Liyang Hu
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View article: An efficient approach with theoretical guarantees to simultaneously reconstruct activity and attenuation sinogram for TOF-PET
An efficient approach with theoretical guarantees to simultaneously reconstruct activity and attenuation sinogram for TOF-PET Open
In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the estimat…
View article: An investigative meta-analysis on the effectiveness and safety of integrating VEGF/VEGFR inhibitors with PD-1/PD-L1 inhibitors in cases with R/M HNSCC
An investigative meta-analysis on the effectiveness and safety of integrating VEGF/VEGFR inhibitors with PD-1/PD-L1 inhibitors in cases with R/M HNSCC Open
Registered with the International Prospective Register of Systematic Reviews, identifier CRD42023486345.
View article: Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer
Analysis of Related Factors of Venous Thromboembolism in Patients with Ovarian Cancer Open
Objective: To analyze the related factors of venous thromboembolism in patients with ovarian cancer. Methods: A total of 86 patients with ovarian cancer complicated with VTE who were treated in a hospital from January 2021 to…
View article: Construction of Risk Prediction Model for Lower Extremity Deep Vein Thrombosis in Patients with Decompensated Cirrhosis
Construction of Risk Prediction Model for Lower Extremity Deep Vein Thrombosis in Patients with Decompensated Cirrhosis Open
Objective: To develop a prediction model for the risk of lower extremity deep venous thrombosis (DVT) in patients with decompensated liver cirrhosis. Methods: A retrospective study was conducted on 236 inpatients with decompe…
View article: A Parameter-free Nonconvex Low-rank Tensor Completion Model for Spatiotemporal Traffic Data Recovery
A Parameter-free Nonconvex Low-rank Tensor Completion Model for Spatiotemporal Traffic Data Recovery Open
Traffic data chronically suffer from missing and corruption, leading to accuracy and utility reduction in subsequent Intelligent Transportation System (ITS) applications. Noticing the inherent low-rank property of traffic data, numerous st…
View article: Clinical observation of pulmonary lymphoepithelioma-like carcinoma
Clinical observation of pulmonary lymphoepithelioma-like carcinoma Open
Pulmonary LELC usually occurs in non-smoking patients and is associated with EBV infection. Common treatments for tumors include multimodal therapy. The expression of PD-1 may be related to the prognosis of LELC, but more studies are neede…
View article: Transcription factor CDX2 up-regulates proto-oncogenic miR-744 via a promoter activation mechanism in non-small-cell lung cancer
Transcription factor CDX2 up-regulates proto-oncogenic miR-744 via a promoter activation mechanism in non-small-cell lung cancer Open
In summary, our results confirmed for the first time the regulatory mechanism of CDX2 on miR-744 transcription and provided a potential mechanism for CDX2 as an oncogene in lung cancer.
View article: Treatment Patterns and Survival of Patients With Advanced Non-Small Cell Lung Cancer Guided by Comprehensive Genomic Profiling: Real-World Single-Institute Study in China
Treatment Patterns and Survival of Patients With Advanced Non-Small Cell Lung Cancer Guided by Comprehensive Genomic Profiling: Real-World Single-Institute Study in China Open
Although the National Comprehensive Cancer Network and the Chinese Society of Clinical Oncology guidelines recommend comprehensive genomic profiling of lung adenocarcinoma, it has not been widely applied in Chinese hospitals. This observat…
View article: Transcription Factor CDX2 Upregulates Proto-oncogenic miR-744 via Promoter Activation Mechanism in Non-small-cell Lung Cancer
Transcription Factor CDX2 Upregulates Proto-oncogenic miR-744 via Promoter Activation Mechanism in Non-small-cell Lung Cancer Open
Background: The role of caudal-related Homeobox 2 (CDX2) in the pathogenesis of non-small cell lung cancer (NSCLC) is unclear. The purpose of this study was to investigate the mRNA expression CDX2 in NSCLC, and to determine its relationshi…
View article: Factors for peripherally inserted central catheters care delay in cancer patients during the COVID-19 pandemic
Factors for peripherally inserted central catheters care delay in cancer patients during the COVID-19 pandemic Open
Physical aspects, social factors, and psychological status commonly influenced patients' health care seeking behaviors such as PICCs maintenance. An increase in effort is required from patients' families and society to assure optimal care …
View article: Clinical observation of Pemetrexed first-line treatment in advanced non-squamous lung cancer or non-small cell lung cancer without driver-mutations: a phase 2, single-arm trial
Clinical observation of Pemetrexed first-line treatment in advanced non-squamous lung cancer or non-small cell lung cancer without driver-mutations: a phase 2, single-arm trial Open
This study is the first to investigate the survival benefit and toxicity tolerance of pemetrexed treatment in non-dominant population in the real world, providing a new therapeutic possibility for those who failed to be enrolled in clinica…
View article: The impact of the COVID-19 pandemic on lung cancer patients
The impact of the COVID-19 pandemic on lung cancer patients Open
This is the first study investigating impact of COVID-19 on non-COVID-19 lung cancer patients during the pandemic. The study demonstrates the significant impact of the COVID-19 crisis on oncological care, indicating the need for appropriat…
View article: Diagnostic value of circulating microRNAs for liver cirrhosis: a meta-analysis
Diagnostic value of circulating microRNAs for liver cirrhosis: a meta-analysis Open
Circulating microRNAs are potential biomarkers for various diseases including liver cirrhosis. We designed a meta-analysis to evaluate the diagnostic value of circulating microRNAs for liver cirrhosis patients. Eligible studies were identi…
View article: Expression and clinical value of programmed cell death-ligand 1 (PD-L1) in diffuse large B cell lymphoma: a retrospective study
Expression and clinical value of programmed cell death-ligand 1 (PD-L1) in diffuse large B cell lymphoma: a retrospective study Open
View article: Transient Elastography (FibroScan) Performs Better Than Non-Invasive Markers in Assessing Liver Fibrosis and Cirrhosis in Autoimmune Hepatitis Patients
Transient Elastography (FibroScan) Performs Better Than Non-Invasive Markers in Assessing Liver Fibrosis and Cirrhosis in Autoimmune Hepatitis Patients Open
BACKGROUND Autoimmune hepatitis (AIH) is an immune-mediated chronic liver disease that can lead to severe fibrosis and cirrhosis. Transient elastography (TE, FibroScan) can assess the fibrotic stages of chronic liver diseases by liver stif…
View article: The Effect of Prophylactic Lamivudine plus Adefovir Therapy Compared with Lamivudine Alone in Preventing Hepatitis B Reactivation in Lymphoma Patients with High Baseline HBV DNA during Chemotherapy
The Effect of Prophylactic Lamivudine plus Adefovir Therapy Compared with Lamivudine Alone in Preventing Hepatitis B Reactivation in Lymphoma Patients with High Baseline HBV DNA during Chemotherapy Open
Prophylactic antiviral therapy is essential for lymphoma patients with high baseline HBV DNA who undergo cytotoxic chemotherapy. However, there are limited data on the optimal options. The present study was designed to compare the efficacy…