Liwen Liu
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View article: Evaluating the Consistency of Remote Versus In-person Evaluation Strategies in Objective Structured Clinical Examinations
Evaluating the Consistency of Remote Versus In-person Evaluation Strategies in Objective Structured Clinical Examinations Open
View article: Alterations in the serum metabolome in patients with the COVID-19 Omicron variant and in recovered cases
Alterations in the serum metabolome in patients with the COVID-19 Omicron variant and in recovered cases Open
Corona Virus Disease (COVID-19) has become a global public health crisis, and the Omicron variant has rapidly taken over as soon as it was detected Serum circulating metabolites can provide extensive insights into the pathogenesis and diag…
View article: Dynamic alterations of oral fungal microbiota in Omicron infected patients
Dynamic alterations of oral fungal microbiota in Omicron infected patients Open
Oral fungal microbiota plays an important role in many diseases, however, the role of oral fungal microorganisms in the development of patients infected with Omicron has not been reported. A total of 963 tongue coating samples were prospec…
View article: Interpreting the Spatial Characteristics of the Dike-Pond System through Deep Learning and Digital Mapping Techniques: A Case Study of Foshan Sangyuanwei
Interpreting the Spatial Characteristics of the Dike-Pond System through Deep Learning and Digital Mapping Techniques: A Case Study of Foshan Sangyuanwei Open
The Dike-Pond System in China’s Pearl River Delta is a distinctive form of agricultural heritage, renowned for its integrated land-water production, ecological adaptability, and embedded cultural practices. Despite growing recognition of i…
View article: TutorBench: A Benchmark To Assess Tutoring Capabilities Of Large Language Models
TutorBench: A Benchmark To Assess Tutoring Capabilities Of Large Language Models Open
As students increasingly adopt large language models (LLMs) as learning aids, it is crucial to build models that are adept at handling the nuances of tutoring: they need to identify the core needs of students, be adaptive, provide personal…
View article: Theoretical perspectives on submandibular gland preservation in head and neck cancer surgery: a pre-research review
Theoretical perspectives on submandibular gland preservation in head and neck cancer surgery: a pre-research review Open
In the neck dissection procedures for head and neck squamous cell carcinoma (HNSCC), the submandibular gland (SMG) is frequently and routinely removed. However, is the sacrifice of the SMG truly indispensable? We have analyzed this issue f…
View article: Effects of rapid recovery nursing after surgery in patients with acute calculous cholecystitis after laparoscopic cholecystectomy
Effects of rapid recovery nursing after surgery in patients with acute calculous cholecystitis after laparoscopic cholecystectomy Open
BACKGROUND Laparoscopic cholecystectomy (LC) is the primary treatment for acute calculous cholecystitis. Although rapid recovery nursing is commonly implemented in postoperative care, its effect on acute calculous cholecystitis after LC re…
View article: Retraction Note: Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer
Retraction Note: Long non-coding RNA PVT1 promotes tumor progression by regulating the miR-143/HK2 axis in gallbladder cancer Open
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12943-019-0947-9.
View article: RHBDF2 governs microglial neuroinflammation during cerebral ischemia–reperfusion injury and is positively regulated by the m6A reader YTHDF1
RHBDF2 governs microglial neuroinflammation during cerebral ischemia–reperfusion injury and is positively regulated by the m6A reader YTHDF1 Open
Background Neuroinflammation mediated by microglia activation is the key pathological mechanisms for cerebral ischemia–reperfusion injury (CIRI). This study investigated the role and underlying molecular mechanism of Rhomboid 5 homolog 2 (…
View article: Multimodal Psychobehavioral Interventions for Lung Cancer–Related Pain: A Protocol Development and Validation Study Examining the Mediating Role of Self-Efficacy in the Relationship Between Pain Perception and Adaptive Coping Strategies
Multimodal Psychobehavioral Interventions for Lung Cancer–Related Pain: A Protocol Development and Validation Study Examining the Mediating Role of Self-Efficacy in the Relationship Between Pain Perception and Adaptive Coping Strategies Open
A comprehensive, multimodal intervention significantly improved both pain control and self-efficacy in patients with lung cancer-related pain. The effects were robust across demographic subgroups, with pain relief being a key factor influe…
View article: The tumor suppressor DACT3 sensitizes triple-negative breast cancer to apatinib by inhibiting the Wnt/β-catenin pathway
The tumor suppressor DACT3 sensitizes triple-negative breast cancer to apatinib by inhibiting the Wnt/β-catenin pathway Open
Apatinib, a small-molecule inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2), shows efficient antitumor activity in heavily pretreated metastatic triple-negative breast cancer (TNBC). However, not all patients respond to …
View article: Origins of blue and violet luminescence in AlN films grown by MOCVD and the impact of a small amount of Ga doping
Origins of blue and violet luminescence in AlN films grown by MOCVD and the impact of a small amount of Ga doping Open
Aluminum nitride (AlN) has attracted considerable attention for its promising applications in short-wavelength optoelectronic devices. However, undesirable blue and violet luminescence from MOCVD-grown AlN films has impeded their developme…
View article: Renal function affects the plasma concentration and hematological toxicity of linezolid in elderly patients: a propensity-matched cohort analysis
Renal function affects the plasma concentration and hematological toxicity of linezolid in elderly patients: a propensity-matched cohort analysis Open
Background The relationships of renal function with linezolid trough concentration (Cmin) and hematological toxicity have not been clarified in elderly patients. Methods In this propensity-matched cohort analysis, elderly patients receivin…
View article: Fertility preserving radical cervical cancer surgery: A case report
Fertility preserving radical cervical cancer surgery: A case report Open
View article: Correlation Between Retinal Vascular Oxygen Saturation, Red Blood Cell Parameters and Hemorheology Parameters in Healthy Adults
Correlation Between Retinal Vascular Oxygen Saturation, Red Blood Cell Parameters and Hemorheology Parameters in Healthy Adults Open
The relationship between retinal blood oxygen saturation and red blood cell and hemorheology parameters confirmed the close correlation between ocular microcirculation and systemic blood circulation, which provided a prospective diagnosis …
View article: Exploring the Metabolic Pathways of Melon (Cucumis melo L.) Yellow Leaf Mutants via Metabolomics
Exploring the Metabolic Pathways of Melon (Cucumis melo L.) Yellow Leaf Mutants via Metabolomics Open
A yellow leaf mutant named ‘ZT00091’ was discovered during the cultivation of the melon variety ‘ZT091’. An analysis of the leaf ultrastructure revealed that the chloroplasts of ‘ZT00091’ were significantly smaller than those of ‘ZT091’, w…
View article: Improved mRNA-based RSV vaccine with PreF forming enveloped virus-like particles
Improved mRNA-based RSV vaccine with PreF forming enveloped virus-like particles Open
View article: Associations between oxidative balance score and chronic kidney disease events in type 2 diabetes mellitus patients: a cross‑sectional study
Associations between oxidative balance score and chronic kidney disease events in type 2 diabetes mellitus patients: a cross‑sectional study Open
View article: Podocyte TLR4 deletion alleviates diabetic kidney disease through prohibiting PKCδ/SHP-1-dependent ER stress and relieving podocyte damage and inflammation
Podocyte TLR4 deletion alleviates diabetic kidney disease through prohibiting PKCδ/SHP-1-dependent ER stress and relieving podocyte damage and inflammation Open
These findings elucidated the involvement of the TLR4/MyD88/PKCδ/SHP-1 signaling cascade in diabetic podocyte injury and inflammation, provided evidence for the renal protective and therapeutic potential of podocyte-specific targeting TLR4…
View article: Preparation of Nanoporous Cobalt‐Iron Alloys From Samarium‐Cobalt Magnet Scraps and the Performance Evaluation as the Oxygen Evolution Reaction Electrocatalysts
Preparation of Nanoporous Cobalt‐Iron Alloys From Samarium‐Cobalt Magnet Scraps and the Performance Evaluation as the Oxygen Evolution Reaction Electrocatalysts Open
Samarium‐cobalt (SmCo) magnets are available for critical use in aircraft, microwaves, magnetic couplings, missiles, and electrical engineering products. This work presents a new method for adeptly transforming SmCo scraps into oxygen evol…
View article: Radiation-Based Multi-Modal Therapy Combining with Immunotherapy to Develop a Vaccine-Like Effective Treatment for Triple-Negative Breast Cancer
Radiation-Based Multi-Modal Therapy Combining with Immunotherapy to Develop a Vaccine-Like Effective Treatment for Triple-Negative Breast Cancer Open
Based on the 4T1 mouse model, developed an effective vaccine-like therapeutic strategy combining X-PDT with Anti-CTLA4, which can effectively ablate tumors, inhibit metastasis, and prevent tumor recurrence. This work may provide a novel ef…
View article: Optimization design of boriding process prediction algorithm based on multiple linear regression model
Optimization design of boriding process prediction algorithm based on multiple linear regression model Open
The boronizing process of the 20CrMo surface is a complex process of mu1ti-variable interaction. The quality of the boronizing layer is affected by the heating method, boronizing temperature, boronizing time, and cooling method. Therefore,…
View article: Care coordination and patient safety outcome: a graph-based approach
Care coordination and patient safety outcome: a graph-based approach Open
Predicting postoperative adverse events and managing the associated risk factors is crucial for patient safety. Care coordination, also known as provider team interactions, significantly impacts outcomes, yet few studies have explored this…
View article: Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC
Therapeutic efficacy of TMTP1-modified EVs in overcoming bone metastasis and immune resistance in PIK3CA mutant NSCLC Open
View article: Study on the correlation between insomnia degree and quality of life in psychiatric outpatients in Chifeng city
Study on the correlation between insomnia degree and quality of life in psychiatric outpatients in Chifeng city Open
BACKGROUND Insomnia is a common sleep disorder that negatively impacts quality of life and is frequently comorbid with depression and anxiety. Chronic insomnia affects approximately 15% of the global population, with higher prevalence amon…
View article: Causal effect of gut microbiota on the risk of cancer and potential mediation by inflammatory proteins
Causal effect of gut microbiota on the risk of cancer and potential mediation by inflammatory proteins Open
View article: MonoBox: Tightness-Free Box-Supervised Polyp Segmentation Using Monotonicity Constraint
MonoBox: Tightness-Free Box-Supervised Polyp Segmentation Using Monotonicity Constraint Open
We propose MonoBox, an innovative box-supervised segmentation method constrained by monotonicity to liberate its training from the user-unfriendly box-tightness assumption. In contrast to conventional box-supervised segmentation, where the…
View article: Clinical Characteristics of <scp>SARS</scp>‐<scp>COV</scp>‐2 Omicron Variant in Acute Myeloid Leukemia and Acute Lymphocytic Leukemia Patients: A Multi‐Center Retrospective Study
Clinical Characteristics of <span>SARS</span>‐<span>COV</span>‐2 Omicron Variant in Acute Myeloid Leukemia and Acute Lymphocytic Leukemia Patients: A Multi‐Center Retrospective Study Open
Background The death rate of hematological malignancies is high, and the death rate of patients with COVID‐19 infection is further increased. Although there have been expert consensus and relevant guidelines to introduce the recommendation…
View article: Porosity prediction based on improved structural modeling deep learning method guided by petrophysical information
Porosity prediction based on improved structural modeling deep learning method guided by petrophysical information Open
View article: Safety and Complications of Ventriculoatrial Shunting in Elderly Patients: A Single-Center Retrospective Study
Safety and Complications of Ventriculoatrial Shunting in Elderly Patients: A Single-Center Retrospective Study Open
The observed complication rate of VA shunting in elderly patients was no higher compared with that of other age groups or other cerebrospinal fluid shunting techniques, reported in previous studies.