Liya He
YOU?
Author Swipe
View article: A new prognostic model for lung adenocarcinoma according propionate metabolism related genes: a comprehensive bioinformatic study
A new prognostic model for lung adenocarcinoma according propionate metabolism related genes: a comprehensive bioinformatic study Open
Background The prognostic mechanisms of lung adenocarcinoma (LUAD) remain unclear, while the propionate metabolic pathway has been implicated in promoting tumor growth across multiple cancer types. This study aims to elucidate the mechanis…
View article: Proteomic analysis of peripheral blood hematopoietic stem cells in children with acquired non-severe aplasia anemia
Proteomic analysis of peripheral blood hematopoietic stem cells in children with acquired non-severe aplasia anemia Open
Objective Acquired aplastic anemia is a bone marrow failure disease caused by various factors, particularly immune disorders. In order to understand the the pathogenesis of non-severe aplastic anemia (NSAA), we employed label-free proteomi…
View article: Molecular Epidemiological Characteristics, Antifungal Resistance and Pathogenicity of Candida auris in Guangzhou, South China
Molecular Epidemiological Characteristics, Antifungal Resistance and Pathogenicity of Candida auris in Guangzhou, South China Open
Background Candida auris represents a global health threat with increasing incidence in China, yet the molecular epidemiology and virulence traits of this pathogen remain poorly characterized. Methods This study comprehensively analyzed 39…
View article: Neuroendocrine carcinoma of the bladder: do they have a worse prognosis? A large retrospective cohort study by propensity score matching analysis
Neuroendocrine carcinoma of the bladder: do they have a worse prognosis? A large retrospective cohort study by propensity score matching analysis Open
Background: The aim was to develop nomograms by integrating clinical characteristics and treatment data to predict overall survival (OS) and cancer-specific survival (CSS) for bladder patients including urothelial carcinoma (UC) and neuroe…
View article: Application prospects of ferroptosis in colorectal cancer
Application prospects of ferroptosis in colorectal cancer Open
Colorectal cancer (CRC) is a serious threat to human health with the third morbidity and the second cancer-related mortality worldwide. It is urgent to explore more effective strategy for CRC because of the acquired treatment resistance fr…
View article: Trend Analysis and Cross Nations Inequality Analysis of Infectious Skin Diseases from 1990 to 2021
Trend Analysis and Cross Nations Inequality Analysis of Infectious Skin Diseases from 1990 to 2021 Open
Background The skin serves as a crucial barrier against microbial invasion, but breaches in this barrier can lead to infectious skin diseases (ISD). ISD, including bacterial (BSD), fungal (FSD) and viral Skin Disease (VSD), pose significan…
View article: Variant spectrum of F8 and F9 in hemophilia patients from southern China and 26 novel variants
Variant spectrum of F8 and F9 in hemophilia patients from southern China and 26 novel variants Open
Hemophilia, an X-linked recessive disorder, is characterized by spontaneous or trauma-induced prolonged bleeding. It is classified as hemophilia A when caused by variants in the F8 gene, and hemophilia B when caused by F9 variants. Few stu…
View article: Inflammatory cutaneous metastases originating from gastric cancer: A case report
Inflammatory cutaneous metastases originating from gastric cancer: A case report Open
BACKGROUND Cutaneous metastasis with gastric cancer (GC) origin is extremely rare and associated with poor prognosis. Nodular type is the most common type, while other forms are extremely rare. CASE SUMMARY This study describes severe skin…
View article: Synchronous double primary tumors of liver (small cell neuroendocrine carcinoma and hepatocellular carcinoma)：A case report
Synchronous double primary tumors of liver (small cell neuroendocrine carcinoma and hepatocellular carcinoma)：A case report Open
This study presents a case of dual primary liver cancer involving small cell neuroendocrine carcinoma and hepatocellular carcinoma. The patient, a 58-year-old Chinese male with a medical history of viral hepatitis B, presented with right u…
View article: Case report: A case of incontinentia pigmenti
Case report: A case of incontinentia pigmenti Open
Incontinentia pigmenti (IP) is a rare neuroectodermal dysplasia caused by mutations in the IKBKG gene. We present a case of a 4-month-old female infant with erythematous vesicular skin lesions on the trunk and extremities. Histopathologic …
View article: Epithelioid hemangioendothelioma of the retroperitoneal giant type treated with Toripalimab: A case report
Epithelioid hemangioendothelioma of the retroperitoneal giant type treated with Toripalimab: A case report Open
Epithelioid hemangioendotheliomas (EHEs), low-grade malignant tumors of vascular endothelial cell origin, are characterized by vascular endothelial proliferation. In 2002, the World Health Organization classified EHEs as locally aggressive…
View article: Cardiac metastasis from small cell lung cancer origin: A case report and review of the literature
Cardiac metastasis from small cell lung cancer origin: A case report and review of the literature Open
Background Cardiac metastasis from small cell lung cancer (SCLC) origin is rare, whereas the incidence is anticipated to increase with the extended survival rates. Case: We here describe a case report of a 48‐year‐old male patient diagnosi…
View article: ELISA based assays to measure adenosine deaminases concentration in serum and saliva for the diagnosis of ADA2 deficiency and cancer
ELISA based assays to measure adenosine deaminases concentration in serum and saliva for the diagnosis of ADA2 deficiency and cancer Open
Adenosine deaminases (ADAs) are enzymes of purine metabolism converting adenosine to inosine. There are two types of ADAs in humans ADA1 and ADA2. While both ADA1 and ADA2 share the same substrate, they differ in expression, cellular local…
View article: Combination therapy (toripalimab and lenvatinib)-associated toxic epidermal necrolysis in a patient with metastatic liver cancer: A case report
Combination therapy (toripalimab and lenvatinib)-associated toxic epidermal necrolysis in a patient with metastatic liver cancer: A case report Open
Cautious attention should be given to rashes that develop after combination therapy with PD-1 inhibitors and lenvatinib. Large-dose and long-course glucocorticoids may be crucial for the treatment of TEN associated with this combination tr…
View article: Progress of Surgery on Platinum-sensitive Recurrent Ovarian Cancer
Progress of Surgery on Platinum-sensitive Recurrent Ovarian Cancer Open
The high incidence and fatality rate of recurrent ovarian cancer (ROC) have always been the clinical problem. For part of patients with platinum-sensitive recurrent ovarian cancer, the secondary cytoreductive surgery (SCS) followed by plat…
View article: Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature
Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone: A case report and review of the literature Open
This case report highlights the importance of cautiously treating life-threatening hyponatremia in patients treated with nedaplatin.
View article: Comparison of clinical features on admission between coronavirus disease 2019 and influenza A among children: a retrospective study in China
Comparison of clinical features on admission between coronavirus disease 2019 and influenza A among children: a retrospective study in China Open
Background: Coronavirus disease 2019 (COVID-19) share similar symptoms with influenza A (IA), but it is more worthwhile to understand the disparities of the two infections regarding their clinical characteristics on admission. Methods: A t…
View article: Comparison of Clinical Features on Admission Between Coronavirus Disease 2019 and Influenza A among Children: A Retrospective Study in China
Comparison of Clinical Features on Admission Between Coronavirus Disease 2019 and Influenza A among Children: A Retrospective Study in China Open
Background: Coronavirus disease 2019 (COVID-19) share similar symptoms with influenza A (IA), but it is more worthwhile to understand the disparities of the two infections regarding their clinical characteristics on admission. Methods: A t…
View article: <i>AcuD</i>Gene Knockout Attenuates the Virulence of<i>Talaromyces marneffei</i>in a Zebrafish Model
<i>AcuD</i>Gene Knockout Attenuates the Virulence of<i>Talaromyces marneffei</i>in a Zebrafish Model Open
Talaromyces marneffei is the only dimorphic species in its genus and causes a fatal systemic mycosis named talaromycosis. Our previous study indicated that knockdown of AcuD gene (encodes isocitrate lyase of glyoxylate bypass) of T. marnef…
View article: Combination of procalcitonin and C‐reactive protein levels in the early diagnosis of bacterial co‐infections in children with H1N1 influenza
Combination of procalcitonin and C‐reactive protein levels in the early diagnosis of bacterial co‐infections in children with H1N1 influenza Open
Objective This study evaluated the diagnostic value of measuring the levels of procalcitonin (PCT) and C‐reactive protein (CRP) to differentiate children co‐infected with H1N1 influenza and bacteria from children infected with H1N1 influen…
View article: Combined use of procalcitonin and C-reactive protein levels can help clinically diagnose bacterial co-infections in children infected with H1N1 influenza
Combined use of procalcitonin and C-reactive protein levels can help clinically diagnose bacterial co-infections in children infected with H1N1 influenza Open
Objective This study evaluated the diagnostic value of measuring the levels of procalcitonin (PCT) and C-reactive protein (CRP) to differentiate children co-infected with H1N1 influenza and bacteria from children infected with H1N1 influen…