Lori A. Bateman
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View article: Classifying COVID-19 hospitalizations in epidemiology cohort studies: The C4R study
Classifying COVID-19 hospitalizations in epidemiology cohort studies: The C4R study Open
Rationale Robust COVID-19 outcomes classification is important for ongoing epidemiology research on acute and post-acute COVID-19 conditions. Protocolized medical record review is an established method to validate endpoints for clinical tr…
View article: Classifying COVID-19 hospitalizations in epidemiology cohort studies: The C4R study
Classifying COVID-19 hospitalizations in epidemiology cohort studies: The C4R study Open
RATIONALE: Robust COVID-19 outcomes classification is important for ongoing epidemiology research on acute and post-acute COVID-19 conditions. Protocolized medical record review is an established method to validate endpoints for clinical t…
View article: Vessel and Airway Characteristics in One-Year Computed Tomography–defined Rapid Emphysema Progression: SPIROMICS
Vessel and Airway Characteristics in One-Year Computed Tomography–defined Rapid Emphysema Progression: SPIROMICS Open
Rationale: Rates of emphysema progression vary in chronic obstructive pulmonary disease (COPD), and the relationships with vascular and airway pathophysiology remain unclear. Objectives: We sought to determine if indices of p…
View article: Design of the SPIROMICS Study of Early COPD Progression: SOURCE Study
Design of the SPIROMICS Study of Early COPD Progression: SOURCE Study Open
SOURCE should provide novel insights into the natural history of lung disease in younger individuals with a smoking history, and its biological basis.
View article: Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease
Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease Open
"Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease." American Journal of Respiratory and Critical Care Medicine, 208(6), pp. 657–665
View article: P392: Genomic medicine and primary care: The Alabama Genomic Health Initiative*
P392: Genomic medicine and primary care: The Alabama Genomic Health Initiative* Open
View article: Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD
Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD Open
View article: Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study
Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study Open
Rationale: Chronic obstructive pulmonary disease (COPD) is defined by fixed spirometric ratio, FEV1/FVC < 0.70 after inhaled bronchodilators. However, the implications of variable obstruction (VO), in which the prebroncho…
View article: Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease
Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease Open
Rationale: Chronic obstructive pulmonary disease (COPD) is variable in its development. Lung microbiota and metabolites collectively may impact COPD pathophysiology, but relationships to clinical outcomes in milder disease are uncle…
View article: Amount and intensity effects of exercise training alone versus a combined diet and exercise lifestyle intervention on health-related quality of life in the STRRIDE-PD randomized trial
Amount and intensity effects of exercise training alone versus a combined diet and exercise lifestyle intervention on health-related quality of life in the STRRIDE-PD randomized trial Open
Introduction To determine the relative contributions of various amounts and intensities of exercise alone to a combined lifestyle intervention on health-related quality of life (HrQoL) measures. Research design and methods Participants (n=…
View article: Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort
Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort Open
The %predFEF25-75% provides additional information about disease manifestation beyond FEV1. These associations may reflect loss of elastic recoil and air trapping from emphysema and intrinsic small airways disease. Th…
View article: Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in COPD
Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in COPD Open
View article: Comparative Impact of Depressive Symptoms and FEV<sub>1</sub>% on Chronic Obstructive Pulmonary Disease
Comparative Impact of Depressive Symptoms and FEV<sub>1</sub>% on Chronic Obstructive Pulmonary Disease Open
Rationale: Individuals with chronic obstructive pulmonary disease (COPD) have a high prevalence of depression, which is associated with increased COPD hospitalizations and readmissions. Objectives: Examine the impact of depre…
View article: Aerobic Versus Resistance Training Effects on Ventricular-Arterial Coupling and Vascular Function in the STRRIDE-AT/RT Trial
Aerobic Versus Resistance Training Effects on Ventricular-Arterial Coupling and Vascular Function in the STRRIDE-AT/RT Trial Open
Background: The goal was studying the differential effects of aerobic training (AT) vs. resistance training (RT) on cardiac and peripheral arterial capacity on cardiopulmonary (CP) and peripheral vascular (PV) function in sedentary and obe…
View article: Aerobic, Resistance, and Combination Training on Health-Related Quality of Life: The STRRIDE-AT/RT Randomized Trial
Aerobic, Resistance, and Combination Training on Health-Related Quality of Life: The STRRIDE-AT/RT Randomized Trial Open
Purpose: The main purpose of this study was to determine the differential effects of aerobic training (AT), resistance training (RT), and a combination of aerobic and resistance training (AT/RT) on changes in self-rated HrQoL measures, inc…
View article: Insights from Mid-Expiratory Flow Rate (FEF<sub>25-75%</sub>) in Ever-Smokers with Preserved Lung Function in the Subpopulations and Intermediate Markers in COPD Study (SPIROMICS) Cohort
Insights from Mid-Expiratory Flow Rate (FEF<sub>25-75%</sub>) in Ever-Smokers with Preserved Lung Function in the Subpopulations and Intermediate Markers in COPD Study (SPIROMICS) Cohort Open
View article: Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD
Associations Among 25-Hydroxyvitamin D Levels, Lung Function, and Exacerbation Outcomes in COPD Open
View article: The Effects of Rare <i>SERPINA1</i> Variants on Lung Function and Emphysema in SPIROMICS
The Effects of Rare <i>SERPINA1</i> Variants on Lung Function and Emphysema in SPIROMICS Open
Rationale: The role of PI (protease inhibitor) type Z heterozygotes and additional rare variant genotypes in the gene encoding alpha-1 antitrypsin, SERPINA1 (serpin peptidase inhibitor, clade A, member 1), in determining chro…
View article: Development of a Workplace Intervention for Child Care Staff: Caring and Reaching for Health’s (CARE) Healthy Lifestyles Intervention
Development of a Workplace Intervention for Child Care Staff: Caring and Reaching for Health’s (CARE) Healthy Lifestyles Intervention Open
Child care staff are among the lowest wage workers, a group at increased risk for a wide array of chronic diseases. To date, the health of child care staff has been largely ignored, and there have been very few interventions designed for c…
View article: Workplace health and safety intervention for child care staff: Rationale, design, and baseline results from the CARE cluster randomized control trial
Workplace health and safety intervention for child care staff: Rationale, design, and baseline results from the CARE cluster randomized control trial Open
Baseline data demonstrate several serious health risks, confirming the importance of workplace interventions in child care.
View article: The Health and Working Conditions of Women Employed in Child Care
The Health and Working Conditions of Women Employed in Child Care Open
Over one million women are employed in child care and are among the lowest wage workers in the US. The health and working conditions of 674 child care workers (118 administrators and 556 staff) from 74 centers is described using baseline d…
View article: Does a lack of physical activity explain the rheumatoid arthritis lipid profile?
Does a lack of physical activity explain the rheumatoid arthritis lipid profile? Open
View article: Association of the Composite Inflammatory Biomarker GlycA, with Exercise‐Induced Changes in Body Habitus in Men and Women with Prediabetes
Association of the Composite Inflammatory Biomarker GlycA, with Exercise‐Induced Changes in Body Habitus in Men and Women with Prediabetes Open
GlycA is a new composite measure of systemic inflammation and a predictor of many inflammatory diseases. GlycA is the nuclear magnetic resonance spectroscopy‐derived signal arising from glucosamine residues on acute‐phase proteins. This st…
View article: The Health and Working Conditions of Women Employed in Child Care
The Health and Working Conditions of Women Employed in Child Care Open
Over one million women are employed in child care and are among the lowest wage workers in the US. The health and working conditions of 674 child care workers (118 administrators and 556 staff) from 74 centers is described using baseline d…
View article: Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individuals: a randomised controlled trial
Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individuals: a randomised controlled trial Open
View article: A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls
A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls Open
GlycA provides an integrated measure of inflammation with contributions from traditional inflammatory markers and cardio-metabolic sources, dominated by inflammatory markers in persons with RA and cardio-metabolic factors in those without.
View article: Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individuals: a randomised controlled trial
Effects of exercise training alone vs a combined exercise and nutritional lifestyle intervention on glucose homeostasis in prediabetic individuals: a randomised controlled trial Open
Although the Diabetes Prevention Program (DPP) established lifestyle changes (diet, exercise and weight loss) as the ‘gold standard’ preventive therapy for diabetes, the relative contribution of exercise alone to the overall utility of the…
View article: The effects of aerobic, resistance, and combination training on insulin sensitivity and secretion in overweight adults from STRRIDE AT/RT: a randomized trial
The effects of aerobic, resistance, and combination training on insulin sensitivity and secretion in overweight adults from STRRIDE AT/RT: a randomized trial Open
Most health organizations recommend a combination of aerobic training (AT) and resistance training (RT), yet few studies have compared their acute (within 24 h of the last exercise bout) and sustained (after 14 days of no exercise training…