Lizhi Jiang
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View article: Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis
Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis Open
The vertebrate retina serves as a model for studying neurogenesis and cell fate specification, with retinal progenitor cells following a tightly regulated temporal sequence to generate distinct cell types. Meis1 and Meis2 are transcription…
View article: Long-term variability of extreme precipitation with WRF model at a complex terrain River Basin
Long-term variability of extreme precipitation with WRF model at a complex terrain River Basin Open
Global warming has profound effects on precipitation patterns, leading to more frequent and extreme precipitation events over the world. These changes pose significant challenges to the sustainable development of socio-economic and ecologi…
View article: Investigating the Microphysical Characteristics and Environmental Influences of Warm-Rain Precipitation in Fuzhou Region
Investigating the Microphysical Characteristics and Environmental Influences of Warm-Rain Precipitation in Fuzhou Region Open
View article: Investigating the Microphysical Characteristics and Environmental Influences of Warm-Rain Precipitation in Fuzhou Region
Investigating the Microphysical Characteristics and Environmental Influences of Warm-Rain Precipitation in Fuzhou Region Open
View article: Design, Synthesis and Antiproliferation Evaluation of Salvianolic Acid A Derivatives and Regulation Activity of the Expression of HER2
Design, Synthesis and Antiproliferation Evaluation of Salvianolic Acid A Derivatives and Regulation Activity of the Expression of HER2 Open
View article: Simplified Maxwell-Boltzmann-Hansch Function (SMBH function) and its Application in PROTAC
Simplified Maxwell-Boltzmann-Hansch Function (SMBH function) and its Application in PROTAC Open
View article: High affinity and low PARP-trapping benzimidazole derivatives as a potential warhead for PARP1 degraders
High affinity and low PARP-trapping benzimidazole derivatives as a potential warhead for PARP1 degraders Open
View article: Increasing risks of the explosive extratropical cyclones over the North Atlantic storm track: a perspective from their surface wind maxima
Increasing risks of the explosive extratropical cyclones over the North Atlantic storm track: a perspective from their surface wind maxima Open
Extratropical cyclones play a crucial role in balancing the global momentum, energy, and moisture, and also, they shape the extreme weather events over the extra-tropics. As the strongest category of the extratropical cyclones, the explosi…
View article: High Affinity and Low PARP-Trapping Benzimidazole Derivatives as a Potential Warhead for PARP1 Degraders
High Affinity and Low PARP-Trapping Benzimidazole Derivatives as a Potential Warhead for PARP1 Degraders Open
View article: Analysis of the fine-mesh subgroup method and its feasible improvement
Analysis of the fine-mesh subgroup method and its feasible improvement Open
The fine-mesh subgroup method (FSM) is proposed to treat the significant resonance self-shielding effect both effectively and accurately. Similar to the ultra-fine group method, the fine-mesh subgroup method adopts a fine group structure o…
View article: Sensitivity of WRF multiple parameterization schemes to extreme precipitation event over the Poyang Lake Basin of China
Sensitivity of WRF multiple parameterization schemes to extreme precipitation event over the Poyang Lake Basin of China Open
Global warming leads to more frequent and more violent extreme weather events, which cause severe natural disasters. The sensitivity of physical schemes in numerical weather prediction models for extreme precipitation is a significant chal…
View article: Cell-specific regulation of gene expression using splicing-dependent frameshifting
Cell-specific regulation of gene expression using splicing-dependent frameshifting Open
Precise and reliable cell-specific gene delivery remains technically challenging. Here we report a splicing-based approach for controlling gene expression whereby separate translational reading frames are coupled to the inclusion or exclus…
View article: Spatial and temporal heterogeneity of tropical cyclone precipitation over China from 1959 to 2018
Spatial and temporal heterogeneity of tropical cyclone precipitation over China from 1959 to 2018 Open
Tropical cyclone precipitation (TCP) can cause serious floods and urban waterlogs as well as cause various secondary disasters, such as landslides and debris flows, which negatively affect human lives and the sustainable development of the…
View article: Projection of future climate change in the Poyang Lake Basin of China under the global warming of 1.5–3°C
Projection of future climate change in the Poyang Lake Basin of China under the global warming of 1.5–3°C Open
This study projected the future climate changes in the Poyang Lake Basin (PLB) of China under various global warming targets (1.5–3°C), based on the latest Coupled Model Intercomparison Project Phase 6 (CMIP6) and 4 statistical downscaling…
View article: How Well Does the ERA5 Reanalysis Capture the Extreme Climate Events Over China? Part II: Extreme Temperature
How Well Does the ERA5 Reanalysis Capture the Extreme Climate Events Over China? Part II: Extreme Temperature Open
The fifth-generation atmospheric reanalysis of the European Center for Medium-Range Weather Forecasts (ERA5) is the latest reanalysis product. However, the reliability of ERA5 to capture extreme temperatures is still unclear over China. He…
View article: How Well Does the ERA5 Reanalysis Capture the Extreme Climate Events Over China? Part I: Extreme Precipitation
How Well Does the ERA5 Reanalysis Capture the Extreme Climate Events Over China? Part I: Extreme Precipitation Open
ERA5 is the fifth-generation atmospheric reanalysis of the European Center for Medium-Range Weather Forecasts, with high spatiotemporal resolution and global coverage. However, the reliability of ERA5 for simulating extreme precipitation e…
View article: Cell-specific regulation of gene expression using splicing-dependent frameshifting.
Cell-specific regulation of gene expression using splicing-dependent frameshifting. Open
Precise cell-specific gene delivery remains technically challenging. Here we report a splicing-based approach whereby separate translational reading frames are coupled to the inclusion or exclusion of cell-specific alternative exons. Candi…
View article: Cell-specific regulation of gene expression using splicing-dependent frameshifting
Cell-specific regulation of gene expression using splicing-dependent frameshifting Open
Precise and reliable cell-specific gene delivery remains technically challenging. Here we report a splicing-based approach for controlling gene expression whereby separate translational reading frames are coupled to the inclusion or exclus…
View article: Author Correction: The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development
Author Correction: The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development Open
View article: Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina
Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina Open
View article: Gene regulatory networks controlling temporal patterning, neurogenesis, and cell fate specification in the mammalian retina
Gene regulatory networks controlling temporal patterning, neurogenesis, and cell fate specification in the mammalian retina Open
Gene regulatory networks (GRNs), consisting of transcription factors and their target cis- regulatory sequences, control neurogenesis and cell fate specification in the developing central nervous system, but their organization is poorly ch…
View article: The impact of ectopic expression of the Kruppel-like Factors on mammalian retinal development
The impact of ectopic expression of the Kruppel-like Factors on mammalian retinal development Open
View article: Control of neurogenic competence in mammalian hypothalamic tanycytes
Control of neurogenic competence in mammalian hypothalamic tanycytes Open
Loss of function of NFI transcription factors in hypothalamic tanycytes generates diverse subtypes of functional neurons.
View article: On the vertical extending of the explosive extratropical cyclone: A case study
On the vertical extending of the explosive extratropical cyclone: A case study Open
Explosive extratropical cyclone (EEC) is the main disastrous weather system over the ocean and offshore areas in the cold season. As a type of vertically deep system, after decades of studies, key features of EECs' vertical extents still r…
View article: Gene Regulatory Networks Controlling Temporal Patterning, Neurogenesis, and Cell Fate Specification in the Mammalian Retina
Gene Regulatory Networks Controlling Temporal Patterning, Neurogenesis, and Cell Fate Specification in the Mammalian Retina Open
View article: A new mesoscale-vortex identification metric: restricted vorticity and its application
A new mesoscale-vortex identification metric: restricted vorticity and its application Open
Mesoscale vortices (MVs) play an important role in balancing global atmospheric momentum, moisture, and energy, and can induce almost all types of disastrous weather. To enhance the understanding of MVs, there is a need to identify them fr…
View article: Control of neurogenic competence in mammalian hypothalamic tanycytes
Control of neurogenic competence in mammalian hypothalamic tanycytes Open
Hypothalamic tanycytes, radial glial cells that share many features with neuronal progenitors, generate small numbers of neurons in the postnatal hypothalamus, but the identity of these neurons and the molecular mechanisms that control tan…
View article: Gene regulatory networks controlling vertebrate retinal regeneration
Gene regulatory networks controlling vertebrate retinal regeneration Open
Unlocking retinal regeneration in mice Zebrafish can regenerate damaged retinal tissue, but mice cannot. Hoang et al. found that tracking changes in gene expression and chromatin accessibility upon injury revealed clues as to why retinal g…
View article: The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development
The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development Open
View article: New method for detecting extratropical cyclones: the eight-section slope detecting method
New method for detecting extratropical cyclones: the eight-section slope detecting method Open