Longmei Yu
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View article: Global to local burden and inequalty of low respiratory infections among children and adolescents across 953 locations
Global to local burden and inequalty of low respiratory infections among children and adolescents across 953 locations Open
Background Adolescent lower respiratory infections (LRIs) are one of the major public health problems worldwide. Utilizing data from Global Burden of Disease 2021 (GBD 2021), this study aimed to investigate the trends and distribution char…
View article: Combining AlphaFold—based AI docking with omics technologies preliminarily unveils the mechanism of Guominkang in treating allergic rhinitis
Combining AlphaFold—based AI docking with omics technologies preliminarily unveils the mechanism of Guominkang in treating allergic rhinitis Open
Allergic rhinitis (AR) is a common immune-mediated chronic inflammatory disease with a complex pathogenesis involving multiple responses of the immune system and epigenetic changes. In recent years, DNA methylation, a key epigenetic mechan…
View article: Monocytes Expressing <scp>IL</scp>‐<scp>36G</scp> Play a Crucial Role in Atopic Dermatitis
Monocytes Expressing <span>IL</span>‐<span>36G</span> Play a Crucial Role in Atopic Dermatitis Open
Atopic dermatitis ( ad ) is a chronic inflammatory skin disease, with recent studies indicating that immune cells, such as monocytes and inflammatory cytokines, play a crucial role. By retrieving datasets from public databases and analysin…
View article: The diagnostic value of combined detection of microRNA-155, TNF-α and IL-37 for active pulmonary tuberculosis in the elderly.
The diagnostic value of combined detection of microRNA-155, TNF-α and IL-37 for active pulmonary tuberculosis in the elderly. Open
miR-155, TNF-α and IL-37 were overexpressed in elderly patients with active PTB. The combined detection of serum miR-155/TNF-α/IL-37 expression has potential to serve as a diagnostic tool for active PTB in the elderly.
View article: Expression and antibacterial activity of hybrid antimicrobial peptide cecropinA-thanatin in Pichia pastoris
Expression and antibacterial activity of hybrid antimicrobial peptide cecropinA-thanatin in Pichia pastoris Open
The hybrid peptide CA(1–7)-T(4–19) gene was designed according to the N-terminal 1–7 amino acid sequence of the antimicrobial peptide cecropinA (CA) and the N-terminal 4–19 amino acid sequence of thanatin (T), and synthesized by using Pich…