Louis Paradis
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View article: Dupilumab in Eosinophilic Gastrointestinal Disorders With Extraesophageal Involvement: A Pediatric Case Series and Systematic Review
Dupilumab in Eosinophilic Gastrointestinal Disorders With Extraesophageal Involvement: A Pediatric Case Series and Systematic Review Open
Dupilumab has proven effective in the treatment of eosinophilic esophagitis (EoE) in randomized controlled trials. Its efficacy in other, less common and generally more severe eosinophilic gastrointestinal disorders (EGIDs) is scientifical…
View article: HLH-like Hypersensitivity Reaction Secondary to Prolonged Piperacillin/Tazobactam: A Case Series
HLH-like Hypersensitivity Reaction Secondary to Prolonged Piperacillin/Tazobactam: A Case Series Open
Background Prolonged (>10 days) use of intravenous (IV) piperacillin/tazobactam has been associated with a risk of developing hemophagocytic lymphohistiocytosis (HLH) syndrome. However, clinical and biological descriptions of this rare …
View article: Use of a 24-Hour Hotline vs Voicemail for Off-Hour Support During Oral Immunotherapy for Food Allergy
Use of a 24-Hour Hotline vs Voicemail for Off-Hour Support During Oral Immunotherapy for Food Allergy Open
View article: Predictors of support line utilization by patients undergoing oral immunotherapy
Predictors of support line utilization by patients undergoing oral immunotherapy Open
View article: Effect‐modifying impact of age on sex‐based differences during oral immunotherapy
Effect‐modifying impact of age on sex‐based differences during oral immunotherapy Open
International audience
View article: Abatacept to induce remission of peanut allergy during oral immunotherapy (ATARI): protocol for a phase 2a randomized controlled trial
Abatacept to induce remission of peanut allergy during oral immunotherapy (ATARI): protocol for a phase 2a randomized controlled trial Open
Context While oral immunotherapy (OIT) has been shown to promote the remission of mild peanut allergy in young children, there is still an unmet need for a disease-modifying intervention for older patients and those with severe diseases. I…
View article: Delayed‐type hypersensitivity gastrointestinal symptoms induced by food oral immunotherapy and efficiently treated by dupilumab: A case report
Delayed‐type hypersensitivity gastrointestinal symptoms induced by food oral immunotherapy and efficiently treated by dupilumab: A case report Open
International audience
View article: Efficacy of high-dose inhaled salbutamol for the treatment of gastro-intestinal anaphylaxis.
Efficacy of high-dose inhaled salbutamol for the treatment of gastro-intestinal anaphylaxis. Open
Background: Abdominal pain is a frequent symptom of IgE-mediated food allergy with limited therapeutic options. Visceral smooth muscle cell relaxation can be induced by activation of the beta-adrenergic receptors. Objective: To evaluate th…
View article: Supplementary Material for: Specific IgE to Total IgE Ratio Does Not Improve Peanut Diagnostic Accuracy in Adults
Supplementary Material for: Specific IgE to Total IgE Ratio Does Not Improve Peanut Diagnostic Accuracy in Adults Open
Background: Peanut specific IgE (sIgE) can lead to false-positive results. Objective: We aimed to assess whether peanut sIgE to total IgE (tIgE) ratio improves accuracy in predicting clinical reactivity to peanu…
View article: Sensitivity and specificity of double-blinded penicillin skin testing in relation to oral provocation with amoxicillin in children
Sensitivity and specificity of double-blinded penicillin skin testing in relation to oral provocation with amoxicillin in children Open
View article: Anaphylaxis to clindamycin following cutaneous exposure
Anaphylaxis to clindamycin following cutaneous exposure Open
View article: Correction to: Protocol for a double-blind, randomized controlled trial on the dose-related efficacy of omalizumab in multi-food oral immunotherapy
Correction to: Protocol for a double-blind, randomized controlled trial on the dose-related efficacy of omalizumab in multi-food oral immunotherapy Open
View article: Protocol for a double-blind, randomized controlled trial on the dose-related efficacy of omalizumab in multi-food oral immunotherapy
Protocol for a double-blind, randomized controlled trial on the dose-related efficacy of omalizumab in multi-food oral immunotherapy Open
Background Previous proof-of-concept studies have shown that a short course of omalizumab can safely accelerate the oral immunotherapy schedule for multiple allergens simultaneously. Considering the high cost of medication, the dose-relate…
View article: Skin Test Boosting Effect In Amoxicillin Allergic Children
Skin Test Boosting Effect In Amoxicillin Allergic Children Open
View article: Total IgE influences the cutoff values of specific IgE with 95% PPV
Total IgE influences the cutoff values of specific IgE with 95% PPV Open
View article: Sensitivity and Specificity of Penicillin Skin Testing for IgE-Mediated Allergy to Amoxicillin: A Double-Blinded Prospective Diagnostic Accuracy Study with Systematic Review and Meta-Analysis
Sensitivity and Specificity of Penicillin Skin Testing for IgE-Mediated Allergy to Amoxicillin: A Double-Blinded Prospective Diagnostic Accuracy Study with Systematic Review and Meta-Analysis Open
View article: Introduction of peanuts in younger siblings of children with peanut allergy: A follow-up
Introduction of peanuts in younger siblings of children with peanut allergy: A follow-up Open
View article: Determining optimal prioritization system for food oral immunotherapy in a tertiary care setting
Determining optimal prioritization system for food oral immunotherapy in a tertiary care setting Open
View article: Age Does Not Affect The Safety of Progressive Food Introduction in Food Allergic Children with High Reaction Thresholds
Age Does Not Affect The Safety of Progressive Food Introduction in Food Allergic Children with High Reaction Thresholds Open
View article: Update on oral immunotherapy for egg allergy
Update on oral immunotherapy for egg allergy Open
Oral immunotherapy (OIT) is an emerging treatment of IgE-mediated egg allergy. In the past decade, a multitude of studies have assessed the potential for egg OIT to induce clinical desensitization. The following review will evaluate the ef…
View article: Canadian Society of Allergy and Clinical Immunology annual scientific meeting 2016
Canadian Society of Allergy and Clinical Immunology annual scientific meeting 2016 Open
View article: Amoxicillin Reuse after a Five-Day Challenge for the Evaluation of Delayed-Type Penicillin Allergy in Children
Amoxicillin Reuse after a Five-Day Challenge for the Evaluation of Delayed-Type Penicillin Allergy in Children Open
View article: Comparison of ImmunoCAP and Immulite serum specific IgE assays for the assessment of egg allergy
Comparison of ImmunoCAP and Immulite serum specific IgE assays for the assessment of egg allergy Open
Egg specific IgE levels are frequently used in combination with skin-prick tests to guide clinical decisions and to monitor egg allergy evolution in children. We compared both Immulite and ImmunoCAP egg specific IgE assays in egg allergic …
View article: Powder milk: a user-friendly and safe product for heated-milk food challenge?
Powder milk: a user-friendly and safe product for heated-milk food challenge? Open
Challenge with instant skim milk powder could be a safe, convenient and easily standardizable alternative to home baked food for heated milk challenge. Further controlled studies are needed before this can be implemented to practice.
View article: Comparison of Unicap and Immulite Serum Specific IgE Assays for the Assessment of Egg Allergies
Comparison of Unicap and Immulite Serum Specific IgE Assays for the Assessment of Egg Allergies Open