Phuoc Loc Doan
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View article: Prospective validation study: a non-invasive circulating tumor DNA-based assay for simultaneous early detection of multiple cancers in asymptomatic adults
Prospective validation study: a non-invasive circulating tumor DNA-based assay for simultaneous early detection of multiple cancers in asymptomatic adults Open
ClinicalTrials.gov ID: NCT05227261. Date of registration: 07/02/2022.
View article: Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks
Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks Open
Background Cell free DNA (cfDNA)-based assays hold great potential in detecting early cancer signals yet determining the tissue-of-origin (TOO) for cancer signals remains a challenging task. Here, we investigated the contribution of a meth…
View article: Analytical and Clinical Validation of a Circulating Tumor DNA-Based Assay for Multi-Cancer Early Detection
Analytical and Clinical Validation of a Circulating Tumor DNA-Based Assay for Multi-Cancer Early Detection Open
View article: Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks
Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks Open
Background Cell free DNA (cfDNA)-based assays hold great potential in detecting early cancer signals yet determining the tissue-of-origin (TOO) for cancer signals remains a challenging task. Here, we investigated the contribution of a meth…
View article: Analytical and clinical validation of a circulating tumor DNA-based assay for multi-cancer early detection
Analytical and clinical validation of a circulating tumor DNA-based assay for multi-cancer early detection Open
Background The emergence of multi-cancer early detection (MCED) via a single blood test offers promise in enhancing the efficiency of early cancer detection and improving population health. However, the lack of analytical validation and cl…
View article: Genetic landscape and personalized tracking of tumor mutations in Vietnamese women with breast cancer
Genetic landscape and personalized tracking of tumor mutations in Vietnamese women with breast cancer Open
Breast cancer is the leading cause of cancer death in Vietnamese women, but its mutational landscape and actionable alterations for targeted therapies remain unknown. After treatment, a sensitive biomarker to complement conventional imagin…