Longxin Deng
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View article: End-to-end deep learning model for the diagnosis and segmentation of primary retroperitoneal neoplasm: a multicenter cohort study
End-to-end deep learning model for the diagnosis and segmentation of primary retroperitoneal neoplasm: a multicenter cohort study Open
This study was supported by the National Natural Science Foundation of China (82272905 and 82473385).
View article: Artificial intelligence in prostate cancer
Artificial intelligence in prostate cancer Open
Prostate cancer (PCa) ranks as the second most prevalent malignancy among men worldwide. Early diagnosis, personalized treatment, and prognosis prediction of PCa play a crucial role in improving patients’ survival rates. The advancement of…
View article: Function and mechanism of lactylation in health and diseases: a comprehensive review
Function and mechanism of lactylation in health and diseases: a comprehensive review Open
Lactylation, the post-translational modification of proteins by lactate, has emerged as a novel and dynamic regulatory mechanism in cellular metabolism and signaling. The lactylation proteome represents a frontier in the study of cellular …
View article: Multimodal deep learning model for predicting homologous recombination deficiency in prostate cancer: an international multi-cohort study
Multimodal deep learning model for predicting homologous recombination deficiency in prostate cancer: an international multi-cohort study Open
Accurate prediction of homologous recombination deficiency (HRD) status is crucial for effective management of prostate cancer (PCa). However, genetic testing is expensive and inaccessible. We propose a multimodal deep learning approach th…
View article: Arsenic exposure provoked prostatic PANoptosis by inducing mitochondrial dysfunction in mice and WPMY-1 cells
Arsenic exposure provoked prostatic PANoptosis by inducing mitochondrial dysfunction in mice and WPMY-1 cells Open
Inorganic arsenic, a widespread environmental toxicant, significantly contributes to prostate injury. However, the exact cellular mechanisms remain unclear. This study explored the involvement of pyroptosis, apoptosis, and necroptosis (PAN…
View article: Harnessing artificial intelligence for prostate cancer management
Harnessing artificial intelligence for prostate cancer management Open
View article: Integrating single-cell and bulk sequencing data to identify glycosylation-based genes in non-alcoholic fatty liver disease-associated hepatocellular carcinoma
Integrating single-cell and bulk sequencing data to identify glycosylation-based genes in non-alcoholic fatty liver disease-associated hepatocellular carcinoma Open
Background The incidence of non-alcoholic fatty liver disease (NAFLD) associated hepatocellular carcinoma (HCC) has been increasing. However, the role of glycosylation, an important modification that alters cellular differentiation and imm…
View article: Artificial intelligence-aided detection for prostate cancer with multimodal routine health check-up data: an Asian multi-center study
Artificial intelligence-aided detection for prostate cancer with multimodal routine health check-up data: an Asian multi-center study Open
Background: The early detection of high-grade prostate cancer (HGPCa) is of great importance. However, the current detection strategies result in a high rate of negative biopsies and high medical costs. In this study, the authors aimed to …
View article: Artificial Intelligence-Aided Detection for Prostate Cancer with Multi-Modal Routine Health Check-Up Data: An Asian Multi-Center Study
Artificial Intelligence-Aided Detection for Prostate Cancer with Multi-Modal Routine Health Check-Up Data: An Asian Multi-Center Study Open
View article: Multi-Modal Deep Learning Model for Predicting Homologous Recombination Deficiency in Prostate Cancer: An International Multi-Cohort Study
Multi-Modal Deep Learning Model for Predicting Homologous Recombination Deficiency in Prostate Cancer: An International Multi-Cohort Study Open