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View article: #684 Prognostic value of changes in the serum indoxyl sulfate concentration in septic-shock-associated AKI: the Tox-AKI cohort study
#684 Prognostic value of changes in the serum indoxyl sulfate concentration in septic-shock-associated AKI: the Tox-AKI cohort study Open
Background and Aims Indoxyl sulfate (IxS) is a gut-derived toxin that accumulates with kidney function loss and presents endothelial toxicity. Elevated serum concentrations of IxS are associated with adverse outcomes in chronic kidney dise…
View article: Lung recruitment maneuver improves right and left ventricular function in patients with acute respiratory distress syndrome
Lung recruitment maneuver improves right and left ventricular function in patients with acute respiratory distress syndrome Open
View article: Association between arterial oxygen and mortality across critically ill patients with hematologic malignancies: results from an international collaborative network
Association between arterial oxygen and mortality across critically ill patients with hematologic malignancies: results from an international collaborative network Open
View article: Prolonged cardiovascular pharmacological support and fluid management after cardiac surgery
Prolonged cardiovascular pharmacological support and fluid management after cardiac surgery Open
Objective To identify potentially modifiable risk factors related to prolonged cardiovascular pharmacological support after weaning from cardiopulmonary bypass (CPB). Methods This is a secondary analysis of two prospective cohort study in …
View article: Respiratory effects of lung recruitment maneuvers depend on the recruitment-to-inflation ratio in patients with COVID-19-related acute respiratory distress syndrome
Respiratory effects of lung recruitment maneuvers depend on the recruitment-to-inflation ratio in patients with COVID-19-related acute respiratory distress syndrome Open
View article: Non-invasive detection of a femoral-to-radial arterial pressure gradient in intensive care patients with vasoactive agents
Non-invasive detection of a femoral-to-radial arterial pressure gradient in intensive care patients with vasoactive agents Open
View article: Transoesophageal Ultrasound Assessment of Lung Aeration in Patients With Acute Respiratory Distress Syndrome
Transoesophageal Ultrasound Assessment of Lung Aeration in Patients With Acute Respiratory Distress Syndrome Open
Introduction: The effect of positive end-expiratory pressure (PEEP) depends closely on the potential for lung recruitment. Bedside assessment of lung recruitability is crucial for personalized lung-protective mechanical ventilation in acut…
View article: Radial-to-femoral pressure gradient quantification in cardiac surgery
Radial-to-femoral pressure gradient quantification in cardiac surgery Open
View article: Correction to: Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure
Correction to: Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure Open
View article: BMI and pneumonia outcomes in critically ill COVID‐19 patients: An international multicenter study
BMI and pneumonia outcomes in critically ill COVID‐19 patients: An international multicenter study Open
Objective Previous studies have unveiled a relationship between the severity of coronavirus disease 2019 (COVID‐19) pneumonia and obesity. The aims of this multicenter retrospective cohort study were to disentangle the association of BMI a…
View article: Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure
Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure Open
View article: Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure
Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure Open
View article: Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure
Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure Open
Background Delayed intubation is associated with high mortality. There is a lack of objective criteria to decide the time of intubation. We assessed a recently described combined oxygenation index (ROX index) to predict intubation in immun…
View article: Potential risks in using midodrine for persistent hypotension after cardiac surgery: a comparative cohort study
Potential risks in using midodrine for persistent hypotension after cardiac surgery: a comparative cohort study Open
View article: COVID-19– versus non–COVID-19–related Acute Respiratory Distress Syndrome: Differences and Similarities
COVID-19– versus non–COVID-19–related Acute Respiratory Distress Syndrome: Differences and Similarities Open
International audience
View article: Association of Body Mass Index and Other Metabolic Risk Factors with Pneumonia Outcomes in Critically Ill Patients with Coronavirus Disease-19: An International Multicenter Retrospective Cohort Study
Association of Body Mass Index and Other Metabolic Risk Factors with Pneumonia Outcomes in Critically Ill Patients with Coronavirus Disease-19: An International Multicenter Retrospective Cohort Study Open
View article: Center effect in intubation risk in critically ill immunocompromised patients with acute hypoxemic respiratory failure
Center effect in intubation risk in critically ill immunocompromised patients with acute hypoxemic respiratory failure Open
Intubation rates varied considerably among ICUs, even after adjustment on individual characteristics.
View article: Meta-Analysis of Randomized Controlled Trials Using Tool-Assisted Target Weight Adjustments in Chronic Dialysis Patients
Meta-Analysis of Randomized Controlled Trials Using Tool-Assisted Target Weight Adjustments in Chronic Dialysis Patients Open
Among maintenance dialysis recipients, technological adjuncts for fluid management did not improve survival. Trials mostly investigated the use of bioimpedance, whereas the evidence for use of other technologies remain very scarce. Future …
View article: Urinary TIMP2 and IGFBP7 Identifies High Risk Patients of Short-Term Progression from Mild and Moderate to Severe Acute Kidney Injury during Septic Shock: A Prospective Cohort Study
Urinary TIMP2 and IGFBP7 Identifies High Risk Patients of Short-Term Progression from Mild and Moderate to Severe Acute Kidney Injury during Septic Shock: A Prospective Cohort Study Open
Background . To examine whether the new urinary biomarkers TIMP2 and IGFBP7 can predict progression within 24 hours and 72 hours from mild and moderate (KDIGO 1 or 2) to severe (KDIGO 3) AKI in patients with septic shock. Methods . A prosp…
View article: Center effect in intubation risk in critically ill immunocompromised patients with acute hypoxemic respiratory failure
Center effect in intubation risk in critically ill immunocompromised patients with acute hypoxemic respiratory failure Open
Background Acute respiratory failure is the leading reason for intensive care unit (ICU) admission in immunocompromised patients, and the need for invasive mechanical ventilation has become a major clinical endpoint in randomized controlle…
View article: Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With Acute Respiratory Failure
Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With Acute Respiratory Failure Open
clinicaltrials.gov Identifier: NCT02739451.
View article: Oxygenation/non-invasive ventilation strategy and risk for intubation in immunocompromised patients with hypoxemic acute respiratory failure
Oxygenation/non-invasive ventilation strategy and risk for intubation in immunocompromised patients with hypoxemic acute respiratory failure Open
We investigated how the initial ventilation/oxygenation management may influence the need for intubation on the coming day in a cohort of immunocompromised patients with acute hypoxemic respiratory failure (ARF). Data from 847 immunocompro…
View article: High-flow nasal oxygen vs. standard oxygen therapy in immunocompromised patients with acute respiratory failure: study protocol for a randomized controlled trial
High-flow nasal oxygen vs. standard oxygen therapy in immunocompromised patients with acute respiratory failure: study protocol for a randomized controlled trial Open
View article: Neurotoxic Concentration of Piperacillin during Continuous Infusion in Critically Ill Patients
Neurotoxic Concentration of Piperacillin during Continuous Infusion in Critically Ill Patients Open
This retrospective cohort study included 53 patients admitted to the intensive care unit (ICU), with an average age of 69 years, without neurologic disorder before initiation of a continuous piperacillin infusion at the standard dose and w…
View article: Transthoracic echocardiography: an accurate and precise method for estimating cardiac output in the critically ill patient
Transthoracic echocardiography: an accurate and precise method for estimating cardiac output in the critically ill patient Open
View article: Thrombotic Microangiopathy Revealing Bone Metastases from an Ethmoid Sinus Carcinoma
Thrombotic Microangiopathy Revealing Bone Metastases from an Ethmoid Sinus Carcinoma Open
Cancer-related thrombotic microangiopathy (TMA) is a rare entity whose clinical and biological characteristics have been described in various tumors. Here we describe the first case of cancer-related TMA revealing diffuse bone metastases f…
View article: Plasma Exchange in the Management of Catastrophic Antiphospholipid Syndrome
Plasma Exchange in the Management of Catastrophic Antiphospholipid Syndrome Open
Objective . Report of a case of catastrophic antiphospholipid syndrome (CAPS) with multiple organ involvement leading to a life-threatening condition despite early combination corticosteroid and heparin therapy. Initiation of plasma exchan…