Lisa Caboor
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View article: Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture
Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture Open
Thoracic aortic aneurysm and dissection (TAAD) associates with a high mortality rate. Despite the existence of different mouse models for TAAD, the underlying disease mechanisms remain elusive. Treatment options are limited and mainly cons…
View article: From Corrosion Casting to Virtual Dissection: Contrast‐Enhanced Vascular Imaging using Hafnium Oxide Nanocrystals
From Corrosion Casting to Virtual Dissection: Contrast‐Enhanced Vascular Imaging using Hafnium Oxide Nanocrystals Open
Vascular corrosion casting is a method used to visualize the three dimensional (3D) anatomy and branching pattern of blood vessels. A polymer resin is injected in the vascular system and, after curing, the surrounding tissue is removed. Th…
View article: Application of an automated analysis framework for pulsed-wave Doppler cardiac ultrasound measurements to generate reference data in adult zebrafish
Application of an automated analysis framework for pulsed-wave Doppler cardiac ultrasound measurements to generate reference data in adult zebrafish Open
High-frequency cardiac ultrasound is the only well-established method to characterize in vivo cardiovascular function in adult zebrafish noninvasively. Pulsed-wave Doppler imaging allows measurements of blood flow velocities at well-define…
View article: From corrosion casting to virtual dissection: contrast-enhanced vascular imaging using hafnium oxide nanocrystals
From corrosion casting to virtual dissection: contrast-enhanced vascular imaging using hafnium oxide nanocrystals Open
Vascular corrosion casting is a method used to visualize the three dimensional anatomy and branching pattern of blood vessels, guiding insight into health and cardiovascular disease pathogenesis and progression. A polymer resin is injected…
View article: Fluid-Structure Interaction Modeling of the Aortic Hemodynamics in Adult Zebrafish: A Pilot Study Based on Synchrotron X-Ray Tomography
Fluid-Structure Interaction Modeling of the Aortic Hemodynamics in Adult Zebrafish: A Pilot Study Based on Synchrotron X-Ray Tomography Open
Objective : The zebrafish is increasingly used as a small animal model for cardiovascular disease, including vascular disorders. Nevertheless, a comprehensive biomechanical understanding of the zebrafish cardiovascular circulation is still…
View article: Characterizing the cardiovascular phenotype of a new zebrafish model of Marfan syndrome
Characterizing the cardiovascular phenotype of a new zebrafish model of Marfan syndrome Open
Background Marfan syndrome (MFS) is a rare disease caused by a defect in the fibrillin-1 gene (FBN1), with potentially severe cardiovascular manifestations. MFS patients are particularly susceptible to a progressive aortic dilation leading…