Lisandro D. Colantonio
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View article: Prevention of Cardiovascular Disease Events and Deaths Among Black Adults Via Systolic Blood Pressure Equity
Prevention of Cardiovascular Disease Events and Deaths Among Black Adults Via Systolic Blood Pressure Equity Open
Importance There are disparities in blood pressure (BP) levels by race in the US. Objective To estimate the number of cardiovascular disease (CVD) events and deaths that could be prevented among non-Hispanic Black adults by achieving the s…
View article: Role of hypertension in the cardiovascular-kidney-metabolic syndrome among black adults: The Jackson Heart Study
Role of hypertension in the cardiovascular-kidney-metabolic syndrome among black adults: The Jackson Heart Study Open
The cardiovascular-kidney-metabolic (CKM) syndrome consists of four progressive stages and is characterized by the interaction of metabolic risk factors, chronic kidney disease (CKD), and cardiovascular disease (CVD). We assessed the preva…
View article: Cardiovascular Risk Prediction in Older Adults
Cardiovascular Risk Prediction in Older Adults Open
View article: Comparison of Short‐ and Long‐Term Cardiovascular Disease Risk Assessment Tools in US Young Adults
Comparison of Short‐ and Long‐Term Cardiovascular Disease Risk Assessment Tools in US Young Adults Open
Background In 2023, the American Heart Association published the Predicting Risk of Cardiovascular Disease Events (PREVENT) equations for estimating atherosclerotic cardiovascular disease (ASCVD) risk in adults aged 30 to 79 years. We comp…
View article: Aspirin use and the risk for cardiovascular disease by lipoprotein(a) levels: a multi-cohort study
Aspirin use and the risk for cardiovascular disease by lipoprotein(a) levels: a multi-cohort study Open
Aims Small observational studies suggest that aspirin use may be associated with a 50% lower incidence of cardiovascular disease (CVD) in adults with lipoprotein(a) ≥ 50 mg/dL, without apparent benefit in those with lipoprotein(a) < 50 …
View article: Development and Validation of an Incident Hypertension Risk Prediction Model for Young Adults
Development and Validation of an Incident Hypertension Risk Prediction Model for Young Adults Open
Background Identifying young adults at high risk of hypertension can improve blood pressure screening recommendations. Methods We developed models to predict incident hypertension using diverse contemporary cohorts of young adults aged 18 …
View article: Development and Validation of Models to Estimate the Incident Risk of Cognitive Impairment and Atherosclerotic Cardiovascular Disease in Older Adults
Development and Validation of Models to Estimate the Incident Risk of Cognitive Impairment and Atherosclerotic Cardiovascular Disease in Older Adults Open
Background Guidelines emphasize using atherosclerotic cardiovascular disease (ASCVD) risk prediction models for treatment decisions, but risk of cognitive impairment is an equally important concern in older adults. Current ASCVD risk predi…
View article: Evaluation and Comparison of the PREVENT and Pooled Cohort Equations for 10‐Year Atherosclerotic Cardiovascular Risk Prediction
Evaluation and Comparison of the PREVENT and Pooled Cohort Equations for 10‐Year Atherosclerotic Cardiovascular Risk Prediction Open
Background We compared the atherosclerotic cardiovascular disease (ASCVD) risk prediction performance of the American Heart Association's Predicting Risk of Cardiovascular Disease Events (PREVENT) Base and PREVENT Full equations (includes …
View article: Risk-enhancing factors and social determinants of health in risk assessment for atherosclerotic cardiovascular disease
Risk-enhancing factors and social determinants of health in risk assessment for atherosclerotic cardiovascular disease Open
Background The Pooled Cohort Equations (PCEs) do not accurately estimate atherosclerotic cardiovascular disease (ASCVD) risk in certain populations. The 2018 AHA/ACC cholesterol guideline identified risk-enhancing factors as a supplement t…
View article: Associations among claims-based care fragmentation, self-reported gaps in care coordination, and self-reported adverse events
Associations among claims-based care fragmentation, self-reported gaps in care coordination, and self-reported adverse events Open
Medicare beneficiaries with claims-based fragmentation also report gaps in communication among their providers. Moreover, these gaps appear to be clinically significant, with beneficiaries reporting adverse events that they attribute to po…
View article: Persistence and Adherence to PCSK9 Inhibitor Monoclonal Antibodies Versus Ezetimibe in Real-World Settings
Persistence and Adherence to PCSK9 Inhibitor Monoclonal Antibodies Versus Ezetimibe in Real-World Settings Open
View article: Cardiovascular Risk Associated With Social Determinants of Health at Individual and Area Levels
Cardiovascular Risk Associated With Social Determinants of Health at Individual and Area Levels Open
Importance The benefit of adding social determinants of health (SDOH) when estimating atherosclerotic cardiovascular disease (ASCVD) risk is unclear. Objective To examine the association of SDOH at both individual and area levels with ASCV…
View article: Comparing PCSK9 Monoclonal Antibody Treatment Strategies Following Myocardial Infarction Using Negative Control Outcomes: A Target Trial Emulation Study
Comparing PCSK9 Monoclonal Antibody Treatment Strategies Following Myocardial Infarction Using Negative Control Outcomes: A Target Trial Emulation Study Open
Background: Initiation of proprotein convertase subtilisin/kexin type 9 monoclonal antibody (PCSK9 mAb) for lipid-lowering following myocardial infarction (MI) is likely affected by patients’ prognostic factors, potentially leading to bias…
View article: Trends in the Prevalence of Multiple Chronic Conditions Among US Adults With Hypertension From 1999–2000 Through 2017–2020
Trends in the Prevalence of Multiple Chronic Conditions Among US Adults With Hypertension From 1999–2000 Through 2017–2020 Open
BACKGROUND The prevalence of many chronic conditions has increased among US adults. Many adults with hypertension have other chronic conditions. METHODS We estimated changes in the age-adjusted prevalence of multiple (≥3) chronic condition…
View article: Association Between Young Adult Characteristics and Blood Pressure Trajectories
Association Between Young Adult Characteristics and Blood Pressure Trajectories Open
Background Blood pressure (BP) trajectories from young adulthood through middle age are associated with cardiovascular risk. We examined the associations of hypertension risk factors with BP trajectories among a large diverse sample. Metho…
View article: Self-stigma, career development and employment in young adults with ASD in Chile.
Self-stigma, career development and employment in young adults with ASD in Chile. Open
Introduction Stigma describes prejudicial attitudes, negative stereotypes, and discrimination targeting a subgroup. Various forms of stigma have been identified in the literature, including self-stigma. Self-stigma or internalized stigma o…
View article: Ambulatory Care Fragmentation and Total Health Care Costs
Ambulatory Care Fragmentation and Total Health Care Costs Open
Background: The magnitude of the relationship between ambulatory care fragmentation and subsequent total health care costs is unclear. Objective: To determine the association between ambulatory care fragmentation and total health care cost…
View article: Low-Density Lipoprotein Cholesterol Testing Following Myocardial Infarction Hospitalization Among Medicare Beneficiaries
Low-Density Lipoprotein Cholesterol Testing Following Myocardial Infarction Hospitalization Among Medicare Beneficiaries Open
LDL-C testing following MI hospital discharge among Medicare beneficiaries was low.
View article: Risk Prediction for Atherosclerotic Cardiovascular Disease With and Without Race Stratification
Risk Prediction for Atherosclerotic Cardiovascular Disease With and Without Race Stratification Open
Importance Use of race-specific risk prediction in clinical medicine is being questioned. Yet, the most commonly used prediction tool for atherosclerotic cardiovascular disease (ASCVD)—pooled cohort risk equations (PCEs)—uses race stratifi…
View article: Atherosclerotic cardiovascular disease events among adults with high predicted risk without established risk factors
Atherosclerotic cardiovascular disease events among adults with high predicted risk without established risk factors Open
Adults with a 10-year predicted ASCVD risk ≥7.5 % but without established risk factors had a high ASCVD incidence.
View article: Lipoprotein(a) and the Risk for Recurrent Ischemic Stroke Events
Lipoprotein(a) and the Risk for Recurrent Ischemic Stroke Events Open
View article: Diabetes, Gaps in Care Coordination, and Preventable Adverse Events
Diabetes, Gaps in Care Coordination, and Preventable Adverse Events Open
Interventions to improve quality of care for patients with diabetes could incorporate patient-reported gaps in care coordination to aid in preventing adverse events.
View article: Lipoprotein(a) and the Risk for Recurrent Atherosclerotic Cardiovascular Events Among Adults With CKD: The Chronic Renal Insufficiency Cohort (CRIC) Study
Lipoprotein(a) and the Risk for Recurrent Atherosclerotic Cardiovascular Events Among Adults With CKD: The Chronic Renal Insufficiency Cohort (CRIC) Study Open
View article: Hypertension Statistics for US Adults: An Open-Source Web Application for Analysis and Visualization of National Health and Nutrition Examination Survey Data
Hypertension Statistics for US Adults: An Open-Source Web Application for Analysis and Visualization of National Health and Nutrition Examination Survey Data Open
Background: Data from the US National Health and Nutrition Examination Survey are freely available and can be analyzed to produce hypertension statistics for the noninstitutionalized US population. The analysis of these data requires stati…
View article: Understanding socio-labor inclusion among young adults with autism spectrum and mental disorders: preliminary findings
Understanding socio-labor inclusion among young adults with autism spectrum and mental disorders: preliminary findings Open
Introduction Previous studies suggest that adults with mental disorders (MD) or Autism Spectrum Disorder (ASD) are more likely to be unemployed than those without MD. However, it is unclear whether working adults with MD or ASD perceive th…
View article: Association Between Triglycerides and Incident Cognitive Impairment in Black and White Adults in the Reasons for Geographic and Racial Differences in Stroke Study
Association Between Triglycerides and Incident Cognitive Impairment in Black and White Adults in the Reasons for Geographic and Racial Differences in Stroke Study Open
Background Elevated nonfasting triglycerides were associated with non‐Alzheimer dementia in a recent study. However, this study neither evaluated the association of fasting triglycerides with incident cognitive impairment (ICI) nor adjuste…
View article: Real-World Implications of the American Gastroenterology Association Nonalcoholic Fatty Liver Disease Clinical Care Pathway in the US Adult Population
Real-World Implications of the American Gastroenterology Association Nonalcoholic Fatty Liver Disease Clinical Care Pathway in the US Adult Population Open
View article: Ambulatory Care Fragmentation, Emergency Department Visits, and Race: a Nationwide Cohort Study in the U.S.
Ambulatory Care Fragmentation, Emergency Department Visits, and Race: a Nationwide Cohort Study in the U.S. Open
View article: Recurrent atherosclerotic cardiovascular disease events preventable with guideline recommended lipid-lowering treatment following myocardial infarction
Recurrent atherosclerotic cardiovascular disease events preventable with guideline recommended lipid-lowering treatment following myocardial infarction Open
Background The 2018 American Heart Association/American College of Cardiology (AHA/ACC) cholesterol guideline provides recommendations for lipid-lowering therapy (LLT) including statins, ezetimibe and proprotein convertase subtilisin/kexin…
View article: Estimated number and percentage of US adults with atherosclerotic cardiovascular disease recommended add-on lipid-lowering therapy by the 2018 AHA/ACC multi-society cholesterol guideline
Estimated number and percentage of US adults with atherosclerotic cardiovascular disease recommended add-on lipid-lowering therapy by the 2018 AHA/ACC multi-society cholesterol guideline Open