Explanipedia

The Prognostic Value of the Hedgehog Signaling Pathway in Ovarian Cancer Open

Noor Salman, Lars Hanker, Balázs Győrffy, Áron Bartha, Louisa Proppe , et al. · 2025

The hedgehog pathway is a major regulator of cell growth and differentiation during embryogenesis and early development. The literature suggests that variations in this pathway’s genes play a role in tumor progression and response to thera…

Prognostic and clinical heterogeneity of PD1 and PD-L1- immunohistochemical scores in endometrial cancers Open

Louisa Proppe, Tobias Jagomast, S Beume, Frank Köster, Karen Bräutigam , et al. · 2025

Prognostic and Clinical Heterogeneity of PD1 and PD-L1- Immunohistochemical Scores in Endometrial Cancers Open

Louisa Proppe, Tobias Jagomast, Sophie Beume, Frank Köster, Karen Bräutigam , et al. · 2024

Introduction: PD1/PD-L1 inhibition (ICi) has recently become a new standard of care for patients with advanced MMR-deficient (MMRd) endometrial cancers. Nevertheless, response to immunotherapy is more complex than the presence of a single …

Overexpression of the orphan nuclear receptor NR2F6 is associated with improved survival across molecular subgroups in endometrial cancer patients Open

Louisa Proppe, Tobias Jagomast, S Beume, Luise Klapper, Georgios Gitas , et al. · 2023

EP147/#165 Overexpression of the orphan nuclear receptor NR2F6 is associated with an improved survival in endometrial cancer patients Open

Louisa Proppe, Tobias Jagomast, Julika Ribbat‐Idel, Sophie Beume, Georgios Gitas , et al. · 2022

Objectives NR2F6 (nuclear receptor subfamily 2 group F member 6, also called Ear-2) is known to be an orphan nuclear receptor being an intracellular immune checkpoint in effector T cells. It might play an essential role for tumor developme…

Surgical treatment of endometrioid endometrial carcinoma - laparotomy versus laparoscopy Open

Sascha Baum, İbrahim Alkatout, Louisa Proppe, Christos P. Kotanidis, Achim Rody , et al. · 2022

The oncological outcome of laparoscopy was similar to that of laparotomy in the treatment of patients with endometrial cancer. However, surgical outcomes and morbidity rates were significantly better in patients treated by laparoscopy. Cli…

2022-RA-1344-ESGO Endometrial cancer patients with an overexpression of the orphan nuclear receptor NR2F6 show an improved survival Open

Louisa Proppe, Tobias Jagomast, Julika Ribbat‐Idel, Sophie Beume, Georgios Gitas , et al. · 2022

Risk factor analysis in women who underwent trial of labor after cesarean section: a multicenter study in Germany Open

George Gitas, İbrahim Alkatout, Kubilay Ertan, Achim Rody, Louisa Proppe , et al. · 2022

Nearly two thirds of women with a history of CD achieve VBAC in Germany. Previous vaginal birth and the augmentation of labor with oxytocin are positively associated with the achievement of VBAC and no major perinatal complications. The de…

Distribution of HPV Subtypes in Diverse Anogenital and Oral Samples from Women and Correlation of Infections with Neoplasia of the Cervix Open

Karen Bräutigam, Stefanie Meier, Sabina Meneder, Louisa Proppe, Katharina Stroschein , et al. · 2022

Background: Cancers and intraepithelial lesions of different anogenital areas as well as oral cancer are associated with human papilloma virus (HPV) infections. Methods: In this study cervical, vaginal, vulvar, anal, and oral samples were …

Impact of lymphadenectomy on short- and long-term complications in patients with endometrial cancer Open

Louisa Proppe, İbrahim Alkatout, Ricarda Koch, Sascha Baum, Christos P. Kotanidis , et al. · 2022

Long-term satisfaction of patients after laparoscopic and robotic-assisted hysterectomy Open

Georgios Gitas, İbrahim Alkatout, Louisa Proppe, Lars Hanker, Leila Allahqoli , et al. · 2021

Introduction Da-Vinci-Xi is the most recent device used in gynecologic robotic surgery. The aim of the present study was to compare the long-term satisfaction of patients who had undergone conventional laparoscopic hysterectomy or robotic …

Impact of Lymphadenectomy on Short- and Long-term Complications in Patients With Endometrial Cancer Open

Louisa Proppe, İbrahim Alkatout, Ricarda Koch, Sascha Baum, Christos P. Kotanidis , et al. · 2021

IntroductionEarly endometrial cancer is primarily treated surgically via hysterectomy, adenectomy and, depending on tumor stage and subtype, lymphadenectomy. Systematic lymph node dissection is known to cause surgical complications. The ai…

Influence of the second stage of labor on maternal and neonatal outcomes in vaginal births after caesarean section: a multicenter study in Germany Open

Georgios Gitas, Louisa Proppe, A. Kubilay Ertan, Sascha Baum, Achim Rody , et al. · 2021

Background The American College of Obstetricians and Gynecologists (ACOG) introduced a new standard of care in 2014, extending the duration of the second stage of labor in order to reduce caesarean delivery (CD) rates and its severe compli…

Surgical outcomes of conventional laparoscopic and robotic‐assisted hysterectomy Open

Georgios Gitas, İbrahim Alkatout, Louisa Proppe, Nele Werner, Achim Rody , et al. · 2021

Introduction The aim of the present study was to compare surgical outcomes of total laparoscopic hysterectomy with those of the robotic approach using the da Vinci Xi system. Methods Patients who underwent hysterectomy with da Vinci Xi for…

A risk factor analysis of complications after surgery for vulvar cancer Open

Georgios Gitas, Louisa Proppe, Sascha Baum, M. Kruggel, Achim Rody , et al. · 2021

Is ABO blood group a risk or prognostic factor for patients with endometrioid endometrial cancer? A retrospective analysis in Germany. Open

Georgios Gitas, Louisa Proppe, İbrahim Alkatout, Dimitrios Tsolakidis, Achim Rody , et al. · 2020

Blood group screening would probably not be helpful in the diagnosis of endometrioid endometrial carcinomas in early stages compared to the current gold standard. Furthermore, a specific blood group does not increase either the risk of rec…

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