Liran Yadgary
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View article: Large changes in detected selection signatures after a selection limit in mice bred for voluntary wheel-running behavior
Large changes in detected selection signatures after a selection limit in mice bred for voluntary wheel-running behavior Open
In various organisms, sequencing of selectively bred lines at apparent selection limits has demonstrated that genetic variation can remain at many loci, implying that evolution at the genetic level may continue even if the population mean …
View article: Large changes in detected selection signatures after a selection limit in mice bred for voluntary wheel-running behavior
Large changes in detected selection signatures after a selection limit in mice bred for voluntary wheel-running behavior Open
In various organisms, sequencing of selectively bred lines at apparent selection limits has demonstrated that genetic variation can remain at many loci, implying that evolution at the genetic level may continue even if the population mean …
View article: A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2
A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2 Open
Significant departures from expected Mendelian inheritance ratios (transmission ratio distortion, TRD) are frequently observed in both experimental crosses and natural populations. TRD on mouse Chromosome (Chr) 2 has been reported in multi…
View article: Genetic Basis of Aerobically Supported Voluntary Exercise: Results from a Selection Experiment with House Mice
Genetic Basis of Aerobically Supported Voluntary Exercise: Results from a Selection Experiment with House Mice Open
House mice from 4 replicate lines selectively bred for 61 generations for voluntary wheel-running behavior were compared with 4 non-selected control lines using multiple genome-wide analytical techniques on both haplotype and single nucleo…
View article: The Evolutionary Fates of a Large Segmental Duplication in Mouse
The Evolutionary Fates of a Large Segmental Duplication in Mouse Open
Gene duplication and loss are major sources of genetic polymorphism in populations, and are important forces shaping the evolution of genome content and organization. We have reconstructed the origin and history of a 127-kbp segmental dupl…
View article: The Evolutionary Fates of a Large Segmental Duplication in Mouse
The Evolutionary Fates of a Large Segmental Duplication in Mouse Open
Gene duplication and loss are major sources of genetic polymorphism in populations, and are important forces shaping the evolution of genome content and organization. We have reconstructed the origin and history of a 127-kbp segmental dupl…
View article: The evolutionary fates of a large segmental duplication in mouse
The evolutionary fates of a large segmental duplication in mouse Open
Gene duplication and loss are major sources of genetic polymorphism in populations, and are important forces shaping the evolution of genome content and organization. We have reconstructed the origin and history of a 127 kbp segmental dupl…
View article: <i>R2d2</i> Drives Selfish Sweeps in the House Mouse
<i>R2d2</i> Drives Selfish Sweeps in the House Mouse Open
A selective sweep is the result of strong positive selection driving newly occurring or standing genetic variants to fixation, and can dramatically alter the pattern and distribution of allelic diversity in a population. Population-level s…