Lisa Olsson
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View article: Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation
Identification of human gut bacteria that produce bioactive serotonin and promote colonic innervation Open
The gut microbiota regulates host intestinal serotonin synthesis, thereby promoting the development and maintenance of the enteric nervous system, which controls bowel motility. Functional bowel disorders, including irritable bowel syndrom…
View article: Gut microbiota mediates SREBP-1c-driven hepatic lipogenesis and steatosis in response to zero-fat high-sucrose diet
Gut microbiota mediates SREBP-1c-driven hepatic lipogenesis and steatosis in response to zero-fat high-sucrose diet Open
Sucrose-microbiota interactions and SREBP-1c are required for DNL and hepatic steatosis in the absence of dietary fat. These findings provide new insights into the complex interplay between diet, gut microbiota, and metabolic regulation.
View article: Characterization and description of <i>Clostridium filamentum</i> ETTB, a novel gut bacterium with TLR5 modulating properties
Characterization and description of <i>Clostridium filamentum</i> ETTB, a novel gut bacterium with TLR5 modulating properties Open
The Clostridium genus is highly heterogeneous, encompassing numerous species and strains, many of which remain to be isolated and characterized to better understand their relationship to host physiology. This study aimed to isolate and cha…
View article: Data-driven cluster analysis identifies distinct types of metabolic dysfunction-associated steatotic liver disease
Data-driven cluster analysis identifies distinct types of metabolic dysfunction-associated steatotic liver disease Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) exhibits considerable variability in clinical outcomes. Identifying specific phenotypic profiles within MASLD is essential for developing targeted therapeutic strategies. Her…
View article: An ancient ecospecies of Helicobacter pylori
An ancient ecospecies of Helicobacter pylori Open
View article: Alterations in bile acid kinetics after bariatric surgery in patients with obesity with or without type 2 diabetes
Alterations in bile acid kinetics after bariatric surgery in patients with obesity with or without type 2 diabetes Open
Novo Nordisk Fonden, Leducq Foundation, Swedish Heart-Lung Foundation, Knut and Alice Wallenberg Foundation, the ALF-agreement, ZonMw.
View article: Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism
Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose metabolism Open
Alterations in gut microbiota composition are suggested to contribute to cardiometabolic diseases, in part by producing bioactive molecules. Some of the metabolites are produced by very low abundant bacterial taxa, which largely have been …
View article: ForePass endoscopic bypass device for obesity and insulin resistance—metabolic treatment in a swine model
ForePass endoscopic bypass device for obesity and insulin resistance—metabolic treatment in a swine model Open
View article: The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis
The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis Open
View article: Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in <i>Cyp2c70</i>-deficient mice with a human-like bile acid composition
Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in <i>Cyp2c70</i>-deficient mice with a human-like bile acid composition Open
Mice with deletion of Cyp2c70 have a human-like bile acid composition, display age- and sex-dependent signs of hepatobiliary disease and can be used as a model to study interactions between bile acids and the gut microbiota in cholestatic …
View article: An ancient ecospecies of<i>Helicobacter pylori</i>found in Indigenous populations and animal adapted lineages
An ancient ecospecies of<i>Helicobacter pylori</i>found in Indigenous populations and animal adapted lineages Open
The colonization of our stomachs by Helicobacter pylori is believed to predate the oldest splits between extant human populations. We identify a “Hardy” ecospecies of H. pylori associated with indigenous groups, isolated from people in Sib…
View article: The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis
The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis Open
Dietary lipids can affect metabolic health through gut microbiota-mediated mechanisms, but the influence of lipid-microbiota interaction on liver steatosis is largely unknown. We investigated the impact of dietary lipids on human gut micro…
View article: Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery
Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery Open
Weight loss through bariatric surgery is efficient for treatment or prevention of obesity related diseases such as type 2 diabetes and cardiovascular disease. Long term weight loss response does, however, vary among patients undergoing sur…
View article: Systems analysis of metabolic responses to a mixed meal test in an obese cohort reveals links between tissue metabolism and the gut microbiota
Systems analysis of metabolic responses to a mixed meal test in an obese cohort reveals links between tissue metabolism and the gut microbiota Open
Individuals with prediabetes and type 2 diabetes mellitus (T2DM) have poor ability to adapt to diet-triggered perturbations. We investigated global metabolic responses to a mixed meal test (MMT) in morbidly obese individuals with different…
View article: Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden
Dynamics of the normal gut microbiota: A longitudinal one-year population study in Sweden Open
Temporal dynamics of the gut microbiota potentially limit the identification of microbial features associated with health status. Here, we used whole-genome metagenomic and 16S rRNA gene sequencing to characterize the intra- and inter-indi…
View article: Microbiome and metabolome features of the cardiometabolic disease spectrum
Microbiome and metabolome features of the cardiometabolic disease spectrum Open
View article: Combinatorial, additive and dose-dependent drug–microbiome associations
Combinatorial, additive and dose-dependent drug–microbiome associations Open
View article: Developmental trajectory of the healthy human gut microbiota during the first 5 years of life
Developmental trajectory of the healthy human gut microbiota during the first 5 years of life Open
The gut is inhabited by a densely populated ecosystem, the gut microbiota, that is established at birth. However, the succession by which different bacteria are incorporated into the gut microbiota is still relatively unknown. Here, we ana…
View article: Kvinten i basen. En undersökning om att spela på en kontrabas stämd i kvinter.
Kvinten i basen. En undersökning om att spela på en kontrabas stämd i kvinter. Open
Kvintstämningen har använts flitigt av basister längre tillbaka i tiden, men slutade användas då den ansågs för opraktisk och problematisk. Ändå kan basister idag använda kvintstämning och i denna undersökning har jag undersökt frågor som …
View article: Integration of molecular profiles in a longitudinal wellness profiling cohort
Integration of molecular profiles in a longitudinal wellness profiling cohort Open
View article: The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study
The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study Open
View article: Gut microbiota of obese subjects with Prader-Willi syndrome is linked to metabolic health
Gut microbiota of obese subjects with Prader-Willi syndrome is linked to metabolic health Open
Objective The gut microbiota has been implicated in the aetiology of obesity and associated comorbidities. Patients with Prader-Willi syndrome (PWS) are obese but partly protected against insulin resistance. We hypothesised that the gut mi…
View article: Libraries and Publishers in the Open Science Landscape: Pay, Publish or Perish?
Libraries and Publishers in the Open Science Landscape: Pay, Publish or Perish? Open
Audio from Session 7: Libraries & Publishers in the Open Science Landscape - Pay, Publish or Perish?, held Thursday 27 June 2019 at the LIBER 2019 Annual Conference. Talks included: 7.1 Consequences of Sweden Cancelling Elsevier, …
View article: Consequences of Sweden Cancelling Elsevier
Consequences of Sweden Cancelling Elsevier Open
In May last year, the National Library of Sweden proclaimed that Swedish higher education institutions (HEIs) and government agencies had followed the German example and cancelled their subscriptions with Elsevier. Elsevier had been unable…
View article: Snap out of it! : Samband mellan Snapchat och unga vuxnas välmående: en kvantitativ studie.
Snap out of it! : Samband mellan Snapchat och unga vuxnas välmående: en kvantitativ studie. Open
Sociala medier utgör en stor del av det moderna, globala samhället. Som aldrig förr finns möjlighet att kommunicera med människor världen över. De unga vuxna är framtiden och majoriteten av dem har växt upp i ett teknikpräglat samhälle. I …
View article: Author perspectives on research visibility and impact
Author perspectives on research visibility and impact Open
The poster will present findings from a survey of 375 corresponding authors whose publications have been published open access as part of the Springer Compact agreement between Bibsam and Springer Nature 2016- 2018. In focus is how these a…
View article: Utvärdering av Springer Compact – halvårsrapport 1
Utvärdering av Springer Compact – halvårsrapport 1 Open
View article: Patienters upplevelser av att leva med akut leukemi : En litteraturstudie
Patienters upplevelser av att leva med akut leukemi : En litteraturstudie Open
Introduktion: Leukemi är en cancerform som drabbar benmärgen, detta påverkar tillverkningen av blodkroppar. Att leva med akut leukemi innebär stora förändringar fysiskt, psykiskt och emotionellt. Syfte: Att belysa patienters upplevelser av…
View article: Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimers disease
Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimers disease Open