Logan Massman
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View article: General Anesthetic Exposure in the Management of Pediatric Subglottic Stenosis
General Anesthetic Exposure in the Management of Pediatric Subglottic Stenosis Open
Objectives This study describes time spent under general anesthesia (GA) and number of procedures in children with subglottic stenosis (SGS) treated with endoscopic balloon dilation (EBD), laryngotracheal reconstruction (LTR), or both. Met…
View article: The diverging role of O-GlcNAc Transferase in corticotroph and somatotroph adenomas
The diverging role of O-GlcNAc Transferase in corticotroph and somatotroph adenomas Open
Purpose Molecular mechanisms involved in the pathogenesis and tumor progression of pituitary adenomas (PA) remain incompletely understood. Corticotroph and somatotroph PA associate a high clinical burden, and despite improved surgical outc…
View article: SAT618 Uncovering The Role Of O-glcnacylation In Pituitary Adenoma Pathogenesis: Insights From Corticotroph Tumors
SAT618 Uncovering The Role Of O-glcnacylation In Pituitary Adenoma Pathogenesis: Insights From Corticotroph Tumors Open
Disclosure: L.J. Massman: None. R. Gonzalez: None. B. Laing: None. D. Coss: None. A.G. Ioachimescu: None. N. Zwagerman: None. S. Olivier-Van Stichelen: None. Functioning corticotroph pituitary adenomas are associated with high mortality, m…
View article: <i>O</i> -GlcNAcylation Is Essential for Rapid <i>Pomc</i> Expression and Cell Proliferation in Corticotropic Tumor Cells
<i>O</i> -GlcNAcylation Is Essential for Rapid <i>Pomc</i> Expression and Cell Proliferation in Corticotropic Tumor Cells Open
Pituitary adenomas have a staggering 16.7% lifetime prevalence and can be devastating in many patients because of profound endocrine and neurologic dysfunction. To date, no clear genomic or epigenomic markers correlate with their onset or …
View article: <i>O</i>-GlcNAcylation is essential for rapid <i>Pomc</i> expression and cell proliferation in corticotropic tumor cells
<i>O</i>-GlcNAcylation is essential for rapid <i>Pomc</i> expression and cell proliferation in corticotropic tumor cells Open
Pituitary adenomas have a staggering 16.7% lifetime prevalence and can be devastating in many patients due to profound endocrine and neurologic dysfunction. To date, no clear genomic or epigenomic markers correlates with their onset or sev…
View article: O-GlcNAcylation is essential for rapid Pomc expression and cell proliferation in corticotropic tumor cells (Supplementary Materials, Figures and Tables)
O-GlcNAcylation is essential for rapid Pomc expression and cell proliferation in corticotropic tumor cells (Supplementary Materials, Figures and Tables) Open
Pituitary adenomas have a staggering 16.7% lifetime prevalence and can be devastating in many patients due to profound endocrine and neurologic dysfunction. To date, no clear genomic or epigenomic markers correlates with their onset or sev…
View article: Sex Differences in Adrenal Bmal1 Deletion–Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice
Sex Differences in Adrenal Bmal1 Deletion–Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice Open
The circadian glucocorticoid (GC) rhythm is dependent on a molecular clock in the suprachiasmatic nucleus (SCN) and an adrenal clock that is synchronized by the SCN. To determine whether the adrenal clock modulates GC responses to stress, …
View article: The Adrenal Clock Prevents Aberrant Light-Induced Alterations in Circadian Glucocorticoid Rhythms
The Adrenal Clock Prevents Aberrant Light-Induced Alterations in Circadian Glucocorticoid Rhythms Open
The glucocorticoid (GC) rhythm is entrained to light-dark (LD) cycles via a molecular clock in the suprachiasmatic nucleus (SCN) and is maintained by an adrenal clock synchronized by SCN-dependent signals. Targeted deletion of the core clo…
View article: Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) Are Necessary for Light Entrainment of Peripheral Clocks
Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) Are Necessary for Light Entrainment of Peripheral Clocks Open
Light is a powerful entrainer of circadian clocks in almost all eukaryotic organisms promoting synchronization of internal circadian rhythms with external environmental light-dark (LD) cycles. In mammals, the circadian system is organized …