Lisa Zhou
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View article: MLH1 c.27G>A (p.Arg9=) is a synonymous likely/pathogenic variant underlying variably mosaic constitutional MLH1 methylation in Lynch syndrome
MLH1 c.27G>A (p.Arg9=) is a synonymous likely/pathogenic variant underlying variably mosaic constitutional MLH1 methylation in Lynch syndrome Open
View article: Colloid‐Forming Prodrug‐Hydrogel Composite Prolongs Lower Intraocular Pressure in Rodent Eyes after Subconjunctival Injection
Colloid‐Forming Prodrug‐Hydrogel Composite Prolongs Lower Intraocular Pressure in Rodent Eyes after Subconjunctival Injection Open
Colloidal drug aggregates (CDAs) are challenging in drug discovery due to their unpredictable formation and interference with screening assays. These limitations are turned into a strategic advantage by leveraging CDAs as a drug delivery p…
View article: Muir–Torre syndrome in Fitzpatrick skin phototype V assessed by dermoscopy and reflectance confocal microscopy
Muir–Torre syndrome in Fitzpatrick skin phototype V assessed by dermoscopy and reflectance confocal microscopy Open
View article: Toxic epidermal necrolysis-like linear IgA bullous dermatosis as a manifestation of multiple drug hypersensitivity in the setting of drug reaction with eosinophilia and systemic symptoms
Toxic epidermal necrolysis-like linear IgA bullous dermatosis as a manifestation of multiple drug hypersensitivity in the setting of drug reaction with eosinophilia and systemic symptoms Open
View article: Pseudokebnorization of leprosy: A unique phenomenon from mpox virus coinfection
Pseudokebnorization of leprosy: A unique phenomenon from mpox virus coinfection Open
View article: MLH1-methylated endometrial cancer under 60 years of age as the “sentinel” cancer in female carriers of high-risk constitutional MLH1 epimutation
MLH1-methylated endometrial cancer under 60 years of age as the “sentinel” cancer in female carriers of high-risk constitutional MLH1 epimutation Open
View article: Supplementary Tables for "The proteomic skin profile of moderate-to-severe atopic dermatitis shows an inflammatory and cardiovascular signature"
Supplementary Tables for "The proteomic skin profile of moderate-to-severe atopic dermatitis shows an inflammatory and cardiovascular signature" Open
This data extends the “inflammation map” of atopic dermatitis, which has been created largely through gene expression profiling. It suggests that risk proteins found in blood are primarily derived from skin. Early treatment of skin inflamm…
View article: An enhancer:involucrin regulatory module impacts human skin barrier adaptation out-of-Africa and modifies atopic dermatitis risk
An enhancer:involucrin regulatory module impacts human skin barrier adaptation out-of-Africa and modifies atopic dermatitis risk Open
The genetic modules that contribute to human evolution are poorly understood. We identified positive selection for two independent involucrin ( IVL ) haplotypes in European (CEU) and Asian (JPT/CHB) populations for skin epidermis. CEU IVL …
View article: GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis
GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis Open
Two doses of GBR 830 administered 4 weeks apart were well tolerated and induced significant progressive tissue and clinical changes until day 71 (42 days after the last dose), highlighting the potential of OX40 targeting in patients with A…
View article: Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis
Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis Open
View article: GBR 830 Induced Progressive and Sustained Improvements in Atopic Dermatitis Skin Biomarkers and Clinical Parameters
GBR 830 Induced Progressive and Sustained Improvements in Atopic Dermatitis Skin Biomarkers and Clinical Parameters Open
not available. Disclosures: Study sponsored by Glenmark Pharmaceuticals. Copyright 2018 SKIN
View article: Dovitinib and erlotinib in patients with metastatic non-small cell lung cancer: A drug–drug interaction
Dovitinib and erlotinib in patients with metastatic non-small cell lung cancer: A drug–drug interaction Open