Lorène Gonnin
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View article: Structural and functional study of the respiratory syncytial virus nucleocapsid
Structural and functional study of the respiratory syncytial virus nucleocapsid Open
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and pneumonia in young children. It is also responsible for severe respiratory infections in elderly or immunocompromised people. There is no vaccine or specific treat…
View article: Structural landscape of the Respiratory Syncytial Virus nucleocapsids
Structural landscape of the Respiratory Syncytial Virus nucleocapsids Open
Human Respiratory Syncytial Virus (RSV) is a prevalent cause of severe respiratory infections in children and the elderly. The viral genome, enwrapped by the nucleoprotein N into a helical nucleocapsid (NC), is a template for the viral RNA…
View article: Interactions between the Nucleoprotein and the Phosphoprotein of Pneumoviruses: Structural Insight for Rational Design of Antivirals
Interactions between the Nucleoprotein and the Phosphoprotein of Pneumoviruses: Structural Insight for Rational Design of Antivirals Open
Pneumoviruses include pathogenic human and animal viruses, the most known and studied being the human respiratory syncytial virus (hRSV) and the metapneumovirus (hMPV), which are the major cause of severe acute respiratory tract illness in…
View article: Depletion of TAX1BP1 Amplifies Innate Immune Responses during Respiratory Syncytial Virus Infection
Depletion of TAX1BP1 Amplifies Innate Immune Responses during Respiratory Syncytial Virus Infection Open
Respiratory syncytial virus (RSV), which is the leading cause of lower respiratory tract illness in infants, remains a medical problem in the absence of a vaccine or efficient treatment. This virus is also recognized as a main pathogen in …
View article: Depletion of TAX1BP1 amplifies innate immune responses during respiratory syncytial virus infection
Depletion of TAX1BP1 amplifies innate immune responses during respiratory syncytial virus infection Open
Respiratory syncytial virus (RSV) is the main cause of acute respiratory infections in young children, and also has a major impact in the elderly and immunocompromised people. In the absence of vaccine or efficient treatment, a better unde…