Lloyd Sayer
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View article: Label‐Free and Microplate‐Based Dissection of Glycan‐Virus Interactions Using Polymer‐Tethered Glyconanoparticles
Label‐Free and Microplate‐Based Dissection of Glycan‐Virus Interactions Using Polymer‐Tethered Glyconanoparticles Open
Influenza viruses use haemagglutinins (HA) to target host sialic acids in the respiratory tract as do other pathogens, including coronaviruses, which engage using spike protein. The host adaptation of the HA protein, which leads to the acc…
Planar Chiral Pseudo‐Isocoumarins by Copper Catalysed Desymmetrisation Open
A new copper catalysed desymmetrisation reaction of bisalkynyl ferrocenecarboxylic acids using ( R,R )‐Ph‐Pybox results in the first asymmetric synthesis of planar chiral pseudo‐isocoumarins in up to 64 % enantiomeric excess and up to 99 %…
A novel approach towards the stereoselective synthesis of inositols and its application in the synthesis of biologically important molecules Open
Myo-inositol is ubiquitous in nature and is found at the structural core of a diverse range of biologically important derivatives, including phosphatidylinositols, inositol phosphates and mycothiol. The synthesis of myo-inositol derivative…