Ricardo V. Lloyd
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View article: Clinicopathologic and Molecular Characterization of SMARCB1-Deficient Sinonasal Carcinomas – A Systematic Study from a Single Institution Cohort
Clinicopathologic and Molecular Characterization of SMARCB1-Deficient Sinonasal Carcinomas – A Systematic Study from a Single Institution Cohort Open
SMARCB1-deficient carcinomas account for 4.7% of sinonasal carcinomas in this single-institution cohort, while SMARCA4-deficient tumors are even rarer, with none identified. SMARCB1-deficient sinonasal carcinomas exhibit a broad spectrum o…
View article: Seven years of Non-invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP): Rate of Acceptance and Variation of Diagnostic Approaches Across Different Continents
Seven years of Non-invasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (NIFTP): Rate of Acceptance and Variation of Diagnostic Approaches Across Different Continents Open
Context Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) was introduced as a new entity replacing the diagnosis of noninvasive encapsulated follicular variant of papillary thyroid carcinoma (PTC). Signif…
View article: Figure S4 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure S4 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
SERPINE1 expression detected by immunohistochemistry in FTC236-Notch1 xenografts with or without Notch1 induction. (A) and (B). Two representative tumors from the group without Notch1 induction (Dox-); (C) and (D). Two representative tumor…
View article: Supplementary Table S1 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Supplementary Table S1 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Sequences of each primer for real-time quantitative PCR
View article: Material and Methods (supplementary) from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Material and Methods (supplementary) from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Described details of Western blot, clonogenic assay, cell migration assay, ex-vivo imaging, IHC and etc.
View article: Supplementary Table S2 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Supplementary Table S2 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
The top 50 most significant hits from cDNA microarray analysis
View article: Material and Methods (supplementary) from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Material and Methods (supplementary) from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Described details of Western blot, clonogenic assay, cell migration assay, ex-vivo imaging, IHC and etc.
View article: Figure S3 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure S3 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
RFP-positive FTC236-Notch1 cells for the establishment of orthotopic mouse model. (A). Over 26% of the cells from the initial transduced batch were positive for RFP and were sorted for further culturing. (B). The sorted cells were cultured…
View article: Figure S1 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure S1 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
The correlation between age and expression levels of Notch1 in primary DTC samples (A), contra-lateral non-tumor tissues (B) and tissue of benign thyroid disease (C).(A) Scatter plot of negative linear correlation between Notch1 levels and…
View article: Figure legends (supplementary figures) from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure legends (supplementary figures) from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Figure legends for Figure S1-S4
View article: Figure S1 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure S1 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
The correlation between age and expression levels of Notch1 in primary DTC samples (A), contra-lateral non-tumor tissues (B) and tissue of benign thyroid disease (C).(A) Scatter plot of negative linear correlation between Notch1 levels and…
View article: Figure S2 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure S2 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Scratch of a gap for wound healing assay was generated and closure of the gap was evaluated 24 hours later in FTC236-Notch1 cells with or without doxycycline treatment. The cells with NICD induction by doxycycline exhibited slower closure …
View article: Data from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Data from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Purpose: Notch1, a transmembrane receptor, has been recently shown to aid in the determination of thyroid cell fate associated with tumorigenesis. This study aimed to investigate the clinical relevance of Notch1 and its role in the regulat…
View article: Data from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Data from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Purpose: Notch1, a transmembrane receptor, has been recently shown to aid in the determination of thyroid cell fate associated with tumorigenesis. This study aimed to investigate the clinical relevance of Notch1 and its role in the regulat…
View article: Supplementary Table S2 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Supplementary Table S2 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
The top 50 most significant hits from cDNA microarray analysis
View article: Figure S3 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure S3 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
RFP-positive FTC236-Notch1 cells for the establishment of orthotopic mouse model. (A). Over 26% of the cells from the initial transduced batch were positive for RFP and were sorted for further culturing. (B). The sorted cells were cultured…
View article: Supplementary Table S1 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Supplementary Table S1 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Sequences of each primer for real-time quantitative PCR
View article: Figure legends (supplementary figures) from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure legends (supplementary figures) from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Figure legends for Figure S1-S4
View article: Figure S4 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure S4 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
SERPINE1 expression detected by immunohistochemistry in FTC236-Notch1 xenografts with or without Notch1 induction. (A) and (B). Two representative tumors from the group without Notch1 induction (Dox-); (C) and (D). Two representative tumor…
View article: Figure S2 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression
Figure S2 from Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression Open
Scratch of a gap for wound healing assay was generated and closure of the gap was evaluated 24 hours later in FTC236-Notch1 cells with or without doxycycline treatment. The cells with NICD induction by doxycycline exhibited slower closure …
View article: Data from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study
Data from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study Open
For reasons largely unknown, Caucasian women are at a significantly higher risk of developing breast cancer than Asian women. Over a decade ago, mutations in BRCA1/2 were identified as genetic risk factors; however, the discovery of additi…
View article: Supplementary Tables 1-2 from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study
Supplementary Tables 1-2 from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study Open
Supplementary Tables 1-2 from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study
View article: Supplementary Tables 1-2 from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study
Supplementary Tables 1-2 from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study Open
Supplementary Tables 1-2 from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study
View article: Data from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study
Data from Racial Disparity in Breast Cancer and Functional Germ Line Mutation in Galectin-3 (rs4644): A Pilot Study Open
For reasons largely unknown, Caucasian women are at a significantly higher risk of developing breast cancer than Asian women. Over a decade ago, mutations in BRCA1/2 were identified as genetic risk factors; however, the discovery of additi…
View article: Epigenomic and somatic mutations of pituitary tumors with clinical and pathological correlations in 111 patients
Epigenomic and somatic mutations of pituitary tumors with clinical and pathological correlations in 111 patients Open
Objective To profile clinically non‐aggressive and aggressive pituitary adenomas (PAs)/pituitary neuroendocrine tumours (PitNETs) and pituitary carcinomas for somatic mutations and epigenetic alterations of genes involved in cell prolifera…
View article: Cribriform-morular variant of papillary thyroid carcinoma with poorly differentiated features: report of a case and review of the literature
Cribriform-morular variant of papillary thyroid carcinoma with poorly differentiated features: report of a case and review of the literature Open
Introduction Cribrifrom-morular variant of papillary thyroid carcinoma (CMVPTC) is an uncommon thyroid neoplasm that occurs predominantly in women and is sometime associated with familial adenomatous polyposis (FAP). Some of these tumors m…