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Label‐Free Multiphoton Microscopy for Diagnosis of Psoriasis Open

Liqin Zheng, L.H. Wu, Wenwen Zhong, Shengrong Du, Zhen Li , et al. · 2025

Psoriasis is a global problem that significantly affects patients both physically and mentally. Accurate and rapid detection of psoriasis is crucial for diagnosis and treatment. Herein, we utilized multiphoton microscopy (MPM) to rapidly i…

The Relationship Between Composite Inflammatory Ratios and Complications of Massive Ischaemic Stroke Open

Liqin Zheng, Zhijian Lin · 2024

Massive cerebral infarction, Neutrophil-to-lymphocyte ratio, Systemic immune inflammation index, Prognosis.

Prognostic value of tumor necrosis based on the evaluation of frequency in invasive breast cancer Open

Jianhua Chen, Zhijun Li, Zhonghua Han, Deyong Kang, Jianli Ma , et al. · 2023

Background Tumor necrosis (TN) was associated with poor prognosis. However, the traditional classification of TN ignored spatial intratumor heterogeneity, which may be associated with important prognosis. The purpose of this study was to p…

Supplemental Figure Legends from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure Legends

Supplemental Figure 3 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 3: Etomoxir decreases CPT-1 enzymatic activity in vivo, decreases Treg accumulation in spleens.

Supplemental Figure 5 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 5: FAO inhibitors do not affect the activation and function of T cells.

Supplemental Figure 3 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 3: Etomoxir decreases CPT-1 enzymatic activity in vivo, decreases Treg accumulation in spleens.

Supplemental Figure 4 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 4: FAO inhibitors do not affect the growth of tumor cells, cancer stem cells (spheres) or the expression of cancer stem-cell markers.

Supplemenatl Figure 6 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 6. The combined use of Etomoxir and CTX in vivo inhibits all immunosuppressive activity in T-MDSCs.

Supplemental Figure Legends from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure Legends

Supplemental Figure 5 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 5: FAO inhibitors do not affect the activation and function of T cells.

Supplemental Figure 1 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 1: FAO is increased in immunosuppressive T-MDSCs.

Supplemental Figure 2 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 2: Etomoxir lowers CPT1 enzymatic activity but does not alter the generation of MDSC subsets, induce apoptosis, or affect proliferation in BM-MDSCs.

Data from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Myeloid-derived suppressor cells (MDSC) promote tumor growth by inhibiting T-cell immunity and promoting malignant cell proliferation and migration. The therapeutic potential of blocking MDSC in tumors has been limited by their heterogenei…

Supplemental Figure 2 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 2: Etomoxir lowers CPT1 enzymatic activity but does not alter the generation of MDSC subsets, induce apoptosis, or affect proliferation in BM-MDSCs.

Data from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Myeloid-derived suppressor cells (MDSC) promote tumor growth by inhibiting T-cell immunity and promoting malignant cell proliferation and migration. The therapeutic potential of blocking MDSC in tumors has been limited by their heterogenei…

Supplemental Figure 1 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 1: FAO is increased in immunosuppressive T-MDSCs.

Supplemental Figure 4 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 4: FAO inhibitors do not affect the growth of tumor cells, cancer stem cells (spheres) or the expression of cancer stem-cell markers.

Supplemenatl Figure 6 from Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies Open

Fokhrul Hossain, Amir A. Al-Khami, Dorota Wyczechowska, Claudia Hernández, Liqin Zheng , et al. · 2023

Supplemental Figure 6. The combined use of Etomoxir and CTX in vivo inhibits all immunosuppressive activity in T-MDSCs.

Data from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4 Open

Ratika Srivastava, Degui Geng, Yingjia Liu, Liqin Zheng, Zhaoyang Li , et al. · 2023

Toll-like receptors (TLR) are expressed by a variety of cancers, including melanoma, but their functional contributions in cancer cells are uncertain. To approach this question, we evaluated the effects of stimulating or inhibiting the TLR…

Supplementary Figure 3 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4 Open

Ratika Srivastava, Degui Geng, Yingjia Liu, Liqin Zheng, Zhaoyang Li , et al. · 2023

PDF file - 49K, Role of TLR-induced cytokines and NF-kB on cell survival

Supplementary Figure 5 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4 Open

Ratika Srivastava, Degui Geng, Yingjia Liu, Liqin Zheng, Zhaoyang Li , et al. · 2023

PDF file - 144K, Effects of TLR stimulation and cytokines on IRAK phosphorylation in melanoma cells

Supplementary Figure 4 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4 Open

Ratika Srivastava, Degui Geng, Yingjia Liu, Liqin Zheng, Zhaoyang Li , et al. · 2023

PDF file - 66K, Apoptosis-related gene transcription array of A375 melanoma cells following IRAK inhibition with or without vinblastine

Supplementary Figure 4 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4 Open

Ratika Srivastava, Degui Geng, Yingjia Liu, Liqin Zheng, Zhaoyang Li , et al. · 2023

PDF file - 66K, Apoptosis-related gene transcription array of A375 melanoma cells following IRAK inhibition with or without vinblastine

Supplementary Figures 1-3 from Amplifying TLR-MyD88 Signals within Tumor-Specific T Cells Enhances Antitumor Activity to Suboptimal Levels of Weakly Immunogenic Tumor Antigens Open

Degui Geng, Liqin Zheng, Ratika Srivastava, Cruz Velasco‐Gonzalez, Adam I. Riker , et al. · 2023

Supplementary Figures 1-3 from Amplifying TLR-MyD88 Signals within Tumor-Specific T Cells Enhances Antitumor Activity to Suboptimal Levels of Weakly Immunogenic Tumor Antigens

Supplementary Figure 2 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4 Open

Ratika Srivastava, Degui Geng, Yingjia Liu, Liqin Zheng, Zhaoyang Li , et al. · 2023

PDF file - 48K, Inhibiting IRAK-1/-4 abrogates the effects of TLR1-TLR2 agonist in melanoma cells

Data from Amplifying TLR-MyD88 Signals within Tumor-Specific T Cells Enhances Antitumor Activity to Suboptimal Levels of Weakly Immunogenic Tumor Antigens Open

Degui Geng, Liqin Zheng, Ratika Srivastava, Cruz Velasco‐Gonzalez, Adam I. Riker , et al. · 2023

The efficacy of T cell–based immunotherapy to treat cancer patients remains a challenge partly because of the weak activity toward subdominant tumor antigens (TAg) and to tumors expressing suboptimal TAg levels. Recent reports indicate tha…

Supplementary Figure 1 from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4 Open

Ratika Srivastava, Degui Geng, Yingjia Liu, Liqin Zheng, Zhaoyang Li , et al. · 2023

PDF file - 77K, Overexpressing IRAK-1 in melanoma cells augments the expression of various cytokines and chemokines

Data from Augmentation of Therapeutic Responses in Melanoma by Inhibition of IRAK-1,-4 Open

Ratika Srivastava, Degui Geng, Yingjia Liu, Liqin Zheng, Zhaoyang Li , et al. · 2023

Toll-like receptors (TLR) are expressed by a variety of cancers, including melanoma, but their functional contributions in cancer cells are uncertain. To approach this question, we evaluated the effects of stimulating or inhibiting the TLR…

Supplementary Figures 1-3 from Amplifying TLR-MyD88 Signals within Tumor-Specific T Cells Enhances Antitumor Activity to Suboptimal Levels of Weakly Immunogenic Tumor Antigens Open

Degui Geng, Liqin Zheng, Ratika Srivastava, Cruz Velasco‐Gonzalez, Adam I. Riker , et al. · 2023

Supplementary Figures 1-3 from Amplifying TLR-MyD88 Signals within Tumor-Specific T Cells Enhances Antitumor Activity to Suboptimal Levels of Weakly Immunogenic Tumor Antigens

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