Explanipedia

Comparison of supine and sitting pulmonary pressures in ambulatory heart failure patients using the novel Cordella pulmonary pressure system Open

Husam M. Salah, Tamás Alexy, Ryan J. Tedford, Nicholas Hiivala, Max M. Owens , et al. · 2025

Aims The aim of this study is to examine the relationship between supine and seated pulmonary artery pressure (PAP) measurements using the CordellaTM HF management system (Cordella) in patients with heart failure (HF). Method and results P…

Responsiveness validity for measures of adjustment to life with a left ventricular assist device: Findings from the MCS A-QOL study Open

Elizabeth A. Hahn, Larry A. Allen, David Cella, David G. Beiser, Quin E. Denfeld , et al. · 2025

ClinicalTrials.gov ID: NCT03044535.

Association of Kidney Function With Incident Heart Failure: An Analysis of the Women's Health Initiative Open

Richard K. Cheng, Mary B. Roberts, Nisha Bansal, Kerryn W. Reding, Taufiq Salahuddin , et al. · 2025

Background Studies have shown an association of chronic kidney disease with heart failure (HF); however, this association has not been adequately examined in postmenopausal women, who are at heightened risk of both chronic kidney disease a…

Changes in Seated Pulmonary Artery Pressure in Response to Titration of Heart Failure Medications During Ambulatory Monitoring Open

Sandip Zalawadiya, Michael S. Kiernan, Barry A. Borlaug, Lynne W. Stevenson, Akshay S. Desai , et al. · 2025

The AHM platform using seated mPAP data provided valuable insights into its short-term responses to isolated changes in HF medications. The seated mPAP changed expectedly in response to the titration of LD, whereas the degree of response v…

Seated Pulmonary Artery Pressure Monitoring in Patients With Heart Failure Open

Jason L. Guichard, Eric L. Bonno, Michael E. Nassif, Taiyeb Khumri, David Miranda , et al. · 2024

Remote management of seated mPAP is safe and results in a low rate of HF hospitalizations and mortality. These results support the use of seated mPAP monitoring and extend the growing body of evidence that pulmonary artery pressure-guided …

Heart failure related cardiogenic shock: An ISHLT consensus conference content summary Open

Manreet Kanwar, Filio Billia, Varinder K. Randhawa, Jennifer Cowger, Christopher M. Barnett , et al. · 2023

Safety and Performance of the Aortix Device in Acute Decompensated Heart Failure and Cardiorenal Syndrome Open

Jennifer Cowger, Mir B. Basir, David A. Baran, Chris Hayward, Janani Rangaswami , et al. · 2023

This pilot study of patients with ADHF, persistent congestion, and worsening renal function due to CRS supports the potential for safely achieving decongestion using IAEP therapy. These initial promising results provide the basis for futur…

Corrigendum to “HFSA Expert Consensus Statement on the Medical Management of Patients on Durable Mechanical Circulatory Support” Open

Barry Trachtenberg, Douglas L. Jennings, Gillian Grafton, Renzo Y. Loyaga‐Rendon, Rebecca Cogswell , et al. · 2023

PROMIS: Physical, Mental and Social Health Outcomes Improve From Before to Early After LVAD Implant: Findings From the Mechanical Circulatory Support: Measures of Adjustment and Quality of Life (MCS A-QOL) Study Open

Elizabeth A. Hahn, Larry A. Allen, Christopher S. Lee, Quin E. Denfeld, Josef Stehlik , et al. · 2023

Validity of Patient-Reported Outcomes Measurement Information System Physical, Mental, and Social Health Measures After Left Ventricular Assist Device Implantation and Implications for Patient Care Open

Elizabeth A. Hahn, Mary Norine Walsh, Larry A. Allen, Christopher S. Lee, Quin E. Denfeld , et al. · 2023

Background: A better understanding is needed of the burdens and benefits of left ventricular assist device (LVAD) implantation on patients’ physical, mental, and social well-being. The purpose of this report was to evaluate the validity of…

Electrocardiogram Detection of Pulmonary Hypertension Using Deep Learning Open

Mandar A. Aras, Sean Abreau, Hunter Mills, Lakshmi Radhakrishnan, Liviu Klein , et al. · 2023

Evaluation and Treatment of Central Sleep Apnea in Patients with Heart Failure Open

Marat Fudim, Izza Shahid, Sitaramesh Emani, Liviu Klein, Kara Dupuy-McCauley , et al. · 2022

Sleep-disordered breathing (SDB) is a common comorbidity in patients with heart failure (HF). Prevalence of the most common subtypes of SDB, central sleep apnea (CSA) and obstructive sleep apnea (OSA), is increasing, which is concerning du…

Endovascular ablation of the right greater splanchnic nerve in heart failure with preserved ejection fraction: early results of the <span>REBALANCE‐HF</span> trial roll‐in cohort Open

Marat Fudim, Peter Fail, Sheldon E. Litwin, Tamaz Shaburishvili, Parag Goyal , et al. · 2022

Aims In heart failure (HF) with preserved ejection fraction (HFpEF), excessive redistribution of blood volume into the central circulation leads to elevations of intracardiac pressures with exercise limitations. Splanchnic ablation for vol…

Improving clinical trial efficiency using a machine learning‐based risk score to enrich study populations Open

Karola Jering, C. Campagnari, Brian Claggett, Eric Adler, Liviu Klein , et al. · 2022

Aims Prognostic enrichment strategies can make trials more efficient, although potentially at the cost of diminishing external validity. Whether using a risk score to identify a population at increased mortality risk could improve trial ef…

Global best practices consensus: Long-term management of patients with hybrid centrifugal flow left ventricular assist device support Open

Chris Hayward, Iki Adachi, Sylvie Baudart, Erin Davis, Erika Feller , et al. · 2022

With decreasing worldwide experience in the ongoing management of HVAD-supported patients, this consensus guideline provides a summary of best practice techniques from international centers. Differences in HeartMate 3 management are highli…

Multiple cArdiac seNsors for mAnaGEment of Heart Failure (MANAGE-HF) – Phase I Evaluation of the Integration and Safety of the HeartLogic Multisensor Algorithm in Patients With Heart Failure Open

Adrian F. Hernandez, Nancy M. Albert, Larry A. Allen, Rezwan Ahmed, Viktoria Averina , et al. · 2022

ClinicalTrials.gov (NCT03237858).

Clinically Important Differences Are Useful for Interpreting Patient-Reported Outcomes Measurement Information System (PROMIS) Measures After Left Ventricular Assist Device (LVAD) Implantation: Findings from the Mechanical Circulatory Support: Measures of Adjustment and Quality of Life (MCS A-QOL) Study Open

ElizabethA. Hahn, Mary Norine Walsh, David G. Beiser, L. Allen, Colleen K. McIlvennan , et al. · 2022

Novel Noninvasive Biosensors and Artificial Intelligence for Optimized Heart Failure Management Open

Luke A Neill, Mozziyar Etemadi, Liviu Klein, Omer T. Inan · 2022

Is There a Logic in Using Device-Based Algorithms to Prevent Heart Failure Decompensations? Open

Liviu Klein · 2021

Long-Term Electrocardiographic and Echocardiographic Progression of Arrhythmogenic Right Ventricular Cardiomyopathy and Their Correlation With Ventricular Tachyarrhythmias Open

Shadi Kalantarian, Meriam Åström Aneq, Jana Svetlichnaya, Shikha Sharma, Eric Vittinghoff , et al. · 2021

Background: Prior studies of structural and electrocardiographic changes in arrhythmogenic right ventricular (RV) cardiomyopathy and their role in predicting ventricular arrhythmias (ventricular tachycardia) have shown conflicting results.…

Predicting Incident Heart Failure in Women With Machine Learning: The Women’s Health Initiative Cohort Open

Geoffrey H. Tison, Robert Avram, Gregory Nah, Liviu Klein, Barbara V. Howard , et al. · 2021

Use of Ballistocardiography to Monitor Cardiovascular Hemodynamics in Preeclampsia Open

Odayme Quesada, Md Mobashir Hasan Shandhi, Shire Beach, Sean Dowling, Damini Tandon , et al. · 2021

Objective: Pregnancy requires a complex physiological adaptation of the maternal cardiovascular system, which is disrupted in women with pregnancies complicated by preeclampsia, putting them at higher risk of future cardiovas…

Two-Year Follow Up of the LATERAL Clinical Trial Open

Georg Wieselthaler, Liviu Klein, Anson Cheung, Matthew Danter, M. Strueber , et al. · 2021

Background: The LATERAL trial validated the safety and efficacy of the thoracotomy approach for implantation of the HeartWare HVAD System, leading to Food and Drug Administration approval. We sought to analyze 24-month adverse event (AE) r…

Association of Sedentary Time and Incident Heart Failure Hospitalization in Postmenopausal Women Open

Michael J. LaMonte, Joseph C. Larson, JoAnn E. Manson, John Bellettiere, Cora E. Lewis , et al. · 2020

Background: The 2018 US Physical Activity Guidelines recommend reducing sedentary behavior (SB) for cardiovascular health. SB’s role in heart failure (HF) is unclear. Methods: We studied 80 982 women in the Women’s Health Initiative Observ…

When the At-Risk Do Not Develop Heart Failure: Understanding Positive Deviance Among Postmenopausal African American and Hispanic Women Open

Khadijah Breathett, Lindsay N. Kohler, Charles B. Eaton, Nora Franceschini, Lorena García , et al. · 2020

Temporal Associations and Outcomes of Breast Cancer and Heart Failure in Postmenopausal Women Open

Phillip H. Lam, Ana Barac, Anju Nohria, Kerryn W. Reding, Samer S. Najjar , et al. · 2020

Wearable Patch-Based Estimation of Oxygen Uptake and Assessment of Clinical Status during Cardiopulmonary Exercise Testing in Patients With Heart Failure Open

Md Mobashir Hasan Shandhi, Sinan Hersek, Joanna Fan, Erica Sander, Teresa De Marco , et al. · 2020

Improving risk prediction in heart failure using machine learning Open

Eric Adler, Adriaan A. Voors, Liviu Klein, Fima Macheret, Oscar Ö. Braun , et al. · 2019

Background Predicting mortality is important in patients with heart failure (HF). However, current strategies for predicting risk are only modestly successful, likely because they are derived from statistical analysis methods that fail to …

Classification of Decompensated Heart Failure From Clinical and Home Ballistocardiography Open

Varol Burak Aydemir, Supriya Nagesh, Md Mobashir Hasan Shandhi, Joanna Fan, Liviu Klein , et al. · 2019

In future work, a clinician/caregiver can be introduced into the system so that appropriate interventions can be performed based on the clinical state monitored at home.

Pregnancy complications and premature cardiovascular events among 1.6 million California pregnancies Open

Rima Arnaout, Gregory Nah, Gregory M. Marcus, Zian H. Tseng, Elyse Foster , et al. · 2019

Background Cardiovascular complications of pregnancy present an opportunity to assess risk for subsequent cardiovascular disease. We sought to determine whether peripartum cardiomyopathy and hypertensive disorder of pregnancy subtypes pred…

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