Longqi Sa
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View article: Diagnostic and prognostic significance of tetraspanin 6 and its role in facilitating glioma progression
Diagnostic and prognostic significance of tetraspanin 6 and its role in facilitating glioma progression Open
Our findings emphasize its potential as both a diagnostic and therapeutic target as well as a predictor of immune therapy response in gliomas.
View article: Silencing of SIRPα enhances the antitumor efficacy of CAR-M in solid tumors
Silencing of SIRPα enhances the antitumor efficacy of CAR-M in solid tumors Open
The potential of macrophage-mediated phagocytosis as a cancer treatment is promising. Blocking the CD47–SIRPα interaction with a CD47-specific antibody significantly enhances macrophage phagocytosis. However, concerns regarding their toxic…
View article: DNAJC1 Facilitates Glioblastoma Progression by Promoting Extracellular Matrix Reorganization and Macrophage Infiltration
DNAJC1 Facilitates Glioblastoma Progression by Promoting Extracellular Matrix Reorganization and Macrophage Infiltration Open
Background: Glioblastoma (GBM) is a high-grade and heterogeneous subtype of glioma that presents a substantial challenge to human health, characterized by a poor prognosis and low survival rates. Despite its known involvement in regulating…
View article: M1 polarization enhances the antitumor activity of chimeric antigen receptor macrophages in solid tumors
M1 polarization enhances the antitumor activity of chimeric antigen receptor macrophages in solid tumors Open
Background Chimeric antigen receptor macrophage (CAR-M) therapy is a novel cancer immunotherapy approach that integrates CAR structure and macrophage functions. CAR-M therapy has shown unique and impressive antitumor effects in immunothera…
View article: KDELR2 as a diagnostic and prognostic biomarker of bladder urothelial carcinoma and its correlation with immune infiltration
KDELR2 as a diagnostic and prognostic biomarker of bladder urothelial carcinoma and its correlation with immune infiltration Open
KDELR2 has been reported as a promotive factor for the genesis and progression of several malignancies. However, it is uncertain how it affects bladder urothelial carcinoma (BLCA). Using data extracted from online databases, an enhanced ex…