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View article: Drying Temperature Dictates Ileal Amino Acid Digestibility of Enzyme-Treated Soybean Meal in 25 kg Pigs
Drying Temperature Dictates Ileal Amino Acid Digestibility of Enzyme-Treated Soybean Meal in 25 kg Pigs Open
Soybean meal causes health issues in piglets due to the presence of antigenic proteins. Although enzymatic treatment can break down antigenic proteins, subsequent high-temperature drying may impair amino acid (AA) digestibility via the Mai…
View article: 2-Month Outcomes of Conbercept in Macular Edema Secondary to Central Retinal Vein Occlusion from a randomized, multicenter, double-blind, sham-controlled phase III study: CRAVE Study
2-Month Outcomes of Conbercept in Macular Edema Secondary to Central Retinal Vein Occlusion from a randomized, multicenter, double-blind, sham-controlled phase III study: CRAVE Study Open
Purpose To evaluate the efficacy and safety of intravitreal injection of conbercept for the treatment of macular edema secondary to central retinal vein occlusion (CRVO-ME). Methods Patients with CRVO were randomly divided into the treatme…
View article: Calcium, non-phytate phosphorus and electrolyte balance in low-protein diet influence growth, tibia development and muscular protein deposition in medium-growing yellow-feathered broilers
Calcium, non-phytate phosphorus and electrolyte balance in low-protein diet influence growth, tibia development and muscular protein deposition in medium-growing yellow-feathered broilers Open
Excessive protein intake increases production costs and pollutant emissions in poultry production. As a result, low-protein diets supplemented with essential amino acids is considered a new normal. However, the mineral requirements in low-…
View article: Decoding the interaction mechanism between pectin and oral mucin to enhance saltiness
Decoding the interaction mechanism between pectin and oral mucin to enhance saltiness Open
View article: Cadmium-associated molecular pathways drive gender-specific pathogenesis and prognosis in lung adenocarcinoma
Cadmium-associated molecular pathways drive gender-specific pathogenesis and prognosis in lung adenocarcinoma Open
Lung adenocarcinoma (LUAD) demonstrates pronounced female predominance and escalating incidence, yet sex-specific environmental determinants remain poorly characterized. This study elucidates cadmium (Cd)-associated molecular mechanisms dr…
View article: DAZAP1 maintains gastric cancer stemness by inducing mitophagy
DAZAP1 maintains gastric cancer stemness by inducing mitophagy Open
Stem cells play a pivotal role in the malignant behavior of gastric cancer (GC), complicating its treatment and prognosis. However, the regulatory mechanisms of GC stem cells (GCSCs) remain poorly understood. DAZ-associated protein 1 (DAZA…
View article: Effect of inhibition of reactivated alcohol-associated memories with propranolol on alcohol craving
Effect of inhibition of reactivated alcohol-associated memories with propranolol on alcohol craving Open
The protocol was registered at www.chictr.org.cn on October 13, 2023 (Chinese Clinical Trial Registry, identification number ChiCTR2300076633, Retrospectively registered).
View article: Clinical risk score to predict poor coronary collateralization in type 2 diabetic patients with chronic total occlusion
Clinical risk score to predict poor coronary collateralization in type 2 diabetic patients with chronic total occlusion Open
View article: Association of thromboxane generation with the bleeding events in aspirin users
Association of thromboxane generation with the bleeding events in aspirin users Open
Coronary artery disease is among the leading causes of morbidity and mortality worldwide, posing a significant threat to human health and life. Aspirin is widely used in the treatment of coronary artery disease, however, long-term use may …
View article: Analyze the Diversity and Function of Immune Cells in the Tumor Microenvironment From the Perspective of Single‐Cell <scp>RNA</scp> Sequencing
Analyze the Diversity and Function of Immune Cells in the Tumor Microenvironment From the Perspective of Single‐Cell <span>RNA</span> Sequencing Open
Background Cancer development is closely associated with complex alterations in the tumor microenvironment (TME). Among these, immune cells within the TME play a huge role in personalized tumor diagnosis and treatment. Objectives This revi…
View article: Relative bioavailability of selenium yeast, selenomethionine, hydroxyl-selenomethionine and nano-selenium for broilers
Relative bioavailability of selenium yeast, selenomethionine, hydroxyl-selenomethionine and nano-selenium for broilers Open
Selenium (Se) is an essential trace element for humans and animals. Development and application of new forms of Se sources with lower toxicity and higher bioavailability has been attracting more attention. However, the bioavailabilities of…
View article: Low protein diet influences mineral absorption and utilization in medium-growing yellow-feathered broilers from 1 to 30 days of age
Low protein diet influences mineral absorption and utilization in medium-growing yellow-feathered broilers from 1 to 30 days of age Open
Reduced-protein diet can save protein ingredients and reduce nitrogen (N) losses. However, the effect of low protein diet on the mineral uptake and utilization in broilers needs to be explored. The aim of this study was to investigate the …
View article: <scp>METTL14</scp> attenuates cancer stemness by suppressing <scp>ATF5</scp>/<scp>WDR74</scp>/β‐catenin axis in gastric cancer
<span>METTL14</span> attenuates cancer stemness by suppressing <span>ATF5</span>/<span>WDR74</span>/β‐catenin axis in gastric cancer Open
Stemness is a key factor contributing to treatment failure in gastric cancer (GC). Methyltransferase‐like 14 (METTL14) has been linked to various cancers, though its specific role in regulating stemness in GC remains undefined. In this stu…
View article: Clusterin from endometrial glands plays a critical role in decidualization via Trem2
Clusterin from endometrial glands plays a critical role in decidualization via Trem2 Open
View article: A novel long non-coding RNA WASIR2 regulates MEX3A expression by sponging miR-374b-5p and promotes lung adenocarcinoma progression
A novel long non-coding RNA WASIR2 regulates MEX3A expression by sponging miR-374b-5p and promotes lung adenocarcinoma progression Open
Background Long noncoding RNAs (lncRNAs) have been reported to play important roles in the progression of lung adenocarcinoma (LUAD). However, the expressions and function of lncRNA WASIR2 remain largely unknown in LUAD. Methods Differenti…
View article: METTL14 attenuates cancer stemness by suppressing ATF5/WDR74/β-catenin axis in gastric cancer
METTL14 attenuates cancer stemness by suppressing ATF5/WDR74/β-catenin axis in gastric cancer Open
Purpose Stemness is one of the leading causes of treatment failure in gastric cancer (GC). Methyltransferase-like 14 (METTL14) participates in several malignancies. But the precise mechanisms of METTL14 in regulating GC stemness are still …
View article: Zinc alleviates thermal stress-induced damage to the integrity and barrier function of cultured chicken embryonic primary jejunal epithelial cells via the MAPK and PI3K/AKT/mTOR signaling pathways
Zinc alleviates thermal stress-induced damage to the integrity and barrier function of cultured chicken embryonic primary jejunal epithelial cells via the MAPK and PI3K/AKT/mTOR signaling pathways Open
View article: Risk Factors for Non-Suicidal Self-Injury in Children and Adolescents: An Umbrella Review
Risk Factors for Non-Suicidal Self-Injury in Children and Adolescents: An Umbrella Review Open
View article: Effects of Age and Rapeseed Meal Source on Apparent and Standardized Ileal Amino Acid Digestibility of Broilers
Effects of Age and Rapeseed Meal Source on Apparent and Standardized Ileal Amino Acid Digestibility of Broilers Open
View article: Dietary calcium and nonphosphate phosphorus interaction influences tibiotarsus development and related gene expression of broilers from 1 to 21 days of age
Dietary calcium and nonphosphate phosphorus interaction influences tibiotarsus development and related gene expression of broilers from 1 to 21 days of age Open
View article: Management Strategies for Acute Type A Aortic Dissection Complicated By Limb Malperfusion
Management Strategies for Acute Type A Aortic Dissection Complicated By Limb Malperfusion Open
Background: Acute type A aortic dissection complicated by limb malperfusion presents a risk of mortality to the patients. Debates exist regarding management, whether focused on reperfusion first or immediate repair. Here, we aimed to descr…
View article: Postoperative Myocardial Infarction in Acute Type A Aortic Dissection: A Case Report
Postoperative Myocardial Infarction in Acute Type A Aortic Dissection: A Case Report Open
Postoperative myocardial infarction (POMI) in acute type A aortic dissection rarely has been reported, we report a case of postoperative myocardial infarction in acute type A aortic dissection, and the clinical presentation and possible me…
View article: Dietary trace mineral pattern influences gut microbiota and intestinal health of broilers
Dietary trace mineral pattern influences gut microbiota and intestinal health of broilers Open
Dietary trace minerals can impact gut flora, which can further affect intestinal health. However, the dietary balance pattern of trace minerals for the intestinal health of broilers needs to be explored. The present study was conducted to …
View article: Expression and Regulation of a Novel Decidual Cells-Derived Estrogen Target during Decidualization
Expression and Regulation of a Novel Decidual Cells-Derived Estrogen Target during Decidualization Open
During decidualization in rodents, uterine stromal cells undergo extensive reprogramming to differentiate into distinct cell types, forming primary decidual zones (PDZs), secondary decidual zones (SDZs), and layers of undifferentiated stro…
View article: Effect of Blood Hemoperfusion Therapy in Acute Type A Aortic Dissection Surgery：a retrospective observational study
Effect of Blood Hemoperfusion Therapy in Acute Type A Aortic Dissection Surgery：a retrospective observational study Open
Background Although hemoperfusion is considered an efficient technique of removal specific solutes in inflammatory states, there is no established indications for triggered treatment. This study aimed to evaluate whether the adding of a ne…
View article: Establishment and evaluation of the primary cultured tibial osteoblast model of broiler chicks
Establishment and evaluation of the primary cultured tibial osteoblast model of broiler chicks Open
Osteoblasts are considered as a major factor contributing to bone development and mineralization, however, few studies have been done to establish and evaluate the primary cultured tibial osteoblast model of broiler chicks. Therefore, in t…
View article: Management strategies for acute type A aortic dissection complicated by limb malperfusion
Management strategies for acute type A aortic dissection complicated by limb malperfusion Open
Objective : Acute type A aortic dissection complicated by limb malperfusion confers a risk of mortality to the patients. And,debates still exist about how to manage the predicament focused on reperfusion first or immediate repair.Here,we a…
View article: CHCHD2 maintains mitochondrial contact site and cristae organizing system stability and protects against mitochondrial dysfunction in an experimental model of Parkinson's disease
CHCHD2 maintains mitochondrial contact site and cristae organizing system stability and protects against mitochondrial dysfunction in an experimental model of Parkinson's disease Open
Background: Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's dementia. Mitochondrial dysfunction is involved in the pathology of PD. Coiled-coil-helix-coiled-coil-helix domain-containing 2 (CHC…
View article: Effect of the gene silencing of phosphorus transporters on phosphorus absorption across primary cultured duodenal epithelial cell monolayers of chick embryos
Effect of the gene silencing of phosphorus transporters on phosphorus absorption across primary cultured duodenal epithelial cell monolayers of chick embryos Open
The aim of the study was to investigate whether phosphorus (P) transporters, type IIb sodium-dependent phosphate cotransporter (NaP-IIb) and inorganic phosphate transporter 2 (PiT2), were directly involved in P absorption across primary cu…
View article: Effect of in ovo manganese injection on the embryonic development, antioxidation, hatchability, and performances of offspring broilers under normal and high temperatures
Effect of in ovo manganese injection on the embryonic development, antioxidation, hatchability, and performances of offspring broilers under normal and high temperatures Open