Explanipedia

Associations between dietary patterns and the incidence of idiopathic pulmonary fibrosis: A cohort study Open

Yonghao Li, Xinran Dou, Hui Li, Li Xuan, Luqin Yang , et al. · 2025

Enhancing the physicochemical and textural properties of goat milk yogurt using Cordyceps militaris polysaccharide and polymerized whey protein composite hydrogels Open

Xingyu Zhang, Lifen Liu, Wenwen Chen, Huiyu Xiang, Weibing Tao , et al. · 2025

Thermochemical conversion of waste into energy: a review Open

Cui Quan, Voninirina Safidy Ravelomanantsoa, Leire Olazar, Laura Santamaria, Gartzen López , et al. · 2025

The increasing global energy demand, the decline in fossil fuels and the growing amount of municipal solid waste are major environmental and socioeconomic issues, calling for advanced techniques to recycle waste into energy. Here, we revie…

On the Translation of Vague Language in International Business Negotiations from the Perspective of Intercultural Communication Open

Rumeng Li, Lifen Liu · 2025

Successful international business negotiations are vital for the integration of the global economy. To avoid misunderstandings that can harm both parties, it’s crucial to communicate with precision and clarity. However, vagueness can somet…

Development and mechanism study of functional fermentation media for reducing alkaloid content in cigar tobacco leaves Open

Wanrong Hu, Lifen Liu, Jiabao Zhang, Quanwei Zhou, Zhongrong Jiang , et al. · 2025

Background Elevated alkaloid levels in tobacco leaves can cause significant irritation and a pronounced bitterness. Fermentation is a well-recognized strategy to reduce alkaloid content. However, its effectiveness is influenced by the choi…

Targeting G1–S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors Open

Shilpa Singh, Catherine E. Gleason, Min Fang, Yasmin Nabil Laimon, Vishal Khivansara , et al. · 2025

Small-cell lung cancers (SCLCs) contain near-universal loss-of-function mutations in RB1 and TP53, compromising the G1-S checkpoint and leading to dysregulated E2F activity¹. Other cancers similarly disrupt the G1-S checkpoint t…

Design and Flow Characteristics of a Gravity-Driven Flow Control Valve Open

Qing Wang, Jun Qu, Lifen Liu, Xiaoming Tan, Jianhua Guo , et al. · 2025

Ultra-high-temperature and pressure downhole environments pose challenges for conventional electronic instruments to adapt to high-temperature formations, thereby restricting the application of downhole electronic tool technology in deep a…

A Study on the Optimization and Sensitivity Analysis of Cuttings Transport in Large-Diameter Boreholes Open

Qing Wang, Lifen Liu, Jiawei Zhang, Jianhua Guo, Xiaoao Liu , et al. · 2025

In the drilling process of ultra-deep wells with large-diameter boreholes, the transport and deposition behavior of cuttings plays a critical role in maintaining wellbore cleanliness and ensuring operational safety. Due to the geometry of …

Early identification of apple bitter pit using hyperspectral imaging technology Open

Dong Chen, Tianyi Yang, Lifen Liu, Zhifeng Wei, Caiyun Shi , et al. · 2025

Iguratimod Attenuates Diabetic Cognitive Impairment via Suppressing B Cell Activation and CD8+ T Cell Cytotoxicity Open

Qingsheng Yin, Ruibing Su, Xiaolu Nie, Ping Liu, Jie Bu , et al. · 2025

Research on Cuttings Transport Behavior in the 32-Inch Borehole of a 10,000-Meter-Deep Well Open

Qing Wang, Lifen Liu, Lei Xia, Jiawei Zhang, Xusheng He , et al. · 2025

During the drilling processes of a 10,000-meter-deep well, cutting removal becomes difficult in the 32-inch borehole, which significantly increases downhole risks and affects drilling efficiency. To address this, a numerical simulation met…

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47 Open

Zhengfang Liu, Xiumei Zhao, Maolin Zang, Huiyang Yuan, Xin Qin , et al. · 2025

Cancer cell‐intrinsic features (e.g., genetic aberrations and dysregulation of signaling pathways) play pivotal roles in orchestrating the composition and functional state of the immune landscape, which in turn impact tumor progression and…

Spin‐Splitting Magnetoresistance in Altermagnetic RuO<sub>2</sub> Thin Films Open

Hongyu Chen, Zian Wang, Peixin Qin, Ziang Meng, Xiaorong Zhou , et al. · 2025

The recently discovered altermagnets, featured by the exotic correlation of magnetic exchange interaction and alternating crystal environments, have offered exciting cutting‐edge opportunities for spintronics. Nevertheless, the altermagnet…

Neuroplastin 65 deficiency leads to the impairment of visual function through affecting ribbon synapse in retina of mice Open

Jiujiang Zeng, Ling Chen, Lifen Liu, Jialu Wang, Jie Cheng , et al. · 2025

Neuroplastin 65 (NP65) is a synapse-enriched glycoprotein in the central nervous system and is implicated in synaptic plasticity. In the present study, we found that NP65 knockout (NP65 KO) mice exhibit impaired visual function, including …

Association of functional disability with cardiometabolic disease status in a national cohort study Open

Ping Ni, Fang Wang, Lifen Liu, Meiling Ge, Xiuying Hu · 2025

Curcumin induces mitochondrial dysfunction-associated oxidative DNA damage in ovarian cancer cells Open

Qi Bao, Zihan Wang, Tingting Yang, Xiaojuan Su, Ying Chen , et al. · 2025

Resistance to chemotherapeutic agents is a critical challenge for the clinical management of ovarian cancer. While curcumin has been reported to possess anti-cancer properties, how it exerts its anti-neoplastic effect on ovarian cancer cel…

Precise engineering of gene expression by editing plasticity Open

Yang Qiu, Lifen Liu, Jiali Yan, Xianglei Xiang, Shouzhe Wang , et al. · 2025

Our study provides a robust computational framework that advances knowledge-guided gene editing for precise regulation of gene expression and crop improvement. By reliably predicting and validating CREs, we offer a tool for targeted geneti…

Evaluation of efficacy and safety of AAV8-ΔC4ATP7B gene therapy in a mutant mouse model of Wilson’s disease Open

Chunhua Zeng, Yunting Lin, Xinshuo Lu, Shehong Chen, Yan Xia , et al. · 2025

Experimental Investigation of Factors Influencing Spontaneous Imbibition in Shale Reservoirs Open

Lifen Liu, Yimin Wang, Aiwei Zheng, Jiqing Li, Qian Zhang , et al. · 2025

The flowback rate of fracturing fluid in shale reservoirs is often notably low, primarily due to the spontaneous imbibition of the water-based fracturing fluid. Despite their significance, the factors influencing spontaneous imbibition in …

Integrated Design of Superhydrophobic Structures and Functions of Zr46cu46al8 Metallic Glass Surfaces Open

Guanzhong Ding, Guoyang Zhang, Ranfeng Wei, Yujia Wang, Rui Zheng , et al. · 2025

Integrated Design of Superhydrophobic Structures and Functions of Zr46cu46al8 Metallic Glass Surfaces Open

Guanzhong Ding, Guoyang Zhang, Ranfeng Wei, Yujia Wang, Rui Zheng , et al. · 2025

Pani-Ti3c2tx-Doped Qppo Membranes for Enhanced Separation of H+/Metal Cations and Li+/Mg2+ Open

Haofang Wang, Zhifei Wu, Xu Zhang, Lifen Liu, Deqing Liu , et al. · 2025

DeePoly: A High-Order Accuracy Scientific Machine Learning Framework for Function Approximation and Solving PDEs Open

Lifen Liu, Heng Yong · 2025

Recently, machine learning methods have gained significant traction in scientific computing, particularly for solving Partial Differential Equations (PDEs). However, methods based on deep neural networks (DNNs) often lack convergence guara…

Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses Open

Lifen Liu, Yang Liu, Rui Li, Yue Teng, Shuyang Zhao , et al. · 2025

Background Post‐traumatic stress disorder (PTSD) is a complex psychiatric condition that emerges following exposure to trauma and significantly affects daily functioning. Current research is focused on identifying effective treatments for …

Evaluation of nutrient composition and bone-promoting activity of miiuy croaker (Miichthys miiuy) bone Open

Qianqian Ouyang, Lifen Liu, Lili Liu, Yi Li, Yi Qi , et al. · 2024

Introduction The objective of this study was to improve the economic value of the processed by-products of farmed miiuy croaker ( Miichthys miiuy ) by evaluating the nutrient composition and osteogenic activity of its bones. We prepared Mi…

Potential application of all-solid waste belite-ye'elimite cement in high early-strength pavement concrete: Strength formation, characterization, and benefit evaluation Open

Cunyong Sun, Zhang Ju, Changwang Yan, Lifen Liu, Jihui Zhao , et al. · 2024

Nutrient composition analysis and quality evaluation system construction of Litopenaeus vannamei from different aquaculture water environments Open

Lifen Liu, Yali Yu, Yingchun Mu, Jinhua Xu, Zhen Yang , et al. · 2024

Litopenaeus vannamei was one of the shrimp varieties with the highest output at present in China. In this study, nutrition indexes including moisture, ash, protein, fat, amino acid and fatty acid of Litopenaeus vannamei from seawater, sali…

Widely targeted metabolomics and SPME-GC-MS analysis revealed the quality characteristics of non-volatile/volatile compounds in Zheng’an Bai tea Open

Lifen Liu, Dahe Qiao, Xiaozeng Mi, Shirui Yu, Tingting Jing , et al. · 2024

Background As albino tea under the geographical protection of agricultural products, Zheng’an Bai tea is not only rich in amino acids, polyphenols and other beneficial components for the human body, but also its leaf color will turn green …

Activation of mGluR2/3 by LY379268 alleviates PTSD fear memories by down-regulating the CaMKII/CREB signaling pathway in the amygdala Open

Rui Li, Li Yu, Lifen Liu, Shiqi Liu, Haohan Sang , et al. · 2024

Background People with post-traumatic stress disorder (PTSD) have recurrent memory flashbacks of traumatic events, leading to severe symptoms of anxiety and even phobias. Targeted drug staging interventions may eliminate or alleviate fear …

Preparation and characterization of Sipunculus nudus peptide-calcium chelate: Structural insights and osteogenic bioactivity assessment Open

Qianqian Ouyang, Yuwei Jiang, Lifen Liu, Chengfeng Cai, Nandika Bandara , et al. · 2024

In order to prepare calcium supplements for efficient absorption and utilization in the human body, this study focused on synthesizing SNP-Ca by chelating Squarrosus nudus peptide (SNP) with calcium. We characterized its structure, stabili…

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