Linlin Wang
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View article: Integrative clinical and molecular characterization of an acute promyelocytic leukemia-like subgroup with high early death risk in newly diagnosed acute myeloid leukemia: a multicenter study
Integrative clinical and molecular characterization of an acute promyelocytic leukemia-like subgroup with high early death risk in newly diagnosed acute myeloid leukemia: a multicenter study Open
Not available.
View article: Efficacy and Safety of Remote Ischemic Conditioning for Depression Insufficiently Responsive to Antidepressant: A Randomized Controlled Trial
Efficacy and Safety of Remote Ischemic Conditioning for Depression Insufficiently Responsive to Antidepressant: A Randomized Controlled Trial Open
For depression patients with poor response to antidepressant therapy, the efficacy of RIPC as adjuvant therapy was not observed in this study. In general, RIPC adjuvant therapy is relatively safe, and has no significant effect on cardiovas…
View article: Evaluating the bioaccessibility of yak milk lipids in infants: Dynamic gastrointestinal simulation reveals lipidomic alterations
Evaluating the bioaccessibility of yak milk lipids in infants: Dynamic gastrointestinal simulation reveals lipidomic alterations Open
Yak milk is considered an excellent dairy source for infant formula, owing to its lipid advantages including superior fatty acid composition, abundant short- and medium-chain fatty acids, and higher phospholipid content. This study compare…
View article: Recent progress on electrodeposition of metal/alloy films or coatings in deep eutectic solvents
Recent progress on electrodeposition of metal/alloy films or coatings in deep eutectic solvents Open
View article: Correlation of air pollution and risk of sudden sensorineural hearing loss: a Mendelian randomization study
Correlation of air pollution and risk of sudden sensorineural hearing loss: a Mendelian randomization study Open
Numerous compelling epidemiological studies have linked air pollution to Sudden Sensorineural Hearing Loss (SSNHL). However, the causal relationship behind this association has not yet been established. We employed a Two-Sample Mendelian R…
View article: Albumin-to-Globulin ratio as an independent risk factor for predicting prognostic risk in patients with acute coronary syndrome undergoing percutaneous coronary intervention
Albumin-to-Globulin ratio as an independent risk factor for predicting prognostic risk in patients with acute coronary syndrome undergoing percutaneous coronary intervention Open
AGR < 1.350 is an independent prognostic risk factor for patients with ACS undergoing PCI and may be a valuable clinical marker for identifying high-risk patients.
View article: Incidence and risk factors of pneumonitis in ALK-rearranged non-small cell lung cancer patients treated with alectinib and thoracic radiotherapy
Incidence and risk factors of pneumonitis in ALK-rearranged non-small cell lung cancer patients treated with alectinib and thoracic radiotherapy Open
The combined use of alectinib and TRT significantly increased the risk of TRP. Clinicians should consider the elevated risks and related dosimetric factors when deciding on combination treatment for ALK-rearranged NSCLC patients.
View article: Associations between organophosphate flame retardants and risk for nonsyndromic cleft lip and/or palate in offspring
Associations between organophosphate flame retardants and risk for nonsyndromic cleft lip and/or palate in offspring Open
Introduction Nonsyndromic cleft lip and/or palate (NSCL/P) is a common congenital malformation with a complex etiology involving many environmental factors. Organophosphate flame retardants (OPFRs) are a class of emerging contaminants that…
View article: Interaction between Maslinic acid and HSF1 enhances the ubiquitin degradation of HSF1, resulting in the inhibitory effect of pancreatic cancer
Interaction between Maslinic acid and HSF1 enhances the ubiquitin degradation of HSF1, resulting in the inhibitory effect of pancreatic cancer Open
View article: Corrigendum to “Association between alkali and alkaline earth elements in chorionic villus and risk for spontaneous abortion” [Ecotoxicol. Environ. Saf. 290 (2025)117516]
Corrigendum to “Association between alkali and alkaline earth elements in chorionic villus and risk for spontaneous abortion” [Ecotoxicol. Environ. Saf. 290 (2025)117516] Open
View article: Albumin-to-Globulin ratio as an independent risk factor for predicting prognostic risk in patients with acute coronary syndrome undergoing percutaneous coronary intervention
Albumin-to-Globulin ratio as an independent risk factor for predicting prognostic risk in patients with acute coronary syndrome undergoing percutaneous coronary intervention Open
Purpose: Acute coronary syndromes (ACS) is a leading cause of death worldwide. Albumin and globulin are the main components of serum proteins. The albumin-to-globulin ratio (AGR) is often used to assess nutritional status. However, the cli…
View article: Associations of prenatal co-exposure to phthalate metabolites and bisphenols with neural tube defects
Associations of prenatal co-exposure to phthalate metabolites and bisphenols with neural tube defects Open
Introduction Neural tube defects (NTDs) are one of the most common birth defects. Phthalates and bisphenols are ubiquitous endocrine-disrupting chemicals (EDCs), which can disrupt the endocrine system by altering hormone levels. However, t…
View article: Genome-Wide Identification and Evolutionary Analysis of Ionotropic Receptors Gene Family: Insights into Olfaction Ability Evolution and Antennal Expression Patterns in Oratosquilla oratoria
Genome-Wide Identification and Evolutionary Analysis of Ionotropic Receptors Gene Family: Insights into Olfaction Ability Evolution and Antennal Expression Patterns in Oratosquilla oratoria Open
Olfaction plays a crucial role in crustaceans for essential activities such as foraging and predator evasion. Among the components involved in olfactory perception, Ionotropic Receptors (IRs) are particularly important. Oratosquilla orator…
View article: A scalable multi-modal learning fruit detection algorithm for dynamic environments
A scalable multi-modal learning fruit detection algorithm for dynamic environments Open
Introduction To enhance the detection of litchi fruits in natural scenes, address challenges such as dense occlusion and small target identification, this paper proposes a novel multimodal target detection method, denoted as YOLOv5-Litchi.…
View article: Primary pulmonary diffuse large B cell lymphoma presenting with features of organizing pneumonia: a case report
Primary pulmonary diffuse large B cell lymphoma presenting with features of organizing pneumonia: a case report Open
View article: Lipidomic study of yak milk reveals potential biomarkers for the design of infant formulas
Lipidomic study of yak milk reveals potential biomarkers for the design of infant formulas Open
Recent research on yak milk has revealed that it is an alternative to cow milk as another high-quality milk source for infant formula milk powder; however, the differences in the lipid profiles of human and yak milk are not yet clear. In t…
View article: Latent-space adversarial training with post-aware calibration for defending large language models against jailbreak attacks
Latent-space adversarial training with post-aware calibration for defending large language models against jailbreak attacks Open
Ensuring safety alignment is a critical requirement for large language models (LLMs), particularly given increasing deployment in real-world applications. Despite considerable advancements, LLMs remain susceptible to jailbreak attacks, whi…
View article: Latent-Space Adversarial Training with Post-Aware Calibration for Defending Large Language Models Against Jailbreak Attacks
Latent-Space Adversarial Training with Post-Aware Calibration for Defending Large Language Models Against Jailbreak Attacks Open
View article: CyTOF Analysis of Immune Characteristics in cSLE: Belimumab Treatment and Refractory Cases
CyTOF Analysis of Immune Characteristics in cSLE: Belimumab Treatment and Refractory Cases Open
View article: Integrated multi-omics analysis reveal Forsythoside A ameliorates inflammatory bowel disease by regulating macrophage metabolic reprogramming via HIF1A/PDK4 pathway
Integrated multi-omics analysis reveal Forsythoside A ameliorates inflammatory bowel disease by regulating macrophage metabolic reprogramming via HIF1A/PDK4 pathway Open
View article: The Global, Regional, and National Disease Burden of Female Breast Cancer Attributable to High Fasting Plasma Glucose from 1990 to 2021: A Cross-Sectional Study
The Global, Regional, and National Disease Burden of Female Breast Cancer Attributable to High Fasting Plasma Glucose from 1990 to 2021: A Cross-Sectional Study Open
View article: Association between alkali and alkaline earth elements in chorionic villus and risk for spontaneous abortion
Association between alkali and alkaline earth elements in chorionic villus and risk for spontaneous abortion Open
Exposure to specific alkali and alkaline earth elements(AEs/AEEs) has been reported that are linked to an increased risk of spontaneous abortion. However, the direct evidence of exposure in the uterus are absent. Therefore, we collected ch…
View article: 6 A novel IL12Rβ1 and IL12Rβ2 humanized mouse model for preclinical efficacy and toxicity evaluation of human IL-12 analogs
6 A novel IL12Rβ1 and IL12Rβ2 humanized mouse model for preclinical efficacy and toxicity evaluation of human IL-12 analogs Open
View article: Periconceptional polycyclic aromatic hydrocarbon levels in maternal hair and fetal risk for congenital heart defects
Periconceptional polycyclic aromatic hydrocarbon levels in maternal hair and fetal risk for congenital heart defects Open
When examined individually, a high concentration of CHR in periconceptional maternal hair was associated with an increased risk for CHDs. When considering the 11 PAHs together, higher levels of the PAHs mixture were associated with increas…
View article: Targeting Decidual CD16 <sup>+</sup> Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage
Targeting Decidual CD16 <sup>+</sup> Immune Cells with Exosome‐Based Glucocorticoid Nanoparticles for Miscarriage Open
Immune dysfunction in early pregnancy including overactivation of cytotoxic CD16 + NK cells and proinflammatory M1 macrophages at the maternal–fetal interface interferes with trophoblast invasion, spiral artery remodeling, and decidualizat…
View article: An untargeted comparative metabolomics analysis of infants with and without late-onset breast milk jaundice
An untargeted comparative metabolomics analysis of infants with and without late-onset breast milk jaundice Open
Background: Late-onset breast milk jaundice (LBMJ) is a common form of hyperbilirubinemia, which can result in serious complications for newborns with persistently high bilirubin levels. The aim of this study was to investigate the differe…
View article: How Does Digital Inclusive Finance Policy Affect the Carbon Emission Intensity of Industrial Land in the Yangtze River Economic Belt of China? Evidence from Intermediary and Threshold Effects
How Does Digital Inclusive Finance Policy Affect the Carbon Emission Intensity of Industrial Land in the Yangtze River Economic Belt of China? Evidence from Intermediary and Threshold Effects Open
Digital inclusive finance (DIF) is a strategic tool that fosters the green transformation of the industrial economy. Based on the data from the 11 provinces and municipalities in the Yangtze River Economic Belt of China between 2012 and 20…
View article: <i>Bifidobacterium adolescentis</i> CCFM8630 exerts anti-obesity effects by modulating gut microbiota-related tryptophan metabolism
<i>Bifidobacterium adolescentis</i> CCFM8630 exerts anti-obesity effects by modulating gut microbiota-related tryptophan metabolism Open
Obesity is a major focus of researchers due to its increasing prevalence and relationship with other diseases, such as cancer and cardiovascular diseases. Probiotics are active microorganisms and have been proven to alleviate obesity by mo…
View article: Characteristics of Changes in the Intestinal Microbiota of Infants Within 1 Year-Old in Beijing and Its Influencing Factors
Characteristics of Changes in the Intestinal Microbiota of Infants Within 1 Year-Old in Beijing and Its Influencing Factors Open
View article: The causal relationship between 5 serum lipid parameters and diabetic nephropathy: a Mendelian randomization study
The causal relationship between 5 serum lipid parameters and diabetic nephropathy: a Mendelian randomization study Open
Background Serum lipids were found to be correlated with chronic kidney disease and cardiovascular disease. Here, we aimed to research the potential causal associations between five serum lipid parameters and the risk of diabetic nephropat…