Longjiang Wu
YOU?
Author Swipe
View article: Disparities in Global Rabies Burden from GBD 2021: Children, older adults, and low-SDI countries at continued risk
Disparities in Global Rabies Burden from GBD 2021: Children, older adults, and low-SDI countries at continued risk Open
Background Rabies is a fatal yet preventable viral infection of the central nervous system zoonotic disease, with an almost 100% case fatality rate once symptoms appear. Despite the availability of effective vaccines and post-exposure prop…
View article: Global Fibrosis Burden and a Transcriptional Biomarker-Based Strategy for Early Detection in Resource-Limited Settings
Global Fibrosis Burden and a Transcriptional Biomarker-Based Strategy for Early Detection in Resource-Limited Settings Open
Fibrotic diseases contribute to nearly half of all deaths in industrialized countries, yet effective early detection strategies remain lacking, particularly in low-resource settings. This study aimed to quantify the global burden of fibros…
View article: Structural insights and milestones in TDP-43 research: A comprehensive review of its pathological and therapeutic advances
Structural insights and milestones in TDP-43 research: A comprehensive review of its pathological and therapeutic advances Open
Transactive response (TAR) DNA-binding protein 43 (TDP-43) is a critical RNA/DNA-binding protein involved in various cellular processes, including RNA splicing, transcription regulation, and RNA stability. Mislocalization and aggregation o…
View article: Green development in the Chengdu-Chongqing economic zone: evolution and drivers from a “production-living-ecology” perspective
Green development in the Chengdu-Chongqing economic zone: evolution and drivers from a “production-living-ecology” perspective Open
Green development is key to promoting regional sustainable development. We construct an evaluation index system for green development levels based on the “sansheng” dimensions—production, living, and ecology. We rely on the “sansheng” (pro…
View article: Development of an ic-CLEIA for precise detection of 3-CQA in herbs and patent medicines: ensuring quality control and therapeutic efficacy
Development of an ic-CLEIA for precise detection of 3-CQA in herbs and patent medicines: ensuring quality control and therapeutic efficacy Open
Background 3-caffeoylquinic acid (3-CQA), a member of the chlorogenic acid family, possesses diverse pharmacological properties, such as scavenging, antioxidant, and antiapoptotic activity, rendering substantial value to alimentary consuma…
View article: Development and evaluation of an immunoassay for the quantification of N-acetylneuraminic acid (Neu5Ac) in foods and biosamples
Development and evaluation of an immunoassay for the quantification of N-acetylneuraminic acid (Neu5Ac) in foods and biosamples Open
N-acetylneuraminic acid is an active ingredient in tonic foods and an important additive in foods and biopharmaceuticals. To address the limitations of existing methods of N-acetylneuraminic acid quantification, we developed an immunoassay…
View article: Analysis of Evolving Carbon Stock Trends and Influencing Factors in Chongqing under Future Scenarios
Analysis of Evolving Carbon Stock Trends and Influencing Factors in Chongqing under Future Scenarios Open
The relationship between land use changes and regional carbon storage is closely linked. Identifying evolving trends concerning and influencing factors on carbon storage under future scenarios is key in order to achieve the “dual carbon” g…
View article: Computational analysis and drug repositioning: Targeting the TDP-43 RRM using FDA-approved drugs
Computational analysis and drug repositioning: Targeting the TDP-43 RRM using FDA-approved drugs Open
TAR DNA binding protein-43 (TDP-43) aggregation is a hallmark for many neurodegenerative diseases including amyotrophic lateral sclerosis, frontotemporal dementia and Huntington’s disease. These protein aggregates can disrupt neuronal func…
View article: MS2 Virus-like Particles as a Versatile Peptide Presentation Platform: Insights into the Deterministic Abilities for Accommodating Heterologous Peptide Lengths
MS2 Virus-like Particles as a Versatile Peptide Presentation Platform: Insights into the Deterministic Abilities for Accommodating Heterologous Peptide Lengths Open
Virus-like particles (VLPs) are nanostructures with the potential to present heterologous peptides at high density, thereby triggering heightened immunogenicity. RNA bacteriophage MS2 VLPs are a compelling delivery platform among them. How…
View article: Antibody mimetics: the next generation antibody engineering, a retrospective and prospective analysis
Antibody mimetics: the next generation antibody engineering, a retrospective and prospective analysis Open
Antibody mimetics is a novel antibody engineering approach after the development of polyclonal, monoclonal antibodies, and genetically engineered antibody fragments. Inspired by the structure and function of natural antibodies, antibody mi…
View article: Antibody mimetics: the next generation antibody engineering, a retrospective and prospective analysis
Antibody mimetics: the next generation antibody engineering, a retrospective and prospective analysis Open
Antibody mimetics is a novel antibody engineering approach after the development of polyclonal, monoclonal antibodies, and genetically engineered antibody fragments. Inspired by the structure and function of natural antibodies, antibody mi…
View article: <i>Apocynum venetum</i>, a medicinal, economical and ecological plant: a review update
<i>Apocynum venetum</i>, a medicinal, economical and ecological plant: a review update Open
Apocynum venetum L. is an important medicinal perennial rhizome plant with good ecological and economic value. Its leaves have many pharmacological effects such as anti-inflammatory, anti-depression, anti-anxiolytic, etc., while its fibers…
View article: Studies on Cistanches Herba: A Bibliometric Analysis
Studies on Cistanches Herba: A Bibliometric Analysis Open
As a famous tonic herb, Cistanches Herba is known for its broad medicinal functions, especially its hormone balancing, anti-aging, anti-dementia, anti-tumor, anti-oxidative, neuroprotective, and hepatoprotective effects. This study aims to…
View article: Impact of Future Development Scenario Selection on Landscape Ecological Risk in the Chengdu-Chongqing Economic Zone
Impact of Future Development Scenario Selection on Landscape Ecological Risk in the Chengdu-Chongqing Economic Zone Open
The management of regional eco-environmental risks is the key to promoting regional economic sustainability from the macro level, and accurate evaluation of the evolutionary trends of regional ecological risk in the future is of high impor…