Loïc Grandvuillemin
YOU?
Author Swipe
View article: Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds
Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds Open
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor belonging to the bHLH/PAS protein family and responding to hundreds of natural and chemical substances. It is primarily involved in the defense against chemical…
View article: Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex
Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex Open
Summary Living organisms have developed protein sensors helping them to adapt to their environment 1 . The aryl hydrocarbon receptor (AHR) is an emblematic member of this class of proteins, and a ligand-dependent transcription factor that …