Logan Keding
YOU?
Author Swipe
View article: A model of sterile placental inflammation: Tisseel-induced thrombotic lesions leads to increased expression of inflammation associated genes in the rhesus macaque placenta 2472
A model of sterile placental inflammation: Tisseel-induced thrombotic lesions leads to increased expression of inflammation associated genes in the rhesus macaque placenta 2472 Open
Description Thrombotic events at the placenta have been associated with pregnancy pathologies, such as preeclampsia (PE) and fetal growth restriction (FGR). Both PE and FGR are characterized by increased placental inflammation. Tisseel, a …
View article: Corrigendum: Deciphering decidual leukocyte traffic with serial intravascular staining
Corrigendum: Deciphering decidual leukocyte traffic with serial intravascular staining Open
[This corrects the article DOI: 10.3389/fimmu.2023.1332943.].
View article: <scp>Cotyledon‐Specific</scp> Flow Evaluation of Rhesus Macaque Placental Injury Using Ferumoxytol Dynamic Contrast‐Enhanced <scp>MRI</scp>
<span>Cotyledon‐Specific</span> Flow Evaluation of Rhesus Macaque Placental Injury Using Ferumoxytol Dynamic Contrast‐Enhanced <span>MRI</span> Open
Background Recently, dynamic contrast‐enhanced (DCE) MRI with ferumoxytol as contrast agent has recently been introduced for the noninvasive assessment of placental structure and function throughout. However, it has not been demonstrated u…
View article: Deciphering decidual leukocyte traffic with serial intravascular staining
Deciphering decidual leukocyte traffic with serial intravascular staining Open
The decidual immunome is dynamic, dramatically changing its composition across gestation. Early pregnancy is dominated by decidual NK cells, with a shift towards T cells later in pregnancy. However, the degree, timing, and subset-specific …
View article: Maternal, placental and fetal response to a non-viral, polymeric nanoparticle gene therapy in nonhuman primates
Maternal, placental and fetal response to a non-viral, polymeric nanoparticle gene therapy in nonhuman primates Open
Background Currently, there are no placenta-targeted treatments to alter the in utero environment. Water-soluble polymers have a distinguished record of clinical relevance outside of pregnancy. We have demonstrated the effective delivery o…
View article: Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an African-lineage Zika virus
Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (Macaca mulatta) with an African-lineage Zika virus Open
Background Congenital Zika virus (ZIKV) infection can result in birth defects, including malformations in the fetal brain and visual system. There are two distinct genetic lineages of ZIKV: African and Asian. Asian-lineage ZIKVs have been …
View article: Fetal Tissues Reflect Decidual-Placental Inflammation
Fetal Tissues Reflect Decidual-Placental Inflammation Open
Maternal inflammation can negatively impact the development of the fetus, leading to long term adverse health outcomes. We previously reported that injection of Tisseel (surgical glue) into the maternal-fetal interface led to necrosis and …
View article: Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (<i>Macaca mulatta</i>) with an African-lineage Zika virus
Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (<i>Macaca mulatta</i>) with an African-lineage Zika virus Open
Background Congenital Zika virus (ZIKV) infection can result in birth defects, including malformations in the fetal brain and visual system. There are two distinct genetic lineages of ZIKV: African and Asian. Asian lineage ZIKVs have been …
View article: Neonatal Development in Prenatally Zika Virus-Exposed Infant Macaques with Dengue Immunity
Neonatal Development in Prenatally Zika Virus-Exposed Infant Macaques with Dengue Immunity Open
Infants exposed to Zika virus (ZIKV) prenatally may develop birth defects, developmental deficits, or remain asymptomatic. It is unclear why some infants are more affected than others, although enhancement of maternal ZIKV infection via im…
View article: Placenta-derived macaque trophoblast stem cells: differentiation to syncytiotrophoblasts and extravillous trophoblasts reveals phenotypic reprogramming
Placenta-derived macaque trophoblast stem cells: differentiation to syncytiotrophoblasts and extravillous trophoblasts reveals phenotypic reprogramming Open
Nonhuman primates are excellent models for studying human placentation as experimental manipulations in vitro can be translated to in vivo pregnancy. Our objective was to develop macaque trophoblast stem cells (TSCs) as an in vitro platfor…
View article: The promise of placental extracellular vesicles: models and challenges for diagnosing placental dysfunction in utero†
The promise of placental extracellular vesicles: models and challenges for diagnosing placental dysfunction in utero† Open
Monitoring the health of a pregnancy is of utmost importance to both the fetus and the mother. The diagnosis of pregnancy complications typically occurs after the manifestation of symptoms, and limited preventative measures or effective tr…
View article: Derivation of macaque trophoblast stem cells
Derivation of macaque trophoblast stem cells Open
Nonhuman primates are excellent models for studying human placentation as experimental manipulations in vitro can be translated to in vivo pregnancy. Our objective was to develop macaque trophoblast stem cells (TSC) as an in vitro platform…
View article: Effects of drug-induced hepatotoxicity on vitellogenesis in the fathead minnow (Pimephales promelas)
Effects of drug-induced hepatotoxicity on vitellogenesis in the fathead minnow (Pimephales promelas) Open
The vitellogenin (VTG) assay is a test used to identify estrogen axis endocrine disruptors (EDs) in fish species. The VTG assay has been seemingly successful, though there are inherent limitations yet to be addressed. Since vitellogenin is…