Liqin Liu
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View article: The Hopf Bifurcation Analysis of the Boissonade Model with Time Delay and Diffusion
The Hopf Bifurcation Analysis of the Boissonade Model with Time Delay and Diffusion Open
This paper investigates the dynamical characteristics of the Boissonade model in a class of reaction–diffusion chemical systems with time delays, analyzing the system’s Hopf bifurcation with time delay as the parameter under both diffusion…
View article: An engineered VSV-vectored rabies vaccine with an RABV-G-L71S mutation
An engineered VSV-vectored rabies vaccine with an RABV-G-L71S mutation Open
A replicating recombinant rabies vaccine, rVSV-RABV, was constructed using vesicular stomatitis virus (VSV) expressing the rabies virus glycoprotein (RABV-G, SAD-B19 strain). A leucine-to-serine mutation at position 71 (L71S) in the RABV-G…
View article: Estimating Major Pathological Response in Non-Small Cell Lung Cancer Patients with post-Neoadjuvant Therapy Using MMT-Net
Estimating Major Pathological Response in Non-Small Cell Lung Cancer Patients with post-Neoadjuvant Therapy Using MMT-Net Open
Neoadjuvant therapy (NAT) has demonstrated considerable effectiveness in treating locally advanced non-small cell lung cancer (NSCLC). Major pathological response (MPR), defined by the proportion of viable tumor cells in the tumor bed asse…
View article: Exploration of the GRAS family in Dimocarpus longan: identification, characterization, expression analysis and DlGRAS24 role in flowering time
Exploration of the GRAS family in Dimocarpus longan: identification, characterization, expression analysis and DlGRAS24 role in flowering time Open
View article: Construction and Practice of Digital Twin Operation and Maintenance Platform for Water Supply and Drainage Systems in New Energy Power Stations
Construction and Practice of Digital Twin Operation and Maintenance Platform for Water Supply and Drainage Systems in New Energy Power Stations Open
To address the critical challenges of low operational reliability, high energy consumption, and inefficient fault response in water supply and drainage (WSD) systems of new energy power stations (NEPS), this study proposes a digital twin (…
View article: A Quad-Channel Diplexer Using Stub-Loaded Step Impedance Resonators
A Quad-Channel Diplexer Using Stub-Loaded Step Impedance Resonators Open
A quad-channel diplexer is designed in this paper. The diplexer is composed of four stub-loaded step impedance resonators and a common feeder T-joint, which realizes four passbands with center frequencies of 2.6 GHz, 3.48 GHz, 4.8 GHz, and…
View article: Synergistic effects of feedback regulation and vegetation internal competition on vegetation patterns in semi-arid environments
Synergistic effects of feedback regulation and vegetation internal competition on vegetation patterns in semi-arid environments Open
View article: Antibodies elicited by hepatitis E vaccination in humans confer cross-genus protection against rat hepatitis E virus
Antibodies elicited by hepatitis E vaccination in humans confer cross-genus protection against rat hepatitis E virus Open
View article: Neural mechanisms underlying cognitive changes in individuals with alcohol use disorder: insights from resting-state functional magnetic resonance imaging
Neural mechanisms underlying cognitive changes in individuals with alcohol use disorder: insights from resting-state functional magnetic resonance imaging Open
The AUD patients demonstrated significant resting-state functional alterations across multiple brain regions, and dysregulation in the right inferior frontal gyrus emerged as a potential neural substrate for their cognitive deficits.
View article: Differential phytohormone related senescence regulation in main and lateral roots of longan (Dimocarpus longan Lour.)
Differential phytohormone related senescence regulation in main and lateral roots of longan (Dimocarpus longan Lour.) Open
View article: Genome-wide identification and functional analysis of the longan CONSTANS (CO) family
Genome-wide identification and functional analysis of the longan CONSTANS (CO) family Open
Longans are among the most economically important subtropical fruits. Its flowering is sensitive to the photoperiod, and flowering time has a significant influence on yield and quality. CONSTANS-like (COL) gene plays a key role in regulati…
View article: Transparency of clinical practice guidelines: A mixed methods research
Transparency of clinical practice guidelines: A mixed methods research Open
View article: Comparison of muscle structure and transcriptome analysis of eyed-side muscle and blind-side muscle in Cynoglossus semilaevis (Osteichthyes, Cynoglossidae)
Comparison of muscle structure and transcriptome analysis of eyed-side muscle and blind-side muscle in Cynoglossus semilaevis (Osteichthyes, Cynoglossidae) Open
Cynoglossus semilaevis (Osteichthyes, Cynoglossidae) is one of the most significant commercial marine fish species in China and has evolved a specialized asymmetrical body axis. In addition, C. semilaevis displays different muscle thicknes…
View article: Using RAD-seq to identify and differentiate the medicinal herb Scrophularia ningpoensis and its adulterants
Using RAD-seq to identify and differentiate the medicinal herb Scrophularia ningpoensis and its adulterants Open
This study successfully identified S. ningpoensis and the three adulterants, enriched the genomic information of Scrophularia species, and contributed to a more profound understanding of the evolutionary dynamics within this genus. Further…
View article: A single residue switch mediates the broad neutralization of Rotaviruses
A single residue switch mediates the broad neutralization of Rotaviruses Open
Broadly neutralizing antibodies (bNAbs) could offer escape-tolerant and lasting protection against viral infections and therefore guide development of broad-spectrum vaccines. The increasing challenge posed by viral evolution and immune ev…
View article: Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy
Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy Open
Objective Approximately 7% of individuals with dystrophinopathy remain undiagnosed at the genetic level using conventional genetic tests like multiplex ligation‐dependent probe amplification (MLPA) and next‐generation sequencing (NGS). We …
View article: A potent broad-spectrum neutralizing antibody targeting a conserved region of the prefusion RSV F protein
A potent broad-spectrum neutralizing antibody targeting a conserved region of the prefusion RSV F protein Open
View article: The Fluorescent Sensing of BF3 and Amines: A Dual Approach with Hydrazone Ligands
The Fluorescent Sensing of BF3 and Amines: A Dual Approach with Hydrazone Ligands Open
BF3, volatile amines (VOAs), and biogenic amines (BAs) are the key indicators in chemical reaction catalysis and food quality monitoring. In this study, we present two types of fluorescent sensors, a hydrazone ligand (HL)-based fluorescent…
View article: Sintilimab plus HPV vaccine for recurrent or metastatic cervical cancer
Sintilimab plus HPV vaccine for recurrent or metastatic cervical cancer Open
Purpose Recurrent or metastatic cervical cancer (r/m CC) presents limited treatment options for patients failed or progressed quickly following first-line therapy. This study investigated the potential of sintilimab with a prophylactic hum…
View article: Research on the Effect of a Heave Plate on the Dynamics of the Floating Wind Turbine Using Model Tests
Research on the Effect of a Heave Plate on the Dynamics of the Floating Wind Turbine Using Model Tests Open
The increasing demand to harness offshore wind resources has pushed offshore wind turbines into deeper waters, making floating platforms more economically feasible than bottom-fixed ones. When the incident wind and wave forces act on the f…
View article: Harnessing natural inhibitors of protein synthesis for cancer therapy: A comprehensive review
Harnessing natural inhibitors of protein synthesis for cancer therapy: A comprehensive review Open
Cancer treatment remains a formidable challenge in modern medicine, necessitating a nuanced understanding of its molecular underpinnings and the identification of novel therapeutic modalities. Among the intricate web of cellular pathways i…
View article: Differential phytohormone related senescence regulation in main and lateral roots of longan (Dimocarpus longan Lour.)
Differential phytohormone related senescence regulation in main and lateral roots of longan (Dimocarpus longan Lour.) Open
Root senescence (RS) is a common phenomenon in longan, however, the regulation of RS is poorly understood. In this study, the main root was divided into three segments from tip to crown, i.e., distal (MDR), middle (MMR) and proximal (MPR) …
View article: Glycoprotein E-Displaying Nanoparticles Induce Robust Neutralizing Antibodies and T-Cell Response against Varicella Zoster Virus
Glycoprotein E-Displaying Nanoparticles Induce Robust Neutralizing Antibodies and T-Cell Response against Varicella Zoster Virus Open
The Varicella zoster virus (VZV), responsible for both varicella (chickenpox) and herpes zoster (shingles), presents significant global health challenges. While primary VZV infection primarily affects children, leading to chickenpox, react…
View article: Investigation of TSRP reverses imatinib resistance through the PI3K / Akt pathway in chronic myeloid leukemia
Investigation of TSRP reverses imatinib resistance through the PI3K / Akt pathway in chronic myeloid leukemia Open
Chronic myelogenous leukemia (CML) is a malignant tumor of the blood system, so far there is no effective cure. Imatinib (IM), as the first-line drug for the clinical targeted treatment of CML, has some limiting factors such as drug resist…
View article: Expression and diagnostic value of serum free light chain in lung cancer.
Expression and diagnostic value of serum free light chain in lung cancer. Open
Serum FLC is highly expressed in lung cancer and is associated with its invasion and metastasis. Serum FLC, particularly κFLC, has diagnostic value for lung cancer, and the combined detection of FLC, CEA, and CYFRA21-1 offers the best diag…
View article: Population structure of Taenioides sp. (Gobiiformes, Gobiidae) reveals their invasion history to inland waters of China based on mitochondrial DNA control region
Population structure of Taenioides sp. (Gobiiformes, Gobiidae) reveals their invasion history to inland waters of China based on mitochondrial DNA control region Open
Taenioides sp. is a small temperate fish originally known to inhabit muddy bottoms of brackish waters in coastal areas of China. However, it began to invade multiple inland freshwaters and caused severe damage to Chinese aquatic ecosystems…
View article: MetaEarth: A Generative Foundation Model for Global-Scale Remote Sensing Image Generation
MetaEarth: A Generative Foundation Model for Global-Scale Remote Sensing Image Generation Open
The recent advancement of generative foundational models has ushered in a new era of image generation in the realm of natural images, revolutionizing art design, entertainment, environment simulation, and beyond. Despite producing high-qua…
View article: Research on Dual-Grating Spacing Calibration Method Based on Multiple Improved Complete Ensemble Empirical Mode Decomposition with Adaptive Noise Combined with Hilbert Transform
Research on Dual-Grating Spacing Calibration Method Based on Multiple Improved Complete Ensemble Empirical Mode Decomposition with Adaptive Noise Combined with Hilbert Transform Open
The paper proposes a method for the calibration of spacing in dual-grating based on Multiple Improved Complete Ensemble Empirical Mode Decomposition with Adaptive Noise (ICEEMDAN) combined with Hilbert Transform (HT), referred to as Multip…
View article: A neutralizing antibody potently prevents RSV A and B infections by targeting a conserved region of the prefusion F
A neutralizing antibody potently prevents RSV A and B infections by targeting a conserved region of the prefusion F Open
Respiratory syncytial virus (RSV) poses a significant public health challenge, especially among children. Although palivizumab and nirsevimab, neutralizing antibodies (nAbs) targeting the RSV F protein, have been used for prophylaxis, thei…
View article: In vitro and in vivo experimental investigation Of TSRP reverses imatinib resistance through the PI3K / Akt pathway in chronic myeloid leukemia
In vitro and in vivo experimental investigation Of TSRP reverses imatinib resistance through the PI3K / Akt pathway in chronic myeloid leukemia Open
Chronic myelogenous leukemia (CML) is a malignant tumor of the blood system, so far there is no effective cure. Imatinib (IM), as the first-line drug for the clinical targeted treatment of CML, has some limiting factors such as drug resist…