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View article: Differential contributions of the gut microbiota and metabolome to pathomechanisms in ulcerative colitis: an <i>in vitro</i> analysis
Differential contributions of the gut microbiota and metabolome to pathomechanisms in ulcerative colitis: an <i>in vitro</i> analysis Open
The gut microbiota has been implicated in onset and progression of ulcerative colitis (UC). Here, we assess potential causal involvement of the microbiota and -associated fecal water (FW) metabolome in altering key functional parameters of…
View article: Wheat bran with reduced particle size increases serum SCFAs in obese subjects without improving health parameters compared with a maltodextrin placebo
Wheat bran with reduced particle size increases serum SCFAs in obese subjects without improving health parameters compared with a maltodextrin placebo Open
View article: Accuracy of Nutrient Calculations Using the Consumer-Focused Online App MyFitnessPal: Validation Study
Accuracy of Nutrient Calculations Using the Consumer-Focused Online App MyFitnessPal: Validation Study Open
Background Digital food registration via online platforms that are coupled to large food databases obviates the need for manual processing of dietary data. The reliability of such platforms depends on the quality of the associated food dat…
View article: Accuracy of Nutrient Calculations Using the Consumer-Focused Online App MyFitnessPal: Validation Study (Preprint)
Accuracy of Nutrient Calculations Using the Consumer-Focused Online App MyFitnessPal: Validation Study (Preprint) Open
BACKGROUND Digital food registration via online platforms that are coupled to large food databases obviates the need for manual processing of dietary data. The reliability of such platforms depends on the quality of the associated food da…
View article: Dietary assessment with the online platform MyFitnessPal: a reliable method?
Dietary assessment with the online platform MyFitnessPal: a reliable method? Open
A major challenge in dietary assessment is the manual pre-processing of dietary data. Digital food registration via online platforms that are coupled to large food databases can automate this process. The accuracy of such platforms depends…
View article: P774 Metagenomics and metabolomics of patients with inflammatory bowel disease and their unaffected relatives
P774 Metagenomics and metabolomics of patients with inflammatory bowel disease and their unaffected relatives Open
Background: Dysbiosis, intestinal barrier dysfunction and metabolic alterations of the gut microbiota have been implicated in the pathogenesis of inflammatory bowel disease. We studied the faecal microbiome and metabolome, as well a…
View article: Wheat Bran Does Not Affect Postprandial Plasma Short-Chain Fatty Acids from 13C-inulin Fermentation in Healthy Subjects
Wheat Bran Does Not Affect Postprandial Plasma Short-Chain Fatty Acids from 13C-inulin Fermentation in Healthy Subjects Open
Wheat bran (WB) is a constituent of whole grain products with beneficial effects for human health. Within the human colon, such insoluble particles may be colonized by specific microbial teams which can stimulate cross-feeding, leading to …
View article: Systemic availability and metabolism of colonic‐derived short‐chain fatty acids in healthy subjects: a stable isotope study
Systemic availability and metabolism of colonic‐derived short‐chain fatty acids in healthy subjects: a stable isotope study Open
Key points The short‐chain fatty acids (SCFAs) are bacterial metabolites produced during the colonic fermentation of undigested carbohydrates, such as dietary fibre and prebiotics, and can mediate the interaction between the diet, the micr…
View article: Quantification of in Vivo Colonic Short Chain Fatty Acid Production from Inulin
Quantification of in Vivo Colonic Short Chain Fatty Acid Production from Inulin Open
Short chain fatty acids (SCFA), including acetate, propionate, and butyrate, are produced during bacterial fermentation of undigested carbohydrates in the human colon. In this study, we applied a stable-isotope dilution method to quantify …
View article: Contribution of Colonic Fermentation and Fecal Water Toxicity to the Pathophysiology of Lactose-Intolerance
Contribution of Colonic Fermentation and Fecal Water Toxicity to the Pathophysiology of Lactose-Intolerance Open
Whether or not abdominal symptoms occur in subjects with small intestinal lactose malabsorption might depend on differences in colonic fermentation. To evaluate this hypothesis, we collected fecal samples from subjects with lactose malabso…
View article: 397 Colonic Derived Propionate As Substrate for Gluconeogenesis: An In Vivo Stable Isotope Study in Humans
397 Colonic Derived Propionate As Substrate for Gluconeogenesis: An In Vivo Stable Isotope Study in Humans Open
View article: Mo1800 Colonic Luminal Compounds Do Not Affect Butyrate Metabolism in Ulcerative Colitis
Mo1800 Colonic Luminal Compounds Do Not Affect Butyrate Metabolism in Ulcerative Colitis Open