Logan C. Eiler
YOU?
Author Swipe
View article: Evaluation of a Novel Pan-RAS Inhibitor in 3D Bioprinted Tumor Models
Evaluation of a Novel Pan-RAS Inhibitor in 3D Bioprinted Tumor Models Open
Background: Colorectal cancer (CRC) remains a significant global health burden, with KRAS mutations driving ~40% of cases. The efficacy of recently approved, mutant-specific KRAS inhibitors is limited by mutational status as well as intrin…
View article: Potency and selectivity of a novel pan-RAS inhibitor in 3D bioprinted organoid tumor models
Potency and selectivity of a novel pan-RAS inhibitor in 3D bioprinted organoid tumor models Open
Background Colorectal cancer (CRC) remains a significant global health burden, with KRAS mutations driving ∼40% of cases. Efficacy of recently approved, mutant-specific KRAS inhibitors is limited by intrinsic and adaptive resistance mechan…