Lisa Vader
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View article: PhyloNaP: a user-friendly database of Phylogeny for Natural Product–producing enzymes
PhyloNaP: a user-friendly database of Phylogeny for Natural Product–producing enzymes Open
Phylogenetic analysis is widely used to predict enzyme function, yet building annotated and reusable trees is labor-intensive and requires extensive knowledge about the specific enzymes. Existing resources rarely cover biosynthetic enzymes…
View article: antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation
antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation Open
Microorganisms synthesize small bioactive compounds through their secondary or specialized metabolism. Those compounds play an important role in microbial interactions and soil health, but are also crucial for the development of pharmaceut…
View article: PlasmidEC and gplas2: an optimized short-read approach to predict and reconstruct antibiotic resistance plasmids in Escherichia coli
PlasmidEC and gplas2: an optimized short-read approach to predict and reconstruct antibiotic resistance plasmids in Escherichia coli Open
Accurate reconstruction of Escherichia coli antibiotic resistance gene (ARG) plasmids from Illumina sequencing data has proven to be a challenge with current bioinformatic tools. In this work, we present an improved method to reconstruct E…
View article: PlasmidEC and gplas2: An optimised short-read approach to predict and reconstruct antibiotic resistance plasmids in<i>Escherichia coli</i>
PlasmidEC and gplas2: An optimised short-read approach to predict and reconstruct antibiotic resistance plasmids in<i>Escherichia coli</i> Open
Accurate reconstruction of Escherichia coli antibiotic resistance gene (ARG) plasmids from Illumina sequencing data has proven to be a challenge with current bioinformatic tools. In this work, we present an improved method to reconstruct E…
View article: Biosynthesis, evolution and ecology of microbial terpenoids
Biosynthesis, evolution and ecology of microbial terpenoids Open
Terpenoids have diverse bioecological roles in all kingdoms of life. Here we discuss the evolution and ecological functions of microbial terpenoids and their possible applications.