Li Zhao
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View article: Lypd6b depletion promotes CD8+ T cell-mediated anti-tumor immunity via metabolic reprogramming in colorectal cancer
Lypd6b depletion promotes CD8+ T cell-mediated anti-tumor immunity via metabolic reprogramming in colorectal cancer Open
View article: Suppression of cavity mode noise in off-axis ICOS based on a Kalman filter optimized by NRBO-SVMD and LSTM
Suppression of cavity mode noise in off-axis ICOS based on a Kalman filter optimized by NRBO-SVMD and LSTM Open
Residual cavity mode noise represents a major constraint on the detection accuracy of trace gases in off-axis Integrated cavity output spectroscopy (OA-ICOS). The Kalman filter (KF) is employed for the noise suppression owing to its strong…
View article: Effects of Aerobic Exercises at Different Intensities on Sleep Quality in Individuals with Depression: A Systematic Review and Meta-Analysis
Effects of Aerobic Exercises at Different Intensities on Sleep Quality in Individuals with Depression: A Systematic Review and Meta-Analysis Open
www.crd.york.ac.uk/PROSPERO/, identifier, CRD42023455212.
View article: Application of low molecular weight heparin on immunoglobulin (IG) A，IgG , IgM, prothrombin time (PT), thrombin time (TT), fibrinogen (FIB), and activated partial thrombokinase time (APTT) , tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleuk
Application of low molecular weight heparin on immunoglobulin (IG) A，IgG , IgM, prothrombin time (PT), thrombin time (TT), fibrinogen (FIB), and activated partial thrombokinase time (APTT) , tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleuk Open
Objective: To explore the impact of low molecular weight heparin (LMWH) on serum immunoglobulin (IG) A，IgG , IgM, prothrombin time (PT), thrombin time (TT), fibrinogen (FIB), and activated partial thrombokinase time (APTT) , tumor necrosis…
View article: Synchronous double primary hepatocellular carcinoma and intrahepatic cholangiocarcinoma in a single patient with chronic hepatitis B: two case reports and literature review
Synchronous double primary hepatocellular carcinoma and intrahepatic cholangiocarcinoma in a single patient with chronic hepatitis B: two case reports and literature review Open
Simultaneous occurrence of primary hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) is rare. We report two cases of synchronous double primary HCC and ICC (sdpHCC-ICC), both associated with chronic hepatitis B. Case…
View article: A Meta-Analysis of the Efficacy of Exercise versus Cognitive Behavioral Therapy in the Treatment of Adults with Binge Eating Disorder
A Meta-Analysis of the Efficacy of Exercise versus Cognitive Behavioral Therapy in the Treatment of Adults with Binge Eating Disorder Open
This meta-analysis evaluates the efficacy of exercise vs. Cognitive Behavioral Therapy (CBT) in Binge Eating Disorder (BED), focusing on: binge eating frequency; Binge Eating Scale (BES); body composition (Body Mass Index, BMI); depressive…
View article: Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection
Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection Open
This study investigated the role of the nuclear factor of activated T cells c3 (NFATc3) in vascular smooth muscle cells (VSMCs) during aortic aneurysm and dissection (AAD) progression and the underlying molecular mechanisms. Cytoplasmic an…
View article: The Role of Glutamatergic Neurons in Changes of Synaptic Plasticity Induced by THz Waves
The Role of Glutamatergic Neurons in Changes of Synaptic Plasticity Induced by THz Waves Open
Background: Terahertz (THz) waves, lying between millimeter waves and infrared light, may interact with biomolecules due to their unique energy characteristics. However, whether THz waves are neurally regulated remains controversial, and t…
View article: THz Waves Improve Spatial Working Memory by Increasing the Activity of Glutamatergic Neurons in Mice
THz Waves Improve Spatial Working Memory by Increasing the Activity of Glutamatergic Neurons in Mice Open
Terahertz (THz) waves, a novel type of radiation with quantum and electronic properties, have attracted increasing attention for their effects on the nervous system. Spatial working memory, a critical component of higher cognitive function…
View article: L-Lactate Administration Improved Synaptic Plasticity and Cognition in Early 3xTg-AD Mice
L-Lactate Administration Improved Synaptic Plasticity and Cognition in Early 3xTg-AD Mice Open
Synaptic plasticity impairment and behavioral deficits constitute classical pathological hallmarks in early-stage Alzheimer’s disease (AD). Emerging evidence suggests these synaptic dysfunctions may stem from metabolic dysregulation, parti…
View article: The systematic analysis of genes related to butyrate metabolism suggests that CDKN3 could serve as a promising therapeutic target for lung adenocarcinoma treatment
The systematic analysis of genes related to butyrate metabolism suggests that CDKN3 could serve as a promising therapeutic target for lung adenocarcinoma treatment Open
We identify and validate a novel BMR-related prognostic signature comprising 5 DEGs for LUAD patients. Our data might provide a new molecular target for LUAD treatment.
View article: Compound exposure of 2.8 GHz and 9.3 GHz microwave causes learning and memory impairment in rats
Compound exposure of 2.8 GHz and 9.3 GHz microwave causes learning and memory impairment in rats Open
The anxieties and concerns about health hazards caused by microwave has been growing recently. Previous studies have reported microwave induced structural and functional injuries to brain. However, the biological effects caused by compound…
View article: Related Applications of Deep Learning Algorithms in Medical Image Fusion Systems
Related Applications of Deep Learning Algorithms in Medical Image Fusion Systems Open
View article: Screening and identification of vascular endothelial cell targeting peptide in gastric cancer through novel integrated in vitro and in vivo strategy
Screening and identification of vascular endothelial cell targeting peptide in gastric cancer through novel integrated in vitro and in vivo strategy Open
View article: Inactivation of β-coronavirus MHV-A59 by 2.8 GHz microwave
Inactivation of β-coronavirus MHV-A59 by 2.8 GHz microwave Open
From the severe acute respiratory syndrome coronavirus in 2003 to the severe acute respiratory syndrome coronavirus 2 in 2019, coronavirus has seriously threatened human health. Electromagnetic waves not only own high penetration and low p…
View article: Curcumin attenuates microglia-mediated chronic neuropathic pain through CDK5 /p35 signaling pathway
Curcumin attenuates microglia-mediated chronic neuropathic pain through CDK5 /p35 signaling pathway Open
Curcumin is a phenolic compound derived from turmeric, one of the main ingredients of curry powder, which is widely used for its antioxidant, anti-inflammatory and immunomodulatory effects. Curcumin has been reported to help relieve pain, …
View article: Preparation and anti-colon cancer effect of a novel curcumin analogue (CA8): in vivo and in vitro evaluation
Preparation and anti-colon cancer effect of a novel curcumin analogue (CA8): in vivo and in vitro evaluation Open
Chemotherapy remains the first choice of treatment for colon cancer despite the inevitable adverse effects. Curcumin (CU) possesses antitumor activity but has poor aqueous solubility, low bioavailability, and weak activity. To address this…
View article: Author Correction: High-intensity interval training vs. yoga in improving binge eating and physical fitness in inactive young females
Author Correction: High-intensity interval training vs. yoga in improving binge eating and physical fitness in inactive young females Open
View article: Blueberry anthocyanins regulate SIRT1/FoxO1 pathway to inhibit oxidative stress and reduce testicular tissue damage induced by microwave radiation in rats
Blueberry anthocyanins regulate SIRT1/FoxO1 pathway to inhibit oxidative stress and reduce testicular tissue damage induced by microwave radiation in rats Open
Researches have shown that microwave radiation could cause oxidative stress injury in male reproductive system, and blueberry anthocyanins had excellent oxidation resistance. Our study aimed to investigate the protective effect of blueberr…
View article: High-intensity interval training vs. yoga in improving binge eating and physical fitness in inactive young females
High-intensity interval training vs. yoga in improving binge eating and physical fitness in inactive young females Open
Yoga is effective in binge eating disorder (BED) treatment, but it does not seem effective enough to improve low physical fitness. In contrast, high-intensity interval training (HIIT) is effective in improving physical fitness but has neve…
View article: Inactivation efficacy and mechanism of 9.375 GHz electromagnetic wave on coronavirus
Inactivation efficacy and mechanism of 9.375 GHz electromagnetic wave on coronavirus Open
Epidemics caused by pathogenic viruses are a severe threat to public health worldwide. Electromagnetic waves are a type of noncontact and nonionizing radiation technology that has emerged as an effective tool for inactivating bacterial pat…
View article: Pan-Genome Analysis of TRM Gene Family and Their Expression Pattern under Abiotic and Biotic Stresses in Cucumber
Pan-Genome Analysis of TRM Gene Family and Their Expression Pattern under Abiotic and Biotic Stresses in Cucumber Open
Cucumber (Cucumis sativus L.) is a vital economic vegetable crop, and TRM (TONNEAU1 Recruiting Motif) gene plays a key role in cucumber organ growth. However, the pan-genomic characteristics of the TRM gene family and their expression patt…
View article: Microwave Radiation Caused Dynamic Metabolic Fluctuations in the Mammalian Hippocampus
Microwave Radiation Caused Dynamic Metabolic Fluctuations in the Mammalian Hippocampus Open
To investigate the dynamic changes in hippocampal metabolism after microwave radiation using liquid chromatography in tandem with mass spectrometry/mass spectrometry (LC–MS/MS) and to identify potential biomarkers. Wistar rats were randoml…
View article: Mechanism of Microwave Radiation-Induced Learning and Memory Impairment Based on Hippocampal Metabolomics
Mechanism of Microwave Radiation-Induced Learning and Memory Impairment Based on Hippocampal Metabolomics Open
The brain is complex and metabolically active, and the detection of metabolites plays an important role in brain development and diseases. Currently, there is a lack of research on the metabolic spectrum changes in learning and memory impa…
View article: The Structural Basis of Learning and Memory Impairment Induced by Compound Exposure of 2.8 Ghz and 9.3 Ghz Microwave on Rats
The Structural Basis of Learning and Memory Impairment Induced by Compound Exposure of 2.8 Ghz and 9.3 Ghz Microwave on Rats Open
View article: A Malware Detection Method Based on Genetic Algorithm Optimized CNN-SENet Network
A Malware Detection Method Based on Genetic Algorithm Optimized CNN-SENet Network Open
In recent years, convolutional neural network (CNN) has achieved great success in the field of network security protection. With the popularization of smart terminals and the gradual increase of power grid informatization and digitization,…
View article: Feasibility of the Anchor‐Free Deep Learning Method in Coronary Stenosis Automatic Detection
Feasibility of the Anchor‐Free Deep Learning Method in Coronary Stenosis Automatic Detection Open
Background . Coronary artery disease (CAD) is a type of cardiovascular disease which is one of the leading causes of death around the world. The presence of coronary stenosis is considered a pivotal indicator in the diagnosis of various CA…
View article: Tanshinone IIA Alleviates Early Brain Injury after Subarachnoid Hemorrhage in Rats by Inhibiting the Activation of NF-κB/NLRP3 Inflammasome
Tanshinone IIA Alleviates Early Brain Injury after Subarachnoid Hemorrhage in Rats by Inhibiting the Activation of NF-κB/NLRP3 Inflammasome Open
The abnormal activation of the nuclear factor-kappa B (NF-κB)/nod-like receptor family-pyrin domain-containing 3 (NLRP3) signaling pathway is closely related to early brain injury after subarachnoid hemorrhage (SAH). Targeting the NLRP3-in…
View article: Treadmill exercise prevents the hyperexcitability of pyramidal neurons in medial entorhinal cortex in the 3xTg-AD mouse model of Alzheimer's disease
Treadmill exercise prevents the hyperexcitability of pyramidal neurons in medial entorhinal cortex in the 3xTg-AD mouse model of Alzheimer's disease Open
Neuronal hyperactivity is a key abnormality in early stage Alzheimer's disease (AD). Medial entorhinal cortex (mEC) plays a vital role in memory function and is affected early in AD. Growing evidence indicates benefits of regular exercise …
View article: Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice
Aerobic exercise attenuates abnormal myelination and oligodendrocyte differentiation in 3xTg-AD mice Open
Pathological features of Alzheimer's Disease (AD) include alterations in the structure and function of neurons as well as of myelin sheaths. Accumulated evidence shows that aerobic type of exercise can enhance neuroplasticity in mouse mode…