Confining Pressure on the Porous Structure and Connectivity of High-Rank Coal
Low-Field NMR Experimental Study on the Effect of Confining Pressure on the Porous Structure and Connectivity of High-Rank Coal Open
[Image: see text] To study the influence of different confining pressures on the pore structure and connectivity of high-rank coal, the high-rank raw coal of the Shanxi Xinjing Mine No. 9 coal seam was studied. A low-field nuclear magnetic…
View article: Takotsubo cardiomyopathy misdiagnosed as acute myocardial infarction under the Chest Pain Center model: A case report
Takotsubo cardiomyopathy misdiagnosed as acute myocardial infarction under the Chest Pain Center model: A case report Open
Under the Chest Pain Center model for the treatment of patients with chest pain showing ST segment elevation, despite the urgency of time, Takotsubo cardiomyopathy must be promptly differentiated from AMI for its appropriate management.
View article: METTL14 suppresses pyroptosis and diabetic cardiomyopathy by downregulating TINCR lncRNA
METTL14 suppresses pyroptosis and diabetic cardiomyopathy by downregulating TINCR lncRNA Open
N6-methyladenosine (m6A) is one of the most important epigenetic regulation of RNAs, such as lncRNAs. However, the underlying regulatory mechanism of m6A in diabetic cardiomyopathy (DCM) is very limited. In this study, we sought to define …
View article: Crotalaria ferruginea extract attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting MAPK/NF-κB signaling pathways
Crotalaria ferruginea extract attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting MAPK/NF-κB signaling pathways Open
Objective: To evaluate the anti-inflammatory activity of Crotalaria ferruginea extract (CFE) and its mechanism. Methods: An intratracheal lipopolysaccharide (LPS) instillation-induced acute lung injury (ALI) model was used to study the ant…
View article: Yellow Wine Polyphenolic Compound Protects Against Doxorubicin-Induced Cardiotoxicity by Modulating the Composition and Metabolic Function of the Gut Microbiota
Yellow Wine Polyphenolic Compound Protects Against Doxorubicin-Induced Cardiotoxicity by Modulating the Composition and Metabolic Function of the Gut Microbiota Open
Background: Dietary polyphenols help to prevent cardiovascular diseases, and interactions between polyphenols and gut microbiota are known to exist. In this study, we speculated that gut microbiota-mediated metabolite regulation might cont…
View article: METTL14 Suppresses Pyroptosis and Diabetic Cardiomyopathy by Down-Regulating TINCR lncRNA
METTL14 Suppresses Pyroptosis and Diabetic Cardiomyopathy by Down-Regulating TINCR lncRNA Open
Background: N6-methyladenosine (m6A) is one of the most important epigenetic regulation of RNAs, such as lncRNAs. However, the underlying regulatory mechanism of m6A in diabetic cardiomyopathy (DCM) is very limited. In this study, we sough…