Liran Mao
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View article: Spatial profiling of chromatin accessibility in formalin-fixed paraffin-embedded tissues
Spatial profiling of chromatin accessibility in formalin-fixed paraffin-embedded tissues Open
Formalin-fixed paraffin-embedded (FFPE) samples represent a vast, untapped resource for epigenomic research, yet molecular tools for deep analysis of these specimens remain limited. We introduce spatial FFPE-ATAC-seq, an approach for in si…
View article: Multiplexed spatial mapping of chromatin features, transcriptome, and proteins in tissues
Multiplexed spatial mapping of chromatin features, transcriptome, and proteins in tissues Open
The phenotypic and functional states of a cell are modulated by a complex interactive molecular hierarchy of multiple omics layers, involving the genome, epigenome, transcriptome, proteome, and metabolome. Spatial omics approaches have ena…