Lizhu Zhang
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View article: Exploring System 1 and 2 communication for latent reasoning in LLMs
Exploring System 1 and 2 communication for latent reasoning in LLMs Open
Should LLM reasoning live in a separate module, or within a single model's forward pass and representational space? We study dual-architecture latent reasoning, where a fluent Base exchanges latent messages with a Coprocessor, and test two…
View article: RecoWorld: Building Simulated Environments for Agentic Recommender Systems
RecoWorld: Building Simulated Environments for Agentic Recommender Systems Open
We present RecoWorld, a blueprint for building simulated environments tailored to agentic recommender systems. Such environments give agents a proper training space where they can learn from errors without impacting real users. RecoWorld d…
View article: GEM: Empowering LLM for both Embedding Generation and Language Understanding
GEM: Empowering LLM for both Embedding Generation and Language Understanding Open
Large decoder-only language models (LLMs) have achieved remarkable success in generation and reasoning tasks, where they generate text responses given instructions. However, many applications, e.g., retrieval augmented generation (RAG), st…
View article: Correlating Solvation Shell Dynamics and Ion Transport in Highly Ordered Nanoporous Polymers
Correlating Solvation Shell Dynamics and Ion Transport in Highly Ordered Nanoporous Polymers Open
A molecular-level understanding of the role of hydration in ion transport is essential for developing the next generation of polymeric anion exchange membranes (AEMs). Structural heterogeneity of conventional membranes, complex ion-water a…
View article: Correlating Solvation Shell Dynamics and Ion Transport in Highly Ordered Nanoporous Polymers
Correlating Solvation Shell Dynamics and Ion Transport in Highly Ordered Nanoporous Polymers Open
A molecular-level understanding of the role of hydration in ion transport is essential for developing the next generation of polymeric anion exchange membranes (AEMs). Structural heterogeneity of conventional membranes, complex ion-water a…
View article: Beyond Reward Hacking: Causal Rewards for Large Language Model Alignment
Beyond Reward Hacking: Causal Rewards for Large Language Model Alignment Open
Recent advances in large language models (LLMs) have demonstrated significant progress in performing complex tasks. While Reinforcement Learning from Human Feedback (RLHF) has been effective in aligning LLMs with human preferences, it is s…
View article: Surface Hydrophobicity Governs Collision Dynamics of Emulsion Droplets on Bare and Sams-Modified Electrodes
Surface Hydrophobicity Governs Collision Dynamics of Emulsion Droplets on Bare and Sams-Modified Electrodes Open
View article: Impact of land-use change on coupling coordination degree of regional water–food–carbon system
Impact of land-use change on coupling coordination degree of regional water–food–carbon system Open
Introduction The objective of this study is to investigate the impact of land use changes on the coupling coordination of the regional water-food-carbon system in Hebei Province. Moreover, the findings aim to offer insights for achieving c…
View article: The development and validation of a prognostic prediction modeling study in acute myocardial infarction patients after percutaneous coronary intervention: hemorrhea and major cardiovascular adverse events
The development and validation of a prognostic prediction modeling study in acute myocardial infarction patients after percutaneous coronary intervention: hemorrhea and major cardiovascular adverse events Open
The XGBoost model (machine learning) performed better than the traditional logistic regression model in identifying hemorrhea and MACE after PCI. Machine learning models can be used as a tool for risk prediction. The machine learning model…
View article: Photosensitized Reductive Elimination of Gold(III) to Enable Esterification of Aryl Iodides with Carboxylic Acids
Photosensitized Reductive Elimination of Gold(III) to Enable Esterification of Aryl Iodides with Carboxylic Acids Open
Compared to the well-established transition metal-catalyzed cross-coupling reactions, Au(I)/Au(III)-catalyzed cross-coupling reactions have lagged behind. Despite some advancements, achieving gold-catalyzed C-O coupling with carboxylic aci…
View article: Spatial and temporal evolution of the eco-efficiency of cultivated land use in the region around Beijing–Tianjin based on the Super-EBM model
Spatial and temporal evolution of the eco-efficiency of cultivated land use in the region around Beijing–Tianjin based on the Super-EBM model Open
The eco-efficiency of cultivated land use (ECLU) is an important indicator for ecological civilization construction in China. Exploring the spatiotemporal dynamic evolution of the ECLU is helpful for the sustainable use of arable land, ens…
View article: Base-assisted transmetalation enables gold-catalyzed oxidative Sonogashira coupling reaction
Base-assisted transmetalation enables gold-catalyzed oxidative Sonogashira coupling reaction Open
The traditional transition metal catalyzed neutral C(sp)-C(sp2) cross-coupling reaction between a nucleophile and an electrophile is a key technique for the formation of carbon-carbon bonds. Herein, we present a general gold-cat…
View article: Spatial and Temporal Evolution of the Eco-Efficiency of Cultivated Land Use in the Region around Beijing-Tianjin Based on the Super-EBM Model
Spatial and Temporal Evolution of the Eco-Efficiency of Cultivated Land Use in the Region around Beijing-Tianjin Based on the Super-EBM Model Open
The eco-efficiency of cultivated land use (ECLU) is an important indicator for the construction of ecological civilization in China. Exploring the spatiotemporal dynamic evolution of the ECLU is helpful for sustainable use of arable land, …
View article: Hetero‐Anionic Structure Activated CoS Bonds Promote Oxygen Electrocatalytic Activity for High‐Efficiency Zinc–Air Batteries (Adv. Mater. 36/2023)
Hetero‐Anionic Structure Activated CoS Bonds Promote Oxygen Electrocatalytic Activity for High‐Efficiency Zinc–Air Batteries (Adv. Mater. 36/2023) Open
Oxygen Electrocatalysis To investigate the bifunctional performance of heterogeneous anionic structures for oxygen electrocatalysis, CuCo2O4−xSx/NC-2 catalysts, which exhibit excellent catalytic performance for the oxygen evolution/reducti…
View article: Recent advances of natural pigments from algae
Recent advances of natural pigments from algae Open
View article: Alcohol consumption promotes arsenic absorption but reduces tissue arsenic accumulation in mice
Alcohol consumption promotes arsenic absorption but reduces tissue arsenic accumulation in mice Open
Alcohol consumption alters gut microflora and damages intestinal tight junction barriers, which may affect arsenic (As) oral bioavailability. In this study, mice were exposed to arsenate in the diet (6 μg/g) over a 3-week period and gavage…
View article: Nutritional assessment models for Alzheimer's disease: Advances and perspectives
Nutritional assessment models for Alzheimer's disease: Advances and perspectives Open
Alzheimer's disease (AD) is a neurodegenerative disease of uncertain pathogenesis that develops in the elderly population and is characterized by loss of cognitive function, memory loss, and deterioration of everyday behavior. The developm…
View article: Base-Assisted Transmetalation Enables Gold-Catalyzed Oxidative Sonogashira Coupling Reaction
Base-Assisted Transmetalation Enables Gold-Catalyzed Oxidative Sonogashira Coupling Reaction Open
View article: Ruthenium-Catalyzed Β-Alkylation of Secondary Alcohols with Primary Alcohols: Protic N-Heterocyclic Carbene's Promotional Influence
Ruthenium-Catalyzed Β-Alkylation of Secondary Alcohols with Primary Alcohols: Protic N-Heterocyclic Carbene's Promotional Influence Open
View article: Emerging applications of metabolomics in food science and future trends
Emerging applications of metabolomics in food science and future trends Open
View article: Correction: Global seaweed farming and processing in the past 20 years
Correction: Global seaweed farming and processing in the past 20 years Open
View article: CCDC 949802: Experimental Crystal Structure Determination
CCDC 949802: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Global seaweed farming and processing in the past 20 years
Global seaweed farming and processing in the past 20 years Open
Seaweed has emerged as one of the most promising resources due to its remarkable adaptability, short development period, and resource sustainability. It is an effective breakthrough to alleviate future resource crises. Algal resources have…
View article: Polypyrrole/Schiff Base Composite as Electromagnetic Absorbing Material with High and Tunable Absorption Performance
Polypyrrole/Schiff Base Composite as Electromagnetic Absorbing Material with High and Tunable Absorption Performance Open
In recent years, Schiff base-related conjugated systems have received extensive attention, but little research has been done in the field of electromagnetic materials. In this work, an organic conjugated system based on polypyrrole/hydrazo…
View article: Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway
Baicalin protects against renal interstitial fibrosis in mice by inhibiting the TGF-β/Smad signalling pathway Open
These findings support the use of baicalin as a potential therapeutic option for the treatment of RIF by possibly inhibiting the TGF-β/Smad signalling pathway.
View article: Comparison of ticagrelor and clopidogrel in the treatment of patients with coronary heart disease carrying CYP2C19 loss of function allele
Comparison of ticagrelor and clopidogrel in the treatment of patients with coronary heart disease carrying CYP2C19 loss of function allele Open
CYP2C19 polymorphism was associated with the prognosis of patients with CHD administered antiplatelet therapy with oral clopidogrel. The incidence of poor prognosis was significantly increased with CYP2C19*2 and/or CYP2C19…
View article: Cover Feature: Electrochemical Synthesis of Trisubstituted Oxazoles and Imines from β‐Diketones and Amines (ChemElectroChem 15/2022)
Cover Feature: Electrochemical Synthesis of Trisubstituted Oxazoles and Imines from β‐Diketones and Amines (ChemElectroChem 15/2022) Open
The Cover Feature shows electrochemical synthesis of trisubstituted oxazoles from β-diketones and amines, like the high energy meet-up between a Chinese dragon and a tiger typically described in Chinese folklore. More information can be fo…
View article: Detection and imaging of Hg(II) in vivo using glutathione-functionalized gold nanoparticles
Detection and imaging of Hg(II) in vivo using glutathione-functionalized gold nanoparticles Open
The optical and biological properties of functionalized gold nanoparticles (GNPs) have been widely used in sensing applications. GNPs have a strong binding ability to thiol groups. Furthermore, thiols are used to bind functional molecules,…
View article: A switch-based biosensor for the detection and imaging of Hg(II) in vivo by glutathione functionalized gold nanoparticles
A switch-based biosensor for the detection and imaging of Hg(II) in vivo by glutathione functionalized gold nanoparticles Open
The optical and biological properties of the tunable functionalized gold nanoparticles (GNPs) tuned have been widely used in the sensing applications. GNPs have a strong binding ability to sulfhydryl groups of thiols. Furthermore, thiols i…
View article: Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1
Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1 Open
In cervical cancer (CC), cisplatin resistance greatly restricts the application in clinical. Here, we report that engineered exosomes-mediated transfer of hsa-miR-320a overcomes chemoresistance in cervical cancer cells via targeting Myeloi…