Longshan Liu
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Author Swipe
View article: Preemptive antibiotic strategies for gram-positive bacteria in preservation fluid: a single-center experience
Preemptive antibiotic strategies for gram-positive bacteria in preservation fluid: a single-center experience Open
Objective To elucidate the risk stratification of gram-positive bacteria in the preservation fluid ( PF ), investigate antibiotic resistance and its role in early post-kidney transplant infections, and assess the efficacy of preemptive-ant…
View article: Left heart function and strain for predicting change in hemoglobin levels in pediatric kidney transplantation recipients
Left heart function and strain for predicting change in hemoglobin levels in pediatric kidney transplantation recipients Open
Introduction Anemia is prevalent after kidney transplantation (KTx) and is associated with reduced graft survival. The associations between temporal changes in hemoglobin (Hb) level in the early posttransplant period with left ventricular …
View article: Consensus on Clinical Application of Normothermic Regional Perfusion in Organ Donation After Circulatory Determination of Death
Consensus on Clinical Application of Normothermic Regional Perfusion in Organ Donation After Circulatory Determination of Death Open
Organ transplantation is the most effective treatment for end‐stage organ disease. One of the major challenges in organ transplantation is organ shortage. For this reason, more and more extended criteria donor organs, including those from …
View article: The effect of low donor-to-recipient body weight ratio on graft survival after dual kidney transplantation from pediatric deceased donors
The effect of low donor-to-recipient body weight ratio on graft survival after dual kidney transplantation from pediatric deceased donors Open
DKT from pediatric donors yields favorable outcomes, with similar graft survival and complication rates across surgical subgroups. However, significant donor-recipient weight mismatch, particularly when the ratio is less than 1:10, may con…
View article: A refined kidney tumor nephrometry system employed to screen pediatric patients who are eligible for nephron sparing surgery
A refined kidney tumor nephrometry system employed to screen pediatric patients who are eligible for nephron sparing surgery Open
Purpose Comprehension of the anatomical characteristics of pediatric kidney tumors is crucial for making surgical decisions. Previous kidney tumor nephrometry systems failed to incorporate two significant factors: tumor thrombus and multif…
View article: The effectiveness of nirmatrelvir/ritonavir regimen in hospitalized renal transplant patients with prolonged COVID-19 infection: a multicenter clinical experience
The effectiveness of nirmatrelvir/ritonavir regimen in hospitalized renal transplant patients with prolonged COVID-19 infection: a multicenter clinical experience Open
A regimen including NR for clearing SARS-CoV-2 along with reducing immunosuppressants and using intravenous corticosteroids is associated with lower rates of exacerbation and mortality in KTRs who have moderate to critical SARS-CoV-2 infec…
View article: Long-term kidney transplant outcomes in Chinese patients with primary glomerulonephritis: A multicenter study in China
Long-term kidney transplant outcomes in Chinese patients with primary glomerulonephritis: A multicenter study in China Open
To the Editor: The primary cause of end-stage kidney disease (ESKD) in China is chronic glomerulonephritis (GN), which accounts for 45% of ESKD patients.[1] There is currently no nationwide large-scale study on the long-term prognosis of k…
View article: Dual‐Targeting Nanovesicles Carrying CSF1/CD47 Identified from Single‐Cell Transcriptomics of Innate Immune Cells in Heart Transplant for Alleviating Acute Rejection (Adv. Healthcare Mater. 7/2024)
Dual‐Targeting Nanovesicles Carrying CSF1/CD47 Identified from Single‐Cell Transcriptomics of Innate Immune Cells in Heart Transplant for Alleviating Acute Rejection (Adv. Healthcare Mater. 7/2024) Open
View article: Value of original and modified pathological scoring systems for prognostic prediction in paraffin-embedded donor kidney core biopsy
Value of original and modified pathological scoring systems for prognostic prediction in paraffin-embedded donor kidney core biopsy Open
No study has validated, compared and adapted scoring systems for prognosis prediction based on donor kidney core biopsy (CB), with less glomeruli than wedge biopsy. A total of 185 donor kidney CB specimens were reviewed using seven scoring…
View article: Prognostic Biomarkers in Kidney Transplantation: A Systematic Review and Critical Appraisal
Prognostic Biomarkers in Kidney Transplantation: A Systematic Review and Critical Appraisal Open
Significance Statement Why are there so few biomarkers accepted by health authorities and implemented in clinical practice, despite the high and growing number of biomaker studies in medical research ? In this meta-epidemiological study, i…
View article: Interferon-gamma FlowSpot assay for the measurement of the T-cell response to cytomegalovirus
Interferon-gamma FlowSpot assay for the measurement of the T-cell response to cytomegalovirus Open
View article: Catch-up growth of children with graft survival after kidney transplantation: A cohort study
Catch-up growth of children with graft survival after kidney transplantation: A cohort study Open
Objective: To describe and explore the clinical characteristics and associated factors of growth in children after kidney transplantation (KT). Method: Retrospective study was performed on the clinical data of 111 children who underwent al…
View article: Incidence, clinical features and risk factors of tacrolimus induced idiosyncratic liver injury in renal transplant recipients: A nested case-control study
Incidence, clinical features and risk factors of tacrolimus induced idiosyncratic liver injury in renal transplant recipients: A nested case-control study Open
Rare data reported tacrolimus-induced liver injury (tac-DILI) in real world. We performed a nested case-control analysis of 1,010 renal transplant recipients. Recipients with tac-DILI were randomly matched at a ratio of 1:4 by the year of …
View article: Abdominal catheter-induced intussusception following renal transplantation in two pediatric recipients: 2 cases report and literature review
Abdominal catheter-induced intussusception following renal transplantation in two pediatric recipients: 2 cases report and literature review Open
Our 2 cases implied that abdominal catheter could be a lead point to induce intussusception, especially in pediatric recipients with abdominal disorder. This experience may be applicable to other surgeries involving indwelling abdominal ca…
View article: Is RENAL Nephrometry Scoring System Suitable for Application in Bilateral Wilms Tumor?
Is RENAL Nephrometry Scoring System Suitable for Application in Bilateral Wilms Tumor? Open
Purpose The RENAL nephrometry scoring system has been validated to predict adult kidney tumor complexity. This study aims to explore the application of RENAL nephrometry scoring system in bilateral Wilms tumor (BWT). Methods A retrospectiv…
View article: Bench surgery with autotransplantation for bilateral Wilms tumor—A feasible technique for renal sinus invasion
Bench surgery with autotransplantation for bilateral Wilms tumor—A feasible technique for renal sinus invasion Open
Purpose Bilateral Wilms tumor (BWT) with renal sinus invasion requires extremely difficult surgical care. This study presents an alternative strategy for tumor removal while at the same time preserving the renal parenchyma. Materials and m…
View article: Changes in myocardial work associated with pediatric kidney transplantation: A pilot study of short‐term postoperative effect
Changes in myocardial work associated with pediatric kidney transplantation: A pilot study of short‐term postoperative effect Open
The study was mainly to evaluate the changes of left ventricular (LV) myocardial work (MW) in children with CKD stage 5 within 3 months after kidney transplantation (KTx). Forty‐three successful KTx recipients (mean age 10.6 years, 58% mal…
View article: Single kidney transplantation from pediatric deceased donors in China: the outcomes and risk factors of graft survival
Single kidney transplantation from pediatric deceased donors in China: the outcomes and risk factors of graft survival Open
SKT from pediatric donors could achieve decent outcomes. Rejection was an independent risk factor of graft survival, especially for adolescent recipients. Child recipients may compromise early transplant outcomes due to vascular thrombosis…
View article: Genotype and phenotype analysis and transplantation strategy in children with kidney failure caused by NPHP
Genotype and phenotype analysis and transplantation strategy in children with kidney failure caused by NPHP Open
Background Nephronophthisis-related ciliopathies (NPHP-RC) have strong genotype and phenotype heterogeneity, and the transplantation strategy of Boichis syndrome is still controversial. Our purpose was to examine associations of genotype a…
View article: COQ8B glomerular nephropathy: Outcomes after kidney transplantation and analysis of characteristics in Chinese population
COQ8B glomerular nephropathy: Outcomes after kidney transplantation and analysis of characteristics in Chinese population Open
Background Mutation in the COQ8B gene can cause COQ8B glomerular nephropathy (COQ8B-GN), which is rare and associated with steroid-resistant nephrotic syndrome (SRNS) as well as rapid progression to end-stage renal disease (ESRD). The aim …
View article: Combining Clinical Parameters and Acute Tubular Injury Grading Is Superior in Predicting the Prognosis of Deceased-Donor Kidney Transplantation: A 7-Year Observational Study
Combining Clinical Parameters and Acute Tubular Injury Grading Is Superior in Predicting the Prognosis of Deceased-Donor Kidney Transplantation: A 7-Year Observational Study Open
Background We developed a pragmatic dichotomous grading criterion to stratify the acute tubular injury (ATI) of deceased-donor kidneys. We intended to verify the predictive value of this criterion for the prognosis of deceased-donor kidney…
View article: Pharmacokinetics of free and total mycophenolic acid in paediatric and adult renal transplant recipients: Exploratory analysis of the effects of clinical factors and gene variants
Pharmacokinetics of free and total mycophenolic acid in paediatric and adult renal transplant recipients: Exploratory analysis of the effects of clinical factors and gene variants Open
Clinical and genetic influencing factors on free fraction of mycophenolic acid (MPA) have rarely been discussed. The present study investigated whether the clinical and genetic factors could explain the variability in the pharmacokinetics …
View article: MicroRNA profile of circulating CD4+ T cells in aged patients with atherosclerosis obliterans
MicroRNA profile of circulating CD4+ T cells in aged patients with atherosclerosis obliterans Open
Background To evaluate the specificity of the expression patterns of microRNAs (miRNAs) in circulating CD4 + T cells in aged patients with atherosclerosis obliterans (ASO). Methods A comprehensive miRNA expression study was conducted using…
View article: Serum Soluble B Cell-Activating Factor Is a Non-Invasive Biomarker of Antibody-Mediated Rejection in Kidney Allograft With Satisfactory Risk Stratification Performance But Negligible Diagnostic Value
Serum Soluble B Cell-Activating Factor Is a Non-Invasive Biomarker of Antibody-Mediated Rejection in Kidney Allograft With Satisfactory Risk Stratification Performance But Negligible Diagnostic Value Open
Objectives B cell-activating factor (BAFF), which is critical in the activation and differentiation of B cells, is a candidate diagnostic and predictive biomarker for antibody-mediated rejection (ABMR). We aimed to investigate the value of…
View article: Dynamics of Donor-Derived Cell-Free DNA at the Early Phase After Pediatric Kidney Transplantation: A Prospective Cohort Study
Dynamics of Donor-Derived Cell-Free DNA at the Early Phase After Pediatric Kidney Transplantation: A Prospective Cohort Study Open
Background: Donor-derived cell-free DNA (ddcfDNA) has been suggested as an indicator of allograft injury in adult and pediatric kidney transplantation (KTx). However, the dynamics of ddcfDNA in pediatric KTx have not been investigated. In …
View article: Additional file 1 of MicroRNA profile of circulating CD4+ T cells in aged patients with atherosclerosis obliterans
Additional file 1 of MicroRNA profile of circulating CD4+ T cells in aged patients with atherosclerosis obliterans Open
Additional file 1. The supplementary figures and tables.
View article: Engineered Small Extracellular Vesicles as a FGL1/PD‐L1 Dual‐Targeting Delivery System for Alleviating Immune Rejection (Adv. Sci. 3/2022)
Engineered Small Extracellular Vesicles as a FGL1/PD‐L1 Dual‐Targeting Delivery System for Alleviating Immune Rejection (Adv. Sci. 3/2022) Open
Small Extracellular Vesicles The simultaneous high expression of LAG‐3 and PD‐1 on T cells in cardiac transplantation mouse models and clinical renal transplantation patients provides the possibility to establish immune tolerance by giving…
View article: Additional file 2 of MicroRNA profile of circulating CD4+ T cells in aged patients with atherosclerosis obliterans
Additional file 2 of MicroRNA profile of circulating CD4+ T cells in aged patients with atherosclerosis obliterans Open
Additional file 2. Raw data sheets of miRNA screening and pathway analysis.
View article: Engineered Small Extracellular Vesicles as a FGL1/PD‐L1 Dual‐Targeting Delivery System for Alleviating Immune Rejection
Engineered Small Extracellular Vesicles as a FGL1/PD‐L1 Dual‐Targeting Delivery System for Alleviating Immune Rejection Open
There is an urgent need for developing new immunosuppressive agents due to the toxicity of long‐term use of broad immunosuppressive agents after organ transplantation. Comprehensive sample analysis revealed dysregulation of FGL1/LAG‐3 and …
View article: An accessible insight into genetic findings for transplantation recipients with suspected genetic kidney disease
An accessible insight into genetic findings for transplantation recipients with suspected genetic kidney disease Open
Determining the etiology of end-stage renal disease (ESRD) constitutes a great challenge in the context of renal transplantation. Evidence is lacking on the genetic findings for adult renal transplant recipients through exome sequencing (E…